MEDICINE OVERVIEW OF Lyrica 75 mg Capsule (14 Cap)

THERAPEUTIC CLASS OF Lyrica 75 mg Capsule (14 Cap)

WHY Lyrica 75 mg Capsule (14 Cap) IS PRESCRIBED

Substitutes for - Lyrica 75 mg Capsule (14 Cap)

HOW IT WORKS

HOW TO TAKE

WHEN TO TAKE

Lyrica 75 mg Capsule (14 Cap) Warnings

Precautions of Lyrica 75 mg Capsule (14 Cap)

Contraindications of Lyrica 75 mg Capsule (14 Cap)

Side Effects of Lyrica 75 mg Capsule (14 Cap)

Alcohol Interaction

Food to Avoid

Pregnancy/Lactation Protocol

Storage of Lyrica 75 mg Capsule (14 Cap)

Lyrica 75 mg Capsule (14 Cap)

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Lyrica 75 mg Capsule Overview:

Lyrica 75 mg Capsule is a neuropathic analgesic and anticonvulsant medication used to treat neuropathic pain (such as diabetic neuropathy), fibromyalgia, and Generalized Anxiety Disorder (GDA) in adults. It is also used as an adjunctive treatment for epilepsy.

It contains Pregabalin, which works by calming overexcited nerves in the body to reduce pain signals and stabilize electrical activity in the brain.

Lyrica 75 mg Capsule is widely used to manage chronic pain caused by nerve damage and serves as a supportive therapy for managing certain types of seizures.

 

Composition:

Each hard gelatin capsule contains- Pregabalin: 75 mg and Excipients q.s.

Approved colors used in capsule shell: Titanium Dioxide, Red Oxide of Iron, Black Oxide of Iron.

 

Uses & Benefits of Lyrica 75 mg Capsule:

Lyrica 75 mg Capsule is primarily used to treat or manage:

  • Neuropathic Pain: Reduces chronic pain caused by nerve damage due to conditions like diabetes (diabetic neuropathy) or shingles (postherpetic neuralgia).
  • Fibromyalgia: Helps to manage widespread musculoskeletal pain, fatigue, sleep disturbances, and mood issues associated with this condition.
  • Partial Onset Seizures: Used as an adjunctive (add-on) therapy alongside other medications to control epilepsy in adult patients.
  • Generalized Anxiety Disorder (GAD): Helps to manage symptoms of chronic anxiety, providing relief from excessive worry and restlessness.

 

How Does Lyrica 75 mg Capsule Work:

Lyrica 75 mg Capsule contains Pregabalin, which belongs to a class of drugs known as gabapentinoids. It does not bind directly to GABA receptors but instead binds to a specific site (alpha-2-delta subunit of voltage-gated calcium channels) in the central nervous system. This action reduces the release of certain neurotransmitters (nerve chemicals) that send pain signals to the brain, effectively "calming" overactive nerves.

 

Dosage of Lyrica 75 mg Capsule:

  • Usage Direction

Take Lyrica 75 mg Capsule strictly according to your doctor’s instructions, following the prescribed dose and timing. Lyrica 75 mg Capsule should be swallowed whole with water and not be opened, chewed, or crushed, preferably at the same time each day. Do not stop or alter the dose of Lyrica 75 mg Capsule without consulting your doctor, as this may prevent you from achieving the desired outcome. If you are unsure about the administration procedures of Lyrica, consult with your doctor or pharmacist.

  • Missed Dose

If you miss a dose of Lyrica 75 mg Capsule, take it as soon as you remember on the same day. But, if it is almost time for your next scheduled dose, skip the one you missed and continue following your regular dosing schedule. Do not attempt to take two doses if you have forgotten one.

You can set reminders on your smartphone, keep drug organizer boxes, or use other audio-visual technologies to prevent missing a dose.

