Jitothyro 25 Tablet (120 Tab)

Jitothyro 25 Tablet Overview:

Jitothyro 25 Tablet is a thyroid hormone replacement therapy indicated for the treatment of hypothyroidism (underactive thyroid) and other conditions characterized by thyroid hormone deficiency.

The active ingredient, Thyroxine Sodium (also known as Levothyroxine), is a synthetic form of the thyroxine hormone (T4). By restoring optimal hormone levels, Jitothyro 25 Tablet helps regulate the body’s basal metabolic rate and maintain energy balance. It relieves systemic stress on the thyroid gland, effectively alleviating common symptoms such as fatigue, weight gain, and depression.

Additionally, stabilizing thyroid-stimulating hormone (TSH) levels, Jitothyro helps prevent the development or recurrence of goiters (enlarged thyroid gland).

However, it is important to note that Jitothyro 25 Tablet is strictly intended for hormone replacement therapy and must not be used as a treatment for obesity or for weight loss.

Composition:

Each uncoated tablet contains- Thyroxine Sodium Eq. to Anhydrous Thyroxine Sodium: 25 mcg and Excipients: q.s.

Colour: Sunset Yellow FCF.

Uses & Benefits of Jitothyro 25 Tablet:

Jitothyro 25 Tablet is primarily used for the following:

• Hypothyroidism: Treatment of an underactive thyroid (hypothyroidism), where the gland doesn't produce enough thyroid hormone.
• Hormone Replacement: It helps manage symptoms like fatigue, weight gain, depression, and sensitivity to cold by restoring hormone levels.
• Goiter Prevention: Used to treat or prevent goiter (enlarged thyroid gland) caused by hormonal imbalance. It reduces the over-stimulation of the thyroid gland by the pituitary hormone (TSH), thereby preventing glandular swelling.

How Does Jitothyro 25 Tablet Work:

Jitothyro 25 Tablet contains Thyroxine Sodium as its active ingredient. It is a synthetic version of the hormone thyroxine, which works by replacing the hormone your thyroid gland would normally produce.

Jitothyro 25 Tablet acts as an exogenous source of the hormone thyroxine (T4) and mimics the normal physiological process of the thyroid gland.

Once ingested, Thyroxine gets converted in the body into Triiodothyronine (T3). This hormone enters the body's cells and regulates energy production and metabolism, ensuring that your heart, brain, and muscles function correctly.

Dosage of Jitothyro 25 Tablet:

• Usage Direction

Take Jitothyro 25 Tablet strictly according to your doctor’s instructions, following the prescribed dose and timing. Jitothyro 25 Tablet should be swallowed as whole with water and not to be chewed, break, or crushed, preferably at the same time each day. Do not stop or alter the dose of Jitothyro 25 Tablet without consulting your doctor, as this may prevent you from achieving the desired outcome. If you are unsure about the administration procedures of Jitothyro, consult with your doctor or pharmacist.

• Missed Dose

If you miss a dose of Jitothyro 25 Tablet, take it as soon as you remember on the same day. But, if it is almost time for your next scheduled dose, skip the one you missed and continue following your regular dosing schedule. Do not attempt to take two doses if you have forgotten one. If you often forget to take your medication, consult with your doctor to re-evaluate your dosing schedule. Frequently missing doses could lead to undesired outcomes.

You can set reminders on your smartphone, keep drug organizer boxes, or use other audio-visual technologies to prevent missing a dose.

• Overdose

If you accidentally take Jitothyro 25 Tablet more than your prescribed dose, seek immediate medical attention or go to the nearest hospital for further advice. Symptoms of overdose may include fever, chest pain, restlessness, breathing difficulties, rapid or irregular heartbeat, rapid breathing, muscle cramps, headache, flushing, convulsions or paralysis.

Contraindications of Jitothyro 25 Tablet:

Do not take Jitothyro 25 Tablet if you are allergic to Thyroxine Sodium or any other ingredients of this medicine. Symptoms of severe allergic reactions may include red, itchy skin rashes, difficulty breathing, and swelling of the face or throat.

Patients with untreated adrenal gland disorders (such as Addison's disease) must avoid this medication. It is also contraindicated in cases of thyrotoxicosis (an overactive thyroid gland) that is not currently being managed, as well as during acute cardiovascular events, including a recent myocardial infarction (heart attack), active myocarditis, or pancarditis.

Additionally, during pregnancy, Jitothyro should not be used in combination with antithyroid medications to treat an overactive thyroid (thyrotoxicosis).

Precautions & Warnings of Jitothyro 25 Tablet:

Before taking Jitothyro 25 Tablet, it is vital to provide your healthcare provider with a complete medical history. Patients with a history of chronic hypothyroidism, particularly elderly individuals, should be monitored closely as they may be more sensitive to sudden hormonal shifts.

Extreme caution is required for those with underlying cardiovascular conditions, such as hypertension, angina, or coronary artery disease, as Thyroxine increases myocardial oxygen demand and may exacerbate cardiac stress.

In case of diabetic patients who are taking anti-diabetic medications, they require careful monitoring and adjustment of dosage, as Thyroxine can affect blood sugar levels. Additionally, taking high doses of Jitothyro for a long time can sometimes lead to weaker bones (osteoporosis), so exercise caution while taking the medicine.

Furthermore, your doctor will ask you to undergo regular blood tests to check your TSH (Thyroid Stimulating Hormone) levels.

Side Effects of Jitothyro 25 Tablet:

Jitothyro 25 Tablet may cause certain side effects, most of which are mild and temporary as the body adjusts to the medication. Stop taking the medicine and immediately seek medical help if you experience any of these- nausea, vomiting, diarrhea, headache, weight loss, fever, insomnia, menstrual irregularities, tremors, or irritability, and muscle cramps.

