Preva AS 150 mg Tablet (15 Tab)

Preva AS 150 Tablet Overview:

Preva AS 150 Tablet is a prescription medication that combines two active ingredients, clopidogrel and aspirin. It falls under the category of antiplatelet drugs, which are designed to help prevent the formation of harmful blood clots in the body. This tablet is commonly prescribed for individuals who have experienced heart-related issues, such as chest pain or a recent heart attack, or those at high risk of cardiovascular events like strokes. By thinning the blood and reducing clot risk, it supports better blood flow through narrowed vessels, but it should only be taken under a doctor's guidance due to potential risks like increased bleeding.

Composition:

Each film coated tablet contains- Clopidogrel Bisulphate equivalent to Clopidogrel 75 mg and Aspirin 150 mg

Colours: Ferric Oxide Red and Titanium Dioxide IP

Uses & Benefits of Preva AS 150 Tablet:

This tablet is primarily used to lower the chances of serious heart and blood vessel problems, including heart attacks, strokes, and death from clot-related issues. It is beneficial for people with acute coronary syndrome, which includes unstable chest pain or certain types of heart attacks, as well as those with peripheral artery disease where blood flow to the legs is poor. The combination of clopidogrel and aspirin provides dual protection by targeting different pathways in clot formation, making it more effective than a single agent in preventing clots after procedures like stent placement or in managing ongoing heart conditions. Additionally, it helps maintain overall cardiovascular health in high-risk patients by keeping blood vessels clearer.

Dosage of Preva AS 150 Tablet:

• Usage Direction

Preva AS 150 Tablet is typically taken once daily, preferably at the same time each day to maintain consistent levels in the body. It can be swallowed whole with a glass of water, and taking it with food is recommended to minimize any stomach discomfort from the aspirin component. Your doctor may start with a higher initial dose of clopidogrel if needed for faster action, but the standard maintenance is one tablet per day. Always follow the prescribed duration, which could be long-term, and do not stop without consulting your doctor, as abrupt discontinuation might increase clot risk.

• Missed Dose

If you forget to take your Preva AS 150 Tablet, take it as soon as you remember, unless it's nearly time for the next scheduled dose. In that case, skip the missed one and resume your regular routine without doubling up, as extra doses could heighten bleeding risks. Setting reminders or linking the dose to a daily habit, like mealtime, can help avoid misses. If you frequently forget, discuss with your doctor for tips or possible adjustments to your regimen.

• Overdose

An overdose of Preva AS 150 Tablet can lead to excessive bleeding, dizziness, nausea, ringing in the ears, or more severe symptoms like confusion or difficulty breathing. If you suspect an overdose, seek immediate medical attention by contacting emergency services, your doctor, or a poison control center. Do not attempt to manage it at home, and bring the medication packaging to help healthcare providers respond effectively.

How Preva AS 150 Tablet Works:

Preva AS 150 Tablet operates through its two components: clopidogrel inhibits a specific receptor on platelets to prevent them from activating and clumping together, while aspirin blocks the production of substances that promote platelet aggregation. Together, they make platelets less sticky, reducing the likelihood of clots forming in blood vessels, particularly in those hardened by plaque buildup. This action helps ensure smoother blood flow and lowers the risk of blockages that cause heart attacks or strokes, though the effectiveness can vary based on individual factors like genetics affecting how the body processes clopidogrel.

Contraindications of of Preva AS 150 Tablet:

This tablet should not be used if you have active bleeding conditions, such as stomach ulcers, brain hemorrhages, or bleeding disorders like hemophilia, as it can worsen bleeding. It's also contraindicated in cases of severe liver or kidney impairment, known allergies to clopidogrel, aspirin, or similar drugs, or if you have asthma triggered by aspirin-like medications. Avoid it during the third trimester of pregnancy or if breastfeeding, and check with your doctor if you have a history of nasal polyps or recent serious injuries.

Precautions & Warnings of Preva AS 150 Tablet:

Before starting Preva AS 150 Tablet, inform your doctor about any history of bleeding issues, liver or kidney problems, upcoming surgeries (including dental), or genetic factors that might affect drug processing. Monitor for signs of bleeding like unusual bruising, nosebleeds, or dark stools, and report them promptly. Elderly individuals may need closer monitoring due to higher sensitivity, and genetic testing might be recommended if the drug seems less effective. Use caution if you have gout or alcohol habits, as these can interact negatively, and always disclose all medications to avoid complications.

