MEDICINE OVERVIEW OF Pentab 40 mg Tablet (10 Tab)

THERAPEUTIC CLASS OF Pentab 40 mg Tablet (10 Tab)

WHY Pentab 40 mg Tablet (10 Tab) IS PRESCRIBED

Substitutes for - Pentab 40 mg Tablet (10 Tab)

HOW IT WORKS

HOW TO TAKE

WHEN TO TAKE

Pentab 40 mg Tablet (10 Tab) Warnings

Precautions of Pentab 40 mg Tablet (10 Tab)

Contraindications of Pentab 40 mg Tablet (10 Tab)

Side Effects of Pentab 40 mg Tablet (10 Tab)

Alcohol Interaction

Food to Avoid

Pregnancy/Lactation Protocol

Storage of Pentab 40 mg Tablet (10 Tab)

Pentab 40 mg Tablet (10 Tab)

Manufactured By: Alembic Pharmaceuticals Ltd.(Gd)
Composition/Salt

Pantoprazole 40mg

Pentab 40 Tablet Overview:

Pentab 40 Tablet is prescribed for the treatment of heartburn and acid indigestion associated with gastroesophageal reflux disease (GERD). Acid reflux or GERD is a common digestive condition nowadays, where stomach acid backs up into the esophagus (food pipe), causing a burning sensation in the chest (known as heartburn), and discomfort from indigestion when the acid irritates the stomach lining or throat. If left untreated, this condition can damage the esophagus due to excessive acid. By reducing stomach acid production, Pentab 40 helps alleviate symptoms and supports the healing and prevention of gastric and duodenal ulcers. Pentab 40 Tablet plays a vital role in managing acid-related digestive disorders, ensuring long-term relief.

Composition of Pentab 40 Tablet:

Each enteric coated Pentab 40 Tablet contains: Pantoprazole Sodium Sesquihydrate equivalent to Pantoprazole 40 mg and Excipients q.s.

Colours: Titanium Dioxide & Yellow Oxide of Iron.

Uses and Benefits of Pentab 40 Tablet:

Pentab 40 Tablet is commonly prescribed for the following conditions:

  • Reducing stomach acid production to alleviate symptoms associated with Gastroesophageal Reflux Disease (GERD) such as heartburn, indigestion, a sour taste in the mouth, pain and difficulty in swallowing.
  • Healing peptic ulcers.
  • Providing relief from hyperacidity symptoms such as stomach pain and discomfort.
  • Treating Zollinger-Ellison Syndrome, a condition where the stomach overproduces acid.

In combination with antibiotics, Pentab 40 Tablet helps treat Helicobacter pylori bacterial infections.

How Pentab 40 Tablet Works:

Pentab 40 Tablet contains the active ingredient Pantoprazole. Pantoprazole belongs to the group of medicines called, Proton Pump Inhibitor (PPI) that works by blocking the proton pump in the stomach lining, which is responsible for producing gastric acid. By inhibiting this enzyme, it effectively reduces stomach acid production, helping to treat conditions like GERD, acid reflux, and peptic ulcers.

Dosage of Pentab 40 Tablet:

  • Usage Direction

Take Pentab 40 Tablet exactly as your doctor prescribes, and follow the recommended dosage and schedule. Pentab 40 should be swallowed as a whole without crushing, chewing, or breaking it, and ideally at the same time each day. Do not stop or alter the dose of Pentab 40 Tablet without consulting your doctor, as this may prevent you from achieving the desired outcome. Ask your doctor or pharmacist to explain any administration procedure that you do not understand.

  • Missed Dose

If you miss a dose of Pentab 40 Tablet, take it as soon as it is remembered. If it is time for your next dose of Pentab 40 Tablet, skip the missed dose and resume your regular schedule. Avoid taking two doses to compensate for a missed one.

  • Overdose

If you accidentally take Pentab 40 Tablet more than your prescribed dose, seek immediate medical attention, as this may lead to serious side effects.

Contraindications of Pentab 40 Tablet:

If you are allergic to pantoprazole or any of its ingredients, do not take Pentab 40 Tablet. It should also be avoided if you are allergic to any other proton pump inhibitors, antibiotics, or any antiviral medication (atazanavir, or nelfinavir), or if you have cirrhosis, severe liver disease, or kidney disease.

Precautions & Warnings of Pentab 40 Tablet:

Before starting Pentab 40 Tablet, inform your doctor if you have jaundice, severe liver or kidney problems, or if you are at risk of low vitamin B12 levels and are receiving long term treatment with pantoprazole. Also, let your doctor know if you have a history of gastric ulcers or gastrointestinal surgery, or if you are taking HIV protease inhibitors like atazanavir. Additionally, notify your doctor if you have been on pantoprazole for more than 4 or more weeks or if you have experienced any skin reactions in the past.

Side Effects of Pentab 40 Tablet:

Pentab 40 Tablet may also cause some side effects, most of which do not require medical attention and typically go away as your body adapts to the medication. These may include headache, nausea, vomiting, gas, joint pain, diarrhea, and dizziness. However, if these side effects persist, consult your doctor as soon as possible. Some of the side effects may also be serious and may need medical attention such as: blistering, peeling, or bleeding skin, irregular or rapid heartbeat, muscle spasms, severe diarrhea with watery stools, changes in urination, blood in the urine, or worsening joint pain.

Safety Related Concerns of Pentab 40 Tablet:

  • Pregnancy

If you are planning to become pregnant or if a pregnancy is discovered, it's important to consult with your doctor to determine whether it is safe for you to continue with Pentab 40 Tablet.

