Vonefi 20 mg Tablet (10 Tab)

Vonefi 20 Tablet Overview:

Vonefi 20 Tablet is a medicine, used to reduce the stomach acid production and effectively treats conditions like stomach ulcers, pain from acid reflux, and other conditions caused by high acidity. Vonefi 20 Tablet helps to relief heartburn associated with erosive esophagitis (inflammation in your esophagus) in adults. Additionally, Vonefi 20 Tablet prevents the recurrence of stomach and duodenal ulcers when taking aspirin or other anti-inflammatory drugs (NSAIDs). Vonefi 20 Tablet may also be prescribed alongside other medications to treat Helicobacter pylori bacterial infection.

Composition of Vonefi 20 Tablet:

Each film coated tablet contains: Vonoprazan Fumarate equivalent to Vonoprazan: 20 mg and Excipients q.s.

Colours: Ferric Oxide USP NF(Red) and Titanium Dioxide IP

Uses and Benefits of Vonefi 20 Tablet:

· Vonefi 20 Tablet used for the treatment of gastroesophageal reflux disease (GERD) and its associated conditions like heartburn, acidity or indigestion.

· Vonefi 20 Tablet used to treat Helicobacter pylori bacterial infection in combination with aspirin or other anti-inflammatory drugs (NSAIDs).

How Vonefi 20 Tablet Works:

Vonefi 20 Tablet contains vonoprazan, a potassium-competitive acid blocker, which is a type of proton pump inhibitor (PPI). By blocking the final step of acid production in the stomach, vonoprazan reduces the amount of acid made in the stomach and relieves acid-related disorders.

Dosage of Vonefi 20 Tablet:

• Usage Direction

Vonefi 20 Tablet exactly as prescribed by your doctor, and follow the recommended dosage and schedule. Vonefi 20 should be swallowed as whole without crushing, chewing, or breaking it, and ideally at the same time each day. Do not stop or alter the dose of Vonefi 20 Tablet without consulting your doctor, as this may prevent you from achieving the desired outcome. Ask your doctor or pharmacist to explain any administration procedures you do not understand.

• Missed Dose

If you miss a dose of Vonefi 20 Tablet, take it as soon as it is remembered. If it is time for your next dose of Vonefi 20, skip the missed dose and resume your regular schedule. Avoid taking two doses to compensate for a missed one.

• Over Dose

If you accidentally take Vonefi 20 Tablet more than your prescribed dose, seek immediate medical advice, as this may lead to serious side effects.

Contraindications of Vonefi 20 Tablet:

Do not take Vonefi 20 Tablet if you are hypersensitive or allergic to Vonoprazan or any of the ingredients of this medicine or if you have ever experienced an allergic reaction including anaphylactic shock.

Precautions & Warnings of Vonefi 20 Tablet:

Before starting Vonefi 20 Tablet, tell your doctor if you have any of these: gastric malignancy, diarrhea and inflammation of the colon (clostridium dicile), serious colitis including pseudomembranous colitis, Acute Tubulointerstitial Nephritis (TIN), bone fracture, severe cutaneous adverse reactions, Vitamin B12 Deficiency, hypomagnesemia and Mineral Metabolism, interactions with diagnostic investigations for neuroendocrine tumors or fundic gland polyps.

Side Effects of Vonefi 20 Tablet:

Vonefi 20 Tablet may also cause some side effects, most of which do not require medical attention and typically go away as your body adapts to the medication. However, if these effects persist, consult your doctor. These may include diarrhoea, nausea and vomiting, constipation, abdominal pain, skin rash.

Safety Related Concerns of Vonefi 20 Tablet:

• Pregnancy

If you are pregnant or planning to become pregnant, consult your doctor to determine if Vonefi 20 Tablet is safe for you to take.

• Breastfeeding

Breastfeeding mothers are advised to avoid Vonefi 20 Tablet as it may pass through breast milk and can cause side effects in breastfed babies. Therefore, it is important to consult your doctor before taking Vonefi 20 while breastfeeding.