Side Effects of Preva AS 150 Tablet:

Common side effects include easy bruising, nosebleeds, stomach upset, diarrhea, or headaches, which often resolve as your body adjusts. More serious ones might involve severe bleeding, allergic reactions like rash or swelling, shortness of breath, or signs of liver issues such as yellowing skin. Aspirin in the mix can cause indigestion or heartburn, while clopidogrel might lead to fatigue or dizziness in some. If any effect persists or worsens, contact your doctor immediately to assess if adjustments are needed.

Pregnancy:

Preva AS 150 Tablet is generally not recommended during pregnancy, particularly in the first and second trimesters, as it may harm the developing baby by increasing bleeding risks or affecting fetal development. In the third trimester, it's strictly avoided due to potential complications like premature closure of a blood vessel in the fetus. If you're planning pregnancy or already pregnant, discuss alternatives with your doctor for safer options.

Important: Do not take this product during the last three months of pregnancy unless directed by a physician. Aspirin taken near the time of delivery may cause bleeding problem to both mother and child.

Breastfeeding:

This medication should be avoided while breastfeeding, as both clopidogrel and aspirin can pass into breast milk and potentially cause harm to the infant, such as increased bleeding or allergic reactions. If treatment is essential, your doctor might suggest stopping breastfeeding or switching to a different drug to ensure the baby's safety.

Food Interaction:

There are no major food restrictions with Preva AS 150 Tablet, but taking it with meals can help reduce stomach irritation from aspirin. Avoid excessive grapefruit or grapefruit juice, as it might interfere with how clopidogrel is processed in the body. Maintain a balanced diet, and consult your doctor if you have specific dietary concerns like high-fat meals that could affect absorption.

Alcohol:

Drinking alcohol while on Preva AS 150 Tablet can increase the risk of stomach bleeding or irritation due to aspirin's effects, and it may amplify dizziness or bleeding tendencies. It's best to limit or avoid alcohol altogether; if you consume it regularly, talk to your doctor about safe levels or alternatives to minimize risks.

Driving & Using Machinery:

This tablet might cause dizziness, headaches, or fatigue in some people, which could impair your ability to drive or operate machinery safely. If you experience these effects, avoid such activities until they subside. Your doctor can advise on whether it's safe based on your response to the medication.

Drug Interaction:

Preva AS 150 Tablet can interact with other medications, increasing bleeding risks when combined with NSAIDs like ibuprofen, blood thinners like warfarin, or antidepressants like SSRIs. It may also affect drugs processed by the liver, such as certain statins or antacids. Always inform your doctor about all prescriptions, over-the-counter drugs, or supplements to prevent harmful interactions and adjust doses if needed.

Storage Information:

Store below 25°C, in a dry place. Protect from light.

Keep all medicines out of reach of children.

Other Notes:

Regular blood tests may be required to monitor platelet function and ensure the drug is working effectively, especially if genetic factors are involved. Do not donate blood while taking this tablet or for at least a week after stopping, as it could affect recipients. If you're a smoker, quitting can enhance the benefits, and lifestyle changes like exercise and diet should complement the treatment.

Label Instruction: This product is not to be used in children below 12 years of age except under medical advice.

Frequently Asked Questions

1. What is Preva AS 150 Tablet used for?

It is used to prevent blood clots that can lead to heart attacks or strokes in people with heart conditions or poor blood circulation.

2. Can I take Preva AS 150 Tablet on an empty stomach?

It's better to take it with food to avoid stomach upset, but follow your doctor's advice.

3. What should I do if I experience bleeding while on this tablet?

Stop any activities that could cause injury and contact your doctor immediately if bleeding is unusual or doesn't stop.

4. Is Preva AS 150 Tablet safe for long-term use?

Yes, under medical supervision, but regular check-ups are needed to monitor for side effects like bleeding.

5. Can I drink coffee while taking this medication?

Moderate coffee is usually fine, but excessive caffeine might interact with aspirin; consult your doctor if concerned.

6. What if I'm allergic to aspirin?

Do not take this tablet; inform your doctor for alternative treatments.

7. Does Preva AS 150 Tablet affect blood pressure?

It doesn't directly lower blood pressure but helps with related heart issues; monitor with your doctor.

8. Can children take Preva AS 150 Tablet?

No, it's not studied or recommended for those under 18 years old.

9. What foods should I avoid?

Limit high-vitamin K foods if on other blood thinners, but no strict avoids unless advised.