Pentate Dsr Capsule (10 Cap)

• Pentate Dsr Capsule Overview:

Pentate Dsr Capsule is used for the treatment of GERD (gastroesophageal reflux disease), indigestion, and gastritis in which stomach acid flows back into the food pipe, leading to heartburn and possible esophageal injury. Pentate Dsr Capsule is composed of two main ingredients; Pantoprazole and Domperidone, is used in patients in which pantoprazole alone cannot control acid reflux. Pantoprazole reduces stomach acid production, while Domperidone helps improve stomach movement and prevents nausea. Together, they effectively manage acid reflux, heartburn, stomach pain, peptic ulcers, and other symptoms caused by hyper-acidity.

Composition of Pentate Dsr Capsule:

Each hard gelatin Pentate Dsr capsule contains: Pantoprazole Sodium equivalent to Pantoprazole 40 mg (as Gastro-resistant pellets), Domperidone 30 mg (as Prolonged-release pellets) and Excipients q.s.

Colours: Sunset Yellow FCF & Brilliant Blue FCF.

Colours used in empty hard gelatin capsule shells: Brilliant Blue FCF & Tartrazine.

• Uses and Benefits of Pentate Dsr Capsule:

Pentate Dsr Capsule is prescribed for the following conditions:

Manages Gastroesophageal Reflux Disease (GERD/Acid Reflux), where stomach acid backs up into the esophagus, leading to heartburn and irritation.

Relieves bloating, discomfort, and acid-related indigestion by reducing stomach acid production.

Reduces heartburn caused by acid reflux.

Eases gastritis caused by excess stomach acid or Helicobacter pylori bacterial infection.

Heals peptic ulcers by lowering stomach acid levels.

Provides relief from symptoms of acidity and hyperacidity, such as stomach pain, irritation, and discomfort.

• How Pentate Dsr Capsule Works:

Pentate Dsr Capsule contains two active ingredients, Pantoprazole and Domperidone, that work together to treat conditions caused by too much stomach acid and improve digestion.

Pantoprazole is a selective Proton Pump Inhibitor (PPI) that works by blocking the proton pump in the stomach lining, which is responsible for producing gastric acid. By inhibiting this enzyme, it effectively reduces stomach acid production, lowering acidity and helping to treat conditions like GERD, acid reflux, and peptic ulcers.

Domperidone, on the other hand, is a gastro-prokinetic and anti-nausea drug. It works by blocking dopamine receptors in the upper part of the digestive system, helping food move through the stomach and preventing nausea and vomiting.

• Dosage of Pentate Dsr Capsule:

Usage Direction

Take Pentate Dsr Capsule exactly as prescribed by your doctor, and follow the recommended dosage and schedule. Pentate Dsr Capsule should be swallowed as whole without crushing, chewing, or breaking it, and ideally at the same time each day. Do not stop or alter the dose of Pentate Dsr Capsule without consulting your doctor, as this may prevent you from achieving the desired outcome. Ask your doctor or pharmacist to explain any administration procedures you do not understand.

Missed Dose

If you miss a dose of Pentate Dsr Capsule, take it as soon as it is remembered. If it is time for your next dose of Pentate Dsr Capsule, skip the missed dose and resume your regular schedule. Avoid taking two doses to compensate for a missed one.

Over Dose

If you accidentally take Pentate Dsr Capsule more than your prescribed dose, seek immediate medical advice, as this may lead to serious side effects.

• Contraindications of Pentate Dsr Capsule:

Do not take Pentate Dsr Capsule if you are allergic to Pantoprazole, Domperidone, or any other ingredients of this medication, or if you have severe kidney disease.

Pentate Dsr should be avoided in patients with a prolactin-releasing pituitary tumor (prolactinoma), gastrointestinal problems, severe liver disease, stomach or intestinal bleeding, heart failure, or abnormal levels of potassium or magnesium in the blood.

• Precautions & Warnings of Pentate Dsr Capsule:

Before starting Pentate Dsr Capsule, inform your doctor if you have jaundice, severe liver or kidney problems, or if you are at risk of low vitamin B12 levels and are receiving long-term treatment with pantoprazole. Also, let your doctor know if you have a history of gastric ulcers or gastrointestinal surgery, or if you are taking HIV protease inhibitors like atazanavir. Additionally, notify your doctor if you have been on pantoprazole for more than 3 months or if you have experienced any skin reactions in the past.

• Side Effects of Pentate Dsr Capsule:

Pentate Dsr Capsule may cause some side effects, most of which do not require medical attention and typically go away as your body adjusts to the medication. However, if these effects persist, consult your doctor. These may include; headache, diarrhea or constipation, nausea or vomiting, abdominal pain or discomfort, gas, dry mouth, and dizziness. To help manage these, drink plenty of water, avoid foods that may cause gas, eat fiber-rich foods, and rest if you experience lightheadedness.