Some serious side effects may include palpitations or increased heart rate, chest pain, elevated blood pressure, sensitivity to the sun, joint pain, and severe allergic reactions (itching, hives, swelling of the face, tongue, or throat).

Safety Related Concerns of Jitothyro 25 Tablet:

• Pregnancy

Jitothyro 25 Tablet should be used with caution during pregnancy, as thyroid hormone requirements increase. If you are pregnant or planning to become pregnant, talk to your doctor before taking this medication for dose adjustments and to weigh the benefits against potential risks to the developing baby.

• Breastfeeding

If you are breastfeeding or planning to breastfeed, consult with your doctor before taking Jitothyro 25 Tablet. Because it may pass into breast milk in small amounts, medical guidance is necessary to ensure the safety of the breastfed child.

• Alcohol

There is no known direct pharmacological interaction between alcohol and Jitothyro 25 Tablet. However, healthcare providers generally advise limiting or avoiding alcohol consumption during treatment. Alcohol can worsen some side effects like headaches or palpitations.

• Food Interactions

The absorption of Jitothyro 25 Tablet is highly sensitive to certain dietary choices, which can significantly reduce its efficacy. High-fiber foods, soybean flour, and walnuts can bind to the medication in the gut, preventing it from being fully absorbed into the bloodstream. Similarly, grapefruit and grapefruit juice may interfere with the body's ability to process the hormone effectively. Therefore, it is often recommended to avoid such food items.

• Drug Interactions

Jitothyro 25 Tablet can interact with various medications, either by changing their effectiveness or increasing the risk of toxicity. It is crucial to inform your healthcare provider if you are taking anti-epileptic drugs, such as carbamazepine, phenytoin, primidone, and barbiturates.

Additionally, other medicines like antacids, sertraline, cimetidine, proton pump inhibitors, cholestyramine, colestipol, beta blockers, rifampicin, imatinib, corticosteroids, orlistat, ritonavir, sucralfate, amiodarone, oestrogen-containing medicines, androgen-containing medicines, and products containing St. John’s Wort could affect the efficacy of Thyroxine.

Furthermore, Jitothyro may affect the way certain medicines work, such as blood thinners (like Warfarin), insulin or other anti-diabetic medications, digoxin, tricyclic antidepressants, propanolol, ketamine, and NSAIDs.

Always inform your healthcare provider and pharmacist about all medications you are taking, including prescription drugs, over-the-counter medications, vitamins, minerals, and herbal supplements, to avoid potential interactions.

• Using Machinery & Driving

There is no significant impact on the ability to drive or operate machinery while taking Jitothyro 25 Tablet.

Storage of Jitothyro 25 Tablet:

Store protected from light & moisture. Store below 30°C. Keep the medicine out of reach of children.

Replace the lid tightly after use.

Avoid using it after the expiry date, printed on the packaging. Dispose of expired or unused medication properly; do not throw it away casually.

Additional Information:

• To enhance the effectiveness of Jitothyro 25 Tablet maintain a balanced diet rich in iodine. However, consult your healthcare provider before making significant dietary changes or taking iodine supplements, as excessive iodine can sometimes worsen certain thyroid conditions.
• Engaging in regular physical activity is highly beneficial. Exercise helps counteract common symptoms of hypothyroidism, such as a sluggish metabolism, weight gain, and low energy levels.
• Jitothyro must not be used for the treatment of obesity or for weight loss. In patients with normal thyroid function, taking thyroxine for weight loss is ineffective and can lead to life-threatening toxicity, especially when combined with other weight-loss drugs.
• If you take calcium, iron, or multivitamins, ensure they are taken at least 4 hours apart from your Jitothyro dose. These minerals can bind to the thyroid hormone in your stomach and prevent it from being absorbed.
• For the most accurate blood test results, it is often recommended to have your TSH levels checked in the morning before taking your daily dose of Jitothyro, or as specifically directed by your lab or physician.
• Do not suddenly stop your medication unless your doctor specifically tells you to.
• Do not share your medicine with someone else having the same symptoms as you, as the drug requires a prescription.

Frequently Asked Questions (FAQs):

Q. Why Jitothyro 25 Tablet is prescribed?

A. Jitothyro 25 Tablet is primarily prescribed for the management of hypothyroidism, a condition where the thyroid gland is under-active and unable to produce sufficient amounts of the hormone thyroxine.

Jitothyro acts as a hormone replacement therapy, restoring these levels to a healthy range (i.e., 5.0 to 12.0µg/dL). Additionally, it may be prescribed to help prevent the recurrence of an enlarged thyroid gland (goiter) or as part of the treatment plan for certain types of thyroid cancer.

Q. Can I stop taking Jitothyro once I feel better?

A. No, you should not stop taking Jitothyro 25 Tablet without consulting your doctor. Hypothyroidism is generally a chronic condition. When you begin to feel better, it is a sign that the medication is working effectively to restore your hormone levels—not that the condition has been "cured."

If you discontinue the medication, your thyroid hormone levels will drop again, causing symptoms such as extreme fatigue, weight gain, and depression to return. Your doctor will use periodic blood tests to ensure you remain on the correct dose for your long-term health.

Q. Can Jitothyro 25 Tablet be taken on an empty stomach?

A. Jitothyro 25 Tablet should be taken as prescribed by your physician. However, for optimal results, it is usually advised to take on an empty stomach, ideally at the same time each day. Because certain foods and beverages (like coffee) significantly prