Megamentin DUO DS Oral Suspension 6.6 g/30 ml

• Megamentin DUO DS Oral Suspension Overview:

Megamentin DUO DS Oral Suspension is a combination antibiotic medication used for the short-term treatment of various bacterial infections. It is effective against infections in areas like the ears, lungs, sinuses, urinary tract, skin, and soft tissues, including dental, bones, and joints. Megamentin DUO DS Oral Suspension works by targeting and eliminating the bacteria responsible for these infections.

Composition of Megamentin DUO DS Oral Suspension :

Each 5ml of the reconstituted Megamentin DUO DS Oral Suspension contains- Amoxicillin Trihydrate equivalent to Amoxycillin 400 mg and Potassium Clavulanate Diluted equivalent to Clavulanic Acid 57 mg.

• Uses and Benefits of Megamentin DUO DS Oral Suspension:

Megamentin DUO DS Oral Suspension is used to treat a wide range of bacterial infections following:

• Upper respiratory tract infections- Middle ear and sinus infections and inflammation of tonsils
• Lower respiratory tract infections- Chronic obstructive pulmonary disease (COPD), pneumonia
• Urinary tract infections (UTIs)- Infection of bladder and kidney as well as inflammation of urethra
• Skin and soft tissue infections- Infections caused by cuts, bites, or other wounds, also dental abscesses
• Bone and joint infections- Osteomyelitis
• Intra-abdominal Infections- Appendicitis, inflammation of the peritoneum.

• How Megamentin DUO DS Oral Suspension Works:

Megamentin DUO DS Oral Suspension contains two active ingredients, Amoxicillin and Clavulanic acid, that work together as a combination antibiotic to treat bacterial infections.

Amoxicillin is an antibiotic medicine, belongs to the beta-lactam class of medication, that stops the growth of infections causing bacteria by preventing them from forming their protective outer layer. While Clavulanic acid belongs to the class of medicines called ‘beta-lactamase inhibitors’ that helps amoxicillin work better. It works by blocking an enzyme called beta-lactamase, which some bacteria produce to protect themselves. Beta-lactamase can break down amoxicillin, making it ineffective, thereby allowing amoxicillin to work properly.

• Dosage of Megamentin DUO DS Oral Suspension:

Usage Direction

Take Megamentin DUO DS Oral Suspension exactly as prescribed by your doctor, and follow the recommended dosage and schedule. The syrup is provided in a dry powder form along with sterile water for reconstitution. First, shake the bottle to loosen the powder. Then, open the vial of sterile water included in the package, and add half of the water to the bottle. Secure the cap tightly and shake the bottle vigorously. Check visually to ensure the powder has fully dissolved and the mixture is well reconstituted. Do not stop or alter the dose of Megamentin DUO DS Oral Suspension without consulting your doctor, as this may prevent you from achieving the desired result. Ask your doctor or pharmacist to explain any administration procedures you do not understand.

Missed Dose

If you miss a dose of Megamentin DUO DS Oral Suspension , take it as soon as it is remembered. If it is time for your next dose of Megamentin DUO DS Oral Suspension , skip the missed dose and resume your regular schedule. Avoid taking two doses to compensate for a missed one.

Over Dose

If you accidentally take Megamentin DUO DS Oral Suspension more than your prescribed dose, seek immediate medical advice, as this may lead to serious side effects.

• Contraindications of Megamentin DUO DS Oral Suspension:

Do not take Megamentin DUO DS Oral Suspension if you are allergic to Amoxicillin, Clavulanic acid, other penicillins or cephalosporins, or any other ingredients of this medicine. Megamentin DUO DS Oral Suspension should be avoided if you have ever had liver problems or jaundice when taking an antibiotic.

• Precautions & Warnings of Megamentin DUO DS Oral Suspension:

Before starting Megamentin DUO DS Oral Suspension, inform your doctor if you have glandular fever (mononucleosis), Clostridium difficile associated diarrhea (CDAD), skin rash in patients with mononucleosis, or are being treated for liver or kidney problems.

• Side Effects of Megamentin DUO DS Oral Suspension :

Megamentin DUO DS Oral Suspension may cause some side effects, most of which do not require medical attention and typically go away as your body adjusts to the medication. However, if these effects persist, consult your doctor. These may include; diarrhea, upset stomach, vomiting, vaginal itching and/or discharge. To help manage these, drink plenty of water, avoid foods that may cause gas, eat fiber-rich foods, and rest if you experience lightheadedness. Some severe side effects may also occur which need medical attention such as liver inflammation, black hairy tongue, dark urine or pale stools, severe stomach cramps, severe watery or bloody diarrhoea.

