Mesizole Capsule (10 Cap)

Mesizole Capsule Overview:

Mesizole Capsule is a combination medication designed to help with digestive issues caused by excess stomach acid. It contains two active ingredients: Rabeprazole, which reduces acid production in the stomach, and Domperidone, which helps food move more easily through the digestive system. This medicine is commonly prescribed to relieve symptoms like heartburn, nausea, bloating, and stomach pain associated with conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers. By addressing both acid production and digestive movement, Mesizole offers relief from discomfort and promotes better digestive health.

Composition:

Each hard gelatin capsule contains- Rabeprazole Sodium: 20 mg (As enteric coated pellets), Domperidone: 30 mg (as sustained release pellets) and Excipeints q.s.

Approved colours used in empty capsule shells.

Uses & Benefits of Mesizole Capsule:

• Mesizole Capsule is primarily used to treat conditions caused by excessive stomach acid, such as GERD, where acid flows back into the food pipe, causing heartburn and irritation.

• Mesizole Capsule is also helps with peptic ulcers, which are sores in the stomach or small intestine, and can ease symptoms like nausea, vomiting, bloating, and indigestion. The benefits include quick relief from burning sensations in the chest or throat, improved digestion, and reduced discomfort from gas or irregular bowel movements. By calming the stomach and improving food passage, it supports overall digestive comfort and helps people feel better during meals and daily activities.

Dosage of Mesizole Capsule:

• Usage Directions

Mesizole Capsule should be taken as prescribed by your doctor, typically 15-30 minutes before a meal, preferably in the morning, on an empty stomach. Swallow the capsule whole with water—do not crush, chew, or break it, as this can affect how the medicine works. The dosage and duration depend on your condition, age, and medical history, so follow your doctor’s instructions carefully. For best results, take it at the same time each day to maintain a consistent level of the medicine in your body.

• Missed Dose

If you forget to take a dose of Mesizole Capsule, take it as soon as you remember, unless it’s almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular schedule. Never take two doses at once to make up for a missed one, as this can increase the risk of side effects. If you frequently forget doses, consider setting a reminder or discussing with your doctor for better management.

• Overdose

Taking more than the prescribed dose of Mesizole Capsule can be harmful and may lead to symptoms like confusion, dizziness, sleepiness, anxiety, or even seizures in severe cases. If you suspect an overdose, contact your doctor immediately or visit the nearest hospital. To avoid accidental overdose, always stick to the prescribed dose and keep the medicine out of reach of children.

How Mesizole Capsule Works:

Mesizole Capsule combines two medicines that work together to tackle digestive issues. Rabeprazole, a proton pump inhibitor (PPI), blocks tiny pumps in the stomach lining that produce acid, reducing the overall acid level. This helps heal ulcers and prevents acid from irritating the food pipe. Domperidone, a prokinetic, speeds up the movement of food through the stomach and intestines by acting on dopamine receptors in the digestive tract. This reduces nausea, vomiting, and bloating, making digestion smoother and more comfortable.

Contraindications of Mesizole Capsule:

Mesizole Capsule should not be used by people who are allergic to Rabeprazole, Domperidone, or any other ingredients in the capsule. It’s also not suitable for individuals with severe liver or kidney problems, stomach or intestinal cancer, or certain heart conditions, as it may worsen these issues. Always inform your doctor about your medical history before starting this medicine to ensure it’s safe for you.

Precautions & Warnings of Mesizole Capsule:

Before taking Mesizole Capsule, tell your doctor about any existing health conditions, especially liver, kidney, or heart issues, or if you have a history of osteoporosis (weak bones). Long-term use may lead to low levels of magnesium, calcium, or vitamin B12, which can weaken bones or cause other health problems, so your doctor may recommend supplements or regular monitoring. Avoid smoking, as it can worsen acid-related issues. This medicine is not recommended for children under 12 years unless prescribed by a doctor. If you’re scheduled for an endoscopy, inform your doctor, as Mesizole may affect test results.