  • Overdose

If you accidentally take Lyrica 75 mg Capsule more than your prescribed dose, seek immediate medical advice, as this may lead to serious side effects or contact a poison control center. Symptoms may include sleepiness, mood changes, depression, seizure, confusion, or agitation.

 

Contraindications of Lyrica 75 mg Capsule:

Do not take Lyrica 75 mg Capsule if you are hypersensitive to Pregabalin, or any of its ingredients. Symptoms of allergic reactions include breathing difficulty, shortness of breath, swelling of face, lips, tongue, or throat, itching, rashes, or hives on skin. If any of the symptoms occur seek immediate medical advice.

Lyrica 75 mg Capsule is generally contraindicated for use in children and adolescents under 18 years of age, as the safety and efficacy in this age group have not been fully established.

 

Precautions & Warnings of Lyrica 75 mg Capsule:

Before starting treatment, inform your doctor if you have severe renal impairment, as dose adjustments are necessary. Use with extreme caution if you have heart problems, such as congestive heart failure, or diabetes; some diabetic patients may experience weight gain, requiring adjustments to their hypoglycemic medications.

The use of Lyrica 75 mg Capsule might raise the chances of having suicidal thoughts. Monitor for changes in mood or behaviour, drowsiness, sleepiness, temporary vision loss, and heart failure, especially in elderly patients. Also, it may cause swelling of the hands, legs, or feet (peripheral edema).

Report any changes in vision, including blurred vision, to your doctor immediately. Do not stop taking this medicine abruptly, as it can cause insomnia, nausea, and headache. Tapering must be done under the supervision of a medical professional.

 

Side Effects of Lyrica 75 mg Capsule:

Like all other medicines, Lyrica 75 mg Capsule also has some side effects, which are usually mild to moderate and adjust with the body over time. The most common side effects include dizziness, headache, somnolence (extreme sleepiness), and dry mouth. Patients may experience increased appetite, blurred vision, weight gain, constipation, diarrhea, nausea, swelling of the limbs (edema), and minor difficulties with physical coordination.

Some serious side effects may also occur and need immediate medical attention. These include confusion, severe mood swings, or breathing difficulties. Other notable concerns include increased blood pressure, a significant loss of appetite, muscle cramps, and changes in sexual health, such as loss of libido or erectile dysfunction. Monitoring for these symptoms is essential to ensure the medication remains safe and effective for your specific needs.

 

Safety Related Concerns of Lyrica 75 mg Capsule:

  • Pregnancy

If you are pregnant or planning to become pregnant, consult your doctor before taking Lyrica 75 mg Capsule. It is not recommended unless clearly necessary, as there is a possible risk of fetal harm.

  • Breastfeeding

It is advised to avoid using the Lyrica 75 mg Capsule while breastfeeding, as Pregabalin passes through breast milk and could potentially affect the breastfed child.

  • Alcohol

Avoid alcohol consumption while taking Lyrica 75 mg Capsule, as it significantly increases the sedative effects (dizziness and drowsiness) of the drug.

  • Food Interactions

There are no specific food items that interact with Lyrica 75 mg Capsule; it can be taken with or without food, although specific dietary choices may affect its effectiveness. Avoid high-fat meals because they may slightly delay absorption. Along with it, sugary foods may increase the risk of weight gain, while high-sodium foods can contribute to swelling (edema), which are common side effects of the medication.

  • Drug Interactions

Lyrica 75 mg Capsule can interact with various medications, either by compromising their effectiveness or increasing the risk of toxicity. Pregabalin, when taken with oxycodone (opioids), lorazepam (benzodiazepines), or ethanol (alcohol), increases the risk of coma and respiratory failure. Additionally, patients using ACE inhibitors for blood pressure or Pioglitazone for diabetes should be monitored closely for increased risks of facial swelling (angioedema) and fluid retention.

Always inform your healthcare provider and pharmacist about all medications you are taking, including prescription drugs, over-the-counter medications, vitamins, minerals, and herbal supplements, to avoid potential interactions.