• Alcohol

Although no direct interaction between Vonefi 20 Tablet and alcohol has been found, but alcohol can increase stomach acid, worsen acid reflux, and increase the risk of side effects such as dizziness and irregular heartbeat. Therefore, it's advisable to avoid alcohol while undergoing treatment.

• Food or Interactions with Other Medicines

Avoid spicy or junk foods, citrus foods (Like oranges, lemons, grapefruits, acidic foods (tomatoes), high-fat foods, carbonated drinks (soda) while taking Vonefi 20 Tablet.

Consult your doctor if you are taking any herbal products or supplements while taking Vonefi 20 Tablet. As always, it is a good idea to consult your doctor or healthcare provider about your specific dietary needs while on Vonefi 20 Tablet.

• Driving

If you experience side effects such as dizziness or blurred vision, you should avoid driving or operating machinery while taking Vonefi 20 Tablet.

Storage of Vonefi 20 Tablet:

Vonefi 20 Tablet should be stored below 30°C.

Keep Vonefi 20 Tablet out of reach of children.

Note: Eating smaller, more frequent meals and maintaining a healthy diet can help improve your condition.

Frequently Asked Questions (FAQs) about Vonefi 20 Tablet:

1. What is the use of Vonefi 20 Tablet?

Vonefi 20 Tablet used for the treatment of gastroesophageal reflux disease (GERD) and its associated conditions like heartburn, acidity or indigestion. It is also used to treat Helicobacter pylori bacterial infection in combination with aspirin or other anti-inflammatory drugs (NSAIDs).

2. Is vonoprazan safer than omeprazole?

Vonoprazan and Omeprazole are both generally well tolerated. However, vonoprazan is more powerful and has a longer duration of action compared to traditional PPIs like omeprazole. Your doctor will prescribe the most suitable medication based on your condition. Avoid self-medicating.

3. When is the best time to take Vonefi 20 Tablet?

Take Vonefi 20 Tablet orally, with or without food, as recommended by your doctor based on your condition. Swallow the tablet whole without cutting, chewing, or breaking it, or it may not provide desired results. Once your symptoms are under control, your doctor may decide to discontinue the medication.

4. Does Vonefi 20 Tablet affect the kidneys?

Vonefi 20 Tablet has been associated with acute kidney injury. The long term use of vonoprazan may lead to kidney damage by causing acute tubulointerstitial nephritis (TIN), a condition that involves swelling of the kidney tubules and may impact kidney function. It is essential to monitor kidney health while using this Vonefi 20 Tablet. If you notice symptoms such as changes in urine output, blood in the urine, or swelling in your body, contact your healthcare provider immediately.

5. Can I take vonoprazan and pantoprazole together?

Taking vonoprazan and pantoprazole together is generally not recommended unless your doctor advises it. Both are proton pump inhibitors (PPIs), and using them together could raise the risk of side effects without offering extra benefits. Your doctor will prescribe the best treatment for your condition, so it's important to follow their recommendations and avoid combining medications without their approval.

6. Which food should avoided while taking Vonefi 20 Tablet?

When taking Vonefi 20 Tablet, it's important to avoid foods that may irritate your stomach or increase acid production. These include oily and spicy foods, citrus fruits like oranges and lemons, tomato-based products, coffee, tea, cola, carbonated drinks, and chocolate. Additionally, try to avoid large meals right before bedtime, as they can aggravate acidity symptoms. Always follow your doctor's dietary advice for specific dietary recommendation.

References:

1. VONOGRESS Vonoprazan 10 mg and 20 mg Tablets. Accessed on 14.02.2025. Click Here

2. List of New Drugs approved in the year 2024 till date. Vonoprazan fumarate Bulk drug& Vonoprazan tablets 10mg/20 mg. Accessed on 14.02.2025. Click Here

3. HIGHLIGHTS OF PRESCRIBING INFORMATION. Accessed on 14.02.2025. Click Here

4. COMMENTARIES. Update on the Use of Vonoprazan: A Competitive Acid Blocker. Accessed on 14.02.2025. Click Here