  • Breastfeeding

Breastfeeding mothers are advised to avoid Pentab 40 Tablet as it may pass through breast milk and can cause side effects in breastfed babies. So, it is important to consult your doctor before taking Pentab 40 while breastfeeding.

  • Alcohol

Although no direct interaction has been found between Pentab 40 and alcohol, but alcohol can increase stomach acid which can irritate your stomach lining and worsen acid reflux, as well as increase the risk of side effects such as dizziness and irregular heartbeat. Therefore, it is recommended to avoid alcohol during treatment with Pentab 40.

  • Food or Interactions with Other Medicines

While taking Pentab 40 Tablet, avoid spicy or junk foods, citrus fruits (like oranges, lemons, and grapefruits), acidic foods (such as tomatoes), and high-fat foods. Additionally, cut down on caffeinated drinks like coffee and tea and carbonated beverages (soda), as they may irritate your stomach.

Consult your doctor if you are taking any herbal products or supplements while taking Pentab 40 Tablet. As always, please consult your doctor or healthcare provider about your specific dietary needs while on Pentab 40 Tablet.

  • Driving

If you experience side effects such as dizziness or blurred vision, you should avoid driving or operating machinery while taking Pentab 40 Tablet.

Storage Instructions of Pentab 40 Tablet:

Store protected from light and moisture at a temperature not exceeding 30°C.

Keep Pentab 40 Tablet out of reach of children.

Note: Eating smaller, more frequent meals, chewing your food slowly and properly, along with maintaining a healthy diet and managing your weight, can help improve your condition.

 

Frequently Asked Questions (FAQS) about Pentab 40 Tablet:

1. What is the use of Pentab 40 Tablet?

Pentab 40 Tablet is prescribed for the treatment of conditions caused by too much stomach acid, such as GERD, acid reflux, stomach ulcers, and Zollinger-Ellison syndrome. It works by reducing the amount of acid produced in your stomach. This helps relieve symptoms and promotes healing of the stomach lining, preventing further damage.

2. What is the best time to take Pentab 40 Tablet for maximum effectiveness?

To get maximum effectiveness, it is best to take Pentab 40 Tablet in the morning, or preferably 30 minutes to 1 hour before a meal. Taking it at least an hour before eating helps the medication reduce stomach acid production before food enters the stomach, allowing it to work more effectively. Always follow your doctor's instructions regarding timing for the best results.

3. Which is better, Pentab 40 or Pan D?

The choice between Pentab 40 and Pan D depends on your specific condition. Pentab 40 contains Pantoprazole and is used primarily for treating acid-related issues like acid reflux and GERD. On the other hand, Pan D combines Pantoprazole with Domperidone, which not only reduces stomach acid but also helps with gastric motility and prevents nausea. Your doctor will recommend the most suitable medication based on your symptoms and needs.

4. How should I take Pentab 40 Tablet?

Pentab 40 Tablets should be taken exactly as per your doctor's advice. Swallow Pentab 40 whole without crushing, chewing, or breaking it. The tablet has a coating that protects it from stomach acid and to ensure it works properly, this coating must not be broken. It is important to follow the specific timing recommended by your healthcare provider and not alter the dosage or frequency without consulting the doctor.

5. Is Pentab 40 Tablet an antacid?

No, Pentab 40 Tablet is not an antacid. It contains pantoprazole, which belongs to a class of medications called proton pump inhibitors (PPIs). Pentab 40 works by stopping the production of acid in the stomach lining, resulting in long lasting relief from conditions like GERD, acid reflux, peptic ulcers, heartburn and indigestion. On the other hand, antacids are made from compounds like calcium carbonate, aluminum hydroxide, magnesium hydroxide and sodium bicarbonate. These ingredients neutralize the existing stomach acid, providing quick but short term relief from symptoms like heartburn, duodenal, and gastric ulcers, etc.

6. Which is better for acidity- Rantac 150 and Pentab 40?

Both Rantac 150 and Pentab 40 are effective in managing acidity-related issues, but they serve slightly different purposes based on the severity of the condition. Rantac 150 contains ranitidine, which is typically suitable for mild or occasional acidity. On the other hand, Pentab 40 contains pantoprazole, which is more appropriate for frequent, chronic, or severe acid-related problems due to its longer lasting effect and stronger acid suppression. However, the choice between Rantac 150 and Pentab 40 should always depend on the individual’s specific health condition, the severity of symptoms, and how they respond to treatment. Please consult your healthcare professional before making any changes to your current medication.

 

References:

1. CDSCO. Pantoprazole. Click Here

2. MedlinePlus. Pantoprazole. Click Here

3. Pantoprazole Sandoz. Pantoprazole (as sodium sesquihydrate) enteric coated tablets. Consumer Medicine Information. Click Here

4. NHS. Pantoprazole -Brand name: Pantoloc Control. Click Here

5. Package leaflet: Information for the user. Pantoprazole 20mg Gastro-resistant Tablets. Pantoprazole (as sodium sesquihydrate). Click Here

6. Gallo, S., Dibildox, M., Moguel, A., Di Silvio, M., Rodríguez, F., Almaguer, I., & García, C. (1998). Superioridad clínica del pantoprazol sobre la ranitidina en la curación de la esofagitis por reflujo grado II y III. Estudio prospectivo, doble ciego, doble placebo. Experiencia clínica mexicana Grupo Mexicano de Estudio del Pantoprazol [Clinical superiority of pantoprazole over ranitidine in the treatment of reflux esophagitis grade II and III. A prospective, double-blind, double-placebo study. Mexican clinical experience. Mexican Pantoprazole Study Group]. Revista de gastroenterologia de Mexico, 63(1), 11–16. Click Here

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