  • Using Machinery & Driving

Do not drive or operate heavy machinery until you know how Lyrica 75 mg Capsule affects you, as it frequently causes dizziness and drowsiness.

 

Storage of Lyrica 75 mg Capsule:

Store protected from moisture, at a temperature not exceeding 30°C. Keep out of reach of children. Avoid using it after the expiry date, printed on the packaging. Dispose of expired or unused medication properly; do not throw it away casually.

 

Additional Information:

  • For neuropathic pain, engaging in light, regular physical activity such as walking, swimming, or yoga can significantly improve blood circulation to the extremities, which helps maintain nerve health and reduces the intensity of pain.
  • Maintaining a healthy weight reduces the physical pressure on damaged nerves, particularly in the lower back and legs.
  • Strict monitoring and control of blood glucose levels are the most critical steps in preventing the progression of diabetic neuropathy. High sugar levels act as a toxin to nerve fibers over time.
  • Since nerve damage can reduce sensation, perform daily foot checks for minor cuts or blisters that you might not feel, as these can lead to serious infections.
  • Maintain a consistent sleep schedule. Sleep deprivation is a known trigger for electrical instability in the brain and can increase the frequency of seizures.
  • Identify and avoid personal triggers such as flashing lights, extreme stress, or certain sensory overloads.
  • Ensure adequate intake of Vitamin B12 (found in fish, meat, and dairy) or consider a supplement under medical advice, as this vitamin is essential for repairing the protective myelin sheath around the damaged nerves.
  • Drink plenty of water to help manage the common side effect of dry mouth and to support kidney function while processing the medication.
  • Do not share your medicine with someone else having the same symptoms as you, as the drug requires a prescription.

 

Frequently Asked Questions (FAQs):

 

Q. What is Lyrica 75 mg Capsule used for?

A. Lyrica 75 mg Capsule is primarily used for the treatment of neuropathic pain (nerve pain from diabetes or shingles), fibromyalgia, Generalized Anxiety Disorder (GAD), and as an add-on treatment for partial onset seizures in adults.

 

Q. How long does it take for Lyrica 75 mg Capsule to start working?

A. While some patients feel an initial "calming" effect within a few days, it typically takes 1 to 2 weeks of consistent use to achieve full pain relief or seizure control.

 

Q. Can Lyrica cause memory issues or "brain fog"?

A. Yes, some patients report difficulty concentrating or mild confusion. If these symptoms interfere with your daily life, speak to your doctor about adjusting the timing or dosage of your medication.

 

Q. Can I stop taking the medicine if my pain goes away?

A. No, you should never stop taking this medication without your doctor’s advice. Doing so can cause "withdrawal symptoms" such as insomnia, nausea, anxiety, or a return of seizures. Your doctor will provide a schedule to gradually reduce (taper) the dose.

 

Q. Is Lyrica 75 mg Capsule a painkiller?

A. Lyrica 75 mg Capsule is a specific type of painkiller for nerve pain (gabapentinoid) that specifically targets the nervous system to dampen overactive pain signals. It does not work like Ibuprofen, Paracetamol, or Aspirin for typical aches or inflammation. It is highly effective for nerve-related pain but not typically used for common headaches or muscle strains.

 

Q. Does Lyrica 75 mg Capsule cause weight gain?

A. Yes, increased appetite and fluid retention are known side effects that can lead to weight gain. However, if you notice significant weight gain, it is essential to consult your doctor right away.

 

 

Reference:

 

1. Pregabalin Capsule. Package Leaflet. Last Revised: November 2022. Accessed on: 27th March 2026. Click Here

2. PREGABALIN GH (pregabalin) capsules. Consumer Medicine Information. Last Revised on: January 2021. Accessed on: 27th March 2026. Click Here

3. MEDICATION GUIDE. LYRICA (LEER-i-kah) (pregabalin). Last Revised: April 2010. Accessed on: 27th March 2026. Click Here

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