• Safety Related Concerns of Pentate Dsr Capsule:

Pregnancy

If you are pregnant or planning to become pregnant, consult your doctor to determine if Pentate Dsr Capsule is safe for you to take.

Breastfeeding

Breastfeeding mothers are advised to avoid Pentate Dsr Capsule as it may pass through breast milk and can cause side effects in breastfed babies. Therefore, it is important to consult your doctor before taking Pentate Dsr Capsule while breastfeeding.

Alcohol

Although no direct interaction between Pentate Dsr and alcohol has been found, but alcohol can increase stomach acid, worsen acid reflux, and increase the risk of side effects such as dizziness and irregular heartbeat. Therefore, it's advisable to avoid alcohol while undergoing treatment.

Food or Interactions with Other Medicines

Avoid spicy or junk foods, citrus foods (Like oranges, lemons, grapefruits, acidic foods (tomatoes), high-fat foods, carbonated drinks (soda) while taking Pentate Dsr Capsule.

Consult your doctor if you are taking any herbal products or supplements while taking Pentate Dsr Capsule. As always, it is a good idea to consult your doctor or healthcare provider about your specific dietary needs while on Pentate Dsr Capsule.

Driving

If you experience side effects such as dizziness or blurred vision, you should avoid driving or operating machinery while taking Pentate Dsr Capsule.

• Storage Instructions of Pentate Dsr Capsule:

Store protected from moisture, at a temperature not exceeding 25°C.

Keep Pentate Dsr Capsule out of reach of children.

Note: Eating smaller, more frequent meals and maintaining a healthy diet can help improve your condition.

Frequently Asked Questions (FAQs) about Pentate Dsr Capsule:

1. What is Pentate Dsr Capsule used for?

Pentate Dsr Capsule is used to manage conditions such as gastroesophageal reflux disease (GERD), acid reflux, peptic ulcers, and indigestion. It works by lowering stomach acid production, which helps alleviate symptoms like heartburn and discomfort. Additionally, it enhances gastric motility, promoting better digestion. This combination helps in providing relief from acid-related conditions and improving overall digestive health.

2. What is the ideal time to take Pentate Dsr Capsule – before food or after food?

Take Pentate Dsr Capsule with or without food, as recommended by your doctor based on your condition. However it is usually recommended to be taken before food, preferably 30 minutes to 1 hour prior to a meal. This helps the medication work better by lowering stomach acid before food arrives in the stomach. Always follow your doctor's instructions regarding timing for the best results.

3. Can Pentate Dsr Capsule be taken daily?

Typically Pentate Dsr Capsule can be taken daily preferably on an empty stomach, but the exact dosage may vary depending on your condition. It is important to follow your doctor’s advise and never take more than the recommended dose.

4. Which is better, Pentate Dsr or Pan 40?

The choice between Pan 40 and Pentate Dsr depends on your specific condition. Pan 40 contains Pantoprazole and is used primarily for treating acid-related issues like acid reflux and GERD. On the other hand, Pentate Dsr combines Pantoprazole with Domperidone, which not only reduces stomach acid but also helps with gastric motility and prevents nausea. Your doctor will recommend the most suitable medication based on your symptoms and needs.

5. Are there any specific dietary restriction while taking Pentate Dsr Capsule?

Yes, while using Pentate Dsr Capsule, it’s recommended to avoid spicy, oily, or fatty foods, as well as caffeine-containing beverages like coffee and tea, carbonated drinks, and acidic foods such as citrus fruits and vegetables. For better dietary guideline, consult a registered dietitian or physician who can provide personalized guidance based on your specific condition.

6. Is Pentate Dsr Capsule safe for gastritis treatment?

Pentate Dsr Capsule may be used to treat gastritis, depending on the underlying cause and severity of the condition. It contains Pantoprazole, which reduces stomach acid production, and Domperidone, which aids in gastric motility and helps alleviate nausea and bloating. If gastritis is caused by excessive stomach acid or delayed gastric emptying, Pentate Dsr can help by addressing both issues.

References:

1. Package leaflet: Information for the user Pantoprazole & Domperidone gastro-resistant Tablets (20 mg + 10 mg) PANSA D. Accessed on 18.03.2025. Click Here

2. Prescribing Information. Brand Name: P-RD® Capsules. Last Revised: February, 2023. Accessed on 18.03.2025. Click Here

3. Prescribing Information Leaflet. QPDOM. Accessed on 18.03.2025. Click Here

4. Prescribing Information Leaflet. PANSPED D. Last Revised: June 2020. Accessed on 18.03.2025. Click Here