Sacurise 100 mg Tablet (14 Tab)

Sacurise 100 mg Tablet Overview :

Sacurise 100 mg Tablet is a prescription medicine used to treat chronic heart failure with reduced ejection fraction (HFrEF). It contains a fixed-dose combination of Sacubitril (49 mg) and Valsartan (51 mg), belonging to the class of Angiotensin Receptor Neprilysin Inhibitors (ARNIs).
This medicine helps improve heart efficiency, reduce fluid overload, and lower the risk of cardiovascular death and hospitalization in patients with heart failure.

Composition of Sacurise 100 mg Tablet :

• Sacubitril – 49 mg
• Valsartan – 51 mg

Uses / Indications of Sacurise 100 mg Tablet :

• Chronic heart failure (HFrEF)
• Improves heart function and blood circulation
• Reduces hospitalization and mortality due to heart failure

How Sacurise 100 mg Tablet Works :

Sacubitril inhibits the enzyme neprilysin, which helps increase the levels of beneficial peptides that dilate blood vessels, reduce sodium retention, and ease the workload on the heart.
Valsartan blocks the angiotensin II receptor, preventing blood vessel constriction and lowering blood pressure.
Together, they help improve cardiac output and delay disease progression in heart failure patients.

Usage Direction of Sacurise 100 mg Tablet :

• As directed by your Doctor. Usually taken orally with or without food.
• Swallow whole with a glass of water. Do not crush or chew.
• Maintain the same time each day for consistent results.
• Do not skip or stop the medicine without your doctor’s advice.

Side Effects of Sacurise 100 mg Tablet :

Common side effects may include :

• Dizziness or light-headedness
• Low blood pressure (hypotension)
• Increased potassium levels (hyperkalaemia)
• Fatigue or weakness
• Kidney function changes
• Cough

Seek immediate medical attention if you experience facial swelling, difficulty breathing, chest pain, or fainting.

Precautions & Warnings for Sacurise 100 mg Tablet :

• Avoid during pregnancy or breastfeeding.
• Not recommended in severe kidney or liver disorders.
• Do not combine with ACE inhibitors or aliskiren. Maintain a 36-hour washout period if switching from an ACE inhibitor.
• Regularly monitor blood pressure, potassium, and kidney function.
• Inform your doctor about all ongoing medicines, especially diuretics, potassium supplements, or NSAIDs.

Storage instruction for Sacurise 100 mg Tablet :

• Store below 30°C in a cool, dry and hygienic place.
• Protect from moisture and direct sunlight.
• Keep out of reach of children.

Key Benefits of Sacurise 100 mg Tablet :

• Enhances heart pumping ability
• Reduces breathlessness and fatigue
• Lowers hospital admission rates in heart failure
• Improves survival and quality of life in heart failure patients

Frequently Asked Questions (FAQs) about Sacurise 100 mg Tablet :

1. What is Sacurise 100 mg Tablet used for?
It is used for treating chronic heart failure with reduced ejection fraction (HFrEF). It helps improve heart function and reduces the risk of hospitalization and death due to heart failure.

2. Can Sacurise 100 mg Tablet be used for high blood pressure?
Although it may lower blood pressure, it is not prescribed solely for hypertension. It is meant for patients with heart failure under medical supervision.

3. When should I take Sacurise 100 mg Tablet, morning or night?
You can take it at any fixed time of the day, preferably at the same time daily. Follow your doctor’s instructions.

4. Can I take Sacurise 100 mg Tablet along with other heart medicines?
Yes, but only under doctor’s advice. Your physician will adjust the doses to prevent interactions, especially with diuretics or ACE inhibitors.

5. What should I do if I miss a dose of Sacurise 100 mg Tablet?
Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip it — do not double the dose.

6. Does Sacurise 100 mg Tablet cause dizziness or low BP?
Yes, especially during the initial days of therapy. Stand up slowly from sitting or lying positions and avoid alcohol to minimize dizziness.

7. Can I stop taking Sacurise 100 mg Tablet if I feel better?
No. Stopping the medicine abruptly can worsen your heart condition. Continue as prescribed and consult your doctor before making any changes.

8. Is Sacurise 100 mg Tablet safe for elderly patients?
Yes, but older adults may be more sensitive to its effects. Monitoring of blood pressure, kidney function, and potassium is essential.

9. What foods should I avoid while taking Sacurise 100 mg Tablet?
Avoid potassium-rich foods (like bananas, oranges, or salt substitutes) unless advised by your doctor, as the medicine can increase potassium levels.

10. Can pregnant or breastfeeding women take Sacurise 100 mg Tablet?
No, it is unsafe during pregnancy and lactation. It may harm the unborn or nursing baby. Always consult a doctor before use.

References :

1. US FDA Label – Sacubitril/Valsartan (Entresto). Click Here

2. National Heart, Lung, and Blood Institute (NHLBI). Click Here

3. ScienceDirect – Angiotensin Receptor Neprilysin Inhibitors. Click Here

4. NCBI – Neprilysin Inhibition in Heart Failure. Click Here