Side Effects of Mesizole Capsule:

Mesizole Capsule may cause side effects, though not everyone experiences them. Common ones include diarrhea, stomach pain, dry mouth, headache, dizziness, flatulence (gas), and weakness. These are usually mild and go away on their own. Less common side effects include flu-like symptoms, sleepiness, or changes in vision. If you notice severe symptoms like persistent diarrhea, dehydration, irregular heartbeat, or muscle cramps, contact your doctor immediately, as these could indicate more serious issues like low magnesium levels.

Pregnancy:

Mesizole Capsule is generally not recommended during pregnancy, as animal studies suggest potential harm to the developing baby, and human data is limited. If you’re pregnant or planning to become pregnant, consult your doctor to weigh the benefits against the risks. Your doctor may suggest safer alternatives to manage your symptoms during pregnancy.

Breastfeeding:

This medicine may pass into breast milk in small amounts, which could potentially affect the nursing baby. If you’re breastfeeding, talk to your doctor before taking Mesizole Capsule. They may recommend stopping breastfeeding, closely monitoring the baby for side effects, or switching to a different medication.

Food Interactions:

To get the best results from Mesizole Capsule, avoid spicy, fried, or fatty foods, as these can trigger acid reflux and worsen symptoms. It’s also a good idea to cut down on acidic foods like citrus fruits or tomatoes and caffeinated drinks like coffee or tea, which can irritate the stomach. Eating smaller, more frequent meals and avoiding late-night snacks can help improve the medicine’s effectiveness and reduce discomfort.

Drug Interaction:

Mesizole capsule contains rabeprazole (a proton pump inhibitor) and domperidone (a prokinetic). It may interact with several drugs. Rabeprazole can reduce the absorption of medications that require stomach acid, such as ketoconazole, itraconazole, and iron supplements. Domperidone can interact with drugs that prolong the QT interval (e.g., amiodarone, fluconazole, clarithromycin), increasing the risk of serious heart rhythm problems. Combining Mesizole with antacids or other acid-reducing agents may alter its effectiveness. Always consult a doctor before combining it with other medications.

 Alcohol:

Drinking alcohol while taking Mesizole Capsule is not advised, as it can increase stomach acid production, worsen heartburn, and reduce the medicine’s effectiveness. Excessive alcohol may also increase the risk of side effects like dizziness or stomach irritation. Consult your doctor about safe alcohol consumption while on this medication.

Drive & Using Machinery:

Mesizole Capsule may cause dizziness, sleepiness, or blurred vision in some people. If you experience these side effects, avoid driving, operating heavy machinery, or doing tasks that require focus until you know how the medicine affects you. If these symptoms persist, talk to your doctor about adjusting your treatment.

Storage of Mesizole Capsule:

Store in cool, dry & dark place. Protect from light and moisture.

Keep it out of reach of children and pets, and check the expiry date before use.  

Other Notes:

Do not stop taking the medicine abruptly without consulting your doctor, even if you feel better, as this could cause symptoms to return. If you don’t notice improvement after 14 days of use, let your doctor know, as you may need further evaluation for other underlying conditions.

Frequently Asked Questions about Mesizole Capsule:

Q 1: What is Mesizole Capsule used for?

A: Mesizole Capsule is used to treat acid reflux (GERD), peptic ulcers, and symptoms like heartburn, nausea, bloating, and indigestion by reducing stomach acid and improving digestion.

Q 2: Can I take Mesizole Capsule with food?

A: No, it’s best to take Mesizole Capsule 15-30 minutes before a meal, preferably on an empty stomach, for maximum effectiveness. Food can reduce how well the medicine works.

Q 3: Is Mesizole Capsule safe for long-term use?

A: Long-term use (over a year) may increase risks like bone fractures or mineral deficiencies. Always use it under medical supervision, and your doctor may monitor your health regularly.

Q 4: Can I take Mesizole Capsule if I’m allergic to certain medicines?

A: If you’re allergic to Rabeprazole, Domperidone, or similar medicines, avoid Mesizole Capsule. Inform your doctor about any allergies to ensure it’s safe for you.

Q 5: Does Mesizole Capsule cause drowsiness?

A: Yes, it may cause drowsiness or dizziness in some people. Avoid driving or operating machinery if you feel these effects until you’re sure it’s safe.

Q 6: Can children take Mesizole Capsule?

A: Mesizole Capsule is not recommended for children under 12 years unless specifically prescribed by a doctor.