• Safety Related Concerns of Megamentin DUO DS Oral Suspension:

Food or Interactions with Other Medicines

Avoid dairy based and calcium riched foods such as milk, cheese, yogurt or butter as well as citrus fruits like orange and grapefruit while taking Megamentin DUO DS Oral Suspension .

Consult your doctor if you are taking any herbal products or supplements while taking Megamentin DUO DS Oral Suspension. As always, it is a good idea to consult your doctor or healthcare provider about your specific dietary needs while on Megamentin DUO DS Oral Suspension .

• Storage Instructions of Megamentin DUO DS Oral Suspension:

Store protected from moisture. After reconstitutionkeep in a refrigerator when not in use.

Keep out of reach of children.

Note: Consume healthy, easily digestible food and stay hydrated to help improve your condition.

Frequently Asked Questions (FAQs) about Megamentin DUO DS Oral Suspension:

1. What are the uses of Megamentin DUO DS Oral Suspension?

Megamentin DUO DS Oral Suspension is an antibiotic used to treat various bacterial infections. It helps with respiratory issues like pneumonia, bronchitis, and sinus infections, as well as urinary tract infections, ear infections, and skin infections. It can also be used for bone and joint infections, stomach infections, and to prevent infections in patients with weakened immune systems or before surgery. Additionally, it treats heart valve infections (endocarditis) and gallbladder infections (cholecystitis).

2. Can Megamentin DUO DS Oral Suspension be used for viral infections?

No, Megamentin DUO DS Oral Suspension is an antibiotic medicine and is effective only against bacterial infections, not viral infections. It works by inhibiting the growth of infections-causing bacteria. It will not work for the common cold, flu, or other viral infections. For viral infections, antiviral medications may be required. Always seek advice from a healthcare provider for the correct treatment based on the type of infection. Do not self-medicate.

3. How does Megamentin DUO DS Oral Suspension work to treat bacterial infections?

Megamentin DUO DS Oral Suspension contains Amoxicillin and Clavulanic acid as its active ingredients to treat bacterial infections. Amoxicillin, a penicillin-type antibiotic, works by preventing bacteria from forming their protective outer layer, stopping their growth. On the other hand, Clavulanic acid, a beta-lactamase inhibitor, enhances amoxicillin’s effectiveness by blocking the beta-lactamase enzyme that some bacteria produce to protect themselves.

4. Why it is important to complete the course of Megamentin DUO DS Oral Suspension?

Depending on your condition, the treatment should last 7-14 days. It is essential to complete the full course of Megamentin DUO DS Oral Suspension, even if you start to feel better, for several important reasons:

Stopping the medication in between treatments may leave some bacteria alive, and those bacteria may multiply, causing the infection to return.

Incomplete courses of antibiotics (Megamentin DUO DS Oral Suspension ) can lead to bacteria becoming resistant, which are difficult to treat and can spread.

Completing the full course of Megamentin DUO DS Oral Suspension ensures all harmful bacteria are killed, preventing stronger strains from developing.

5. How many times a day I should take Megamentin DUO DS Oral Suspension?

The exact dose of Megamentin DUO DS Oral Suspension will depend on the severity of your infection, as prescribed by your doctor. Typically, it is taken every 8 hours (3 times a day) or every 12 hours (2 times a day). Always follow your doctor's instructions regarding the dosage and frequency. This ensures the medication is effective in treating your infection.

6. Can I take Megamentin DUO DS Oral Suspension together with other medications?

Before taking Megamentin DUO DS Oral Suspension,it is important to consult your doctor if you are taking other medications, such as blood thinners (e.g., Warfarin), or antacids. In some cases, it can make birth control pills less effective. So informing your doctor about any other drugs you're taking is crucial.

Reference:

1. AUGMENTIN BD TABLETS. Amoxicillin trihydrate - Potassium clavulanate. Last Revised: January 18, 2013. Accessed on: 24.03.2025. Click Here

2. Mother To Baby | Fact Sheets [Internet]. Brentwood (TN): Organization of Teratology Information Specialists (OTIS); 1994-. Amoxicillin and Clavulanic acid. 2024 Mar. Click Here

3. Langford, B. J., & Morris, A. M. (2017). Is it time to stop counselling patients to "finish the course of antibiotics"?. Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC, 150(6), 349–350. Accessed on: 24.03.2025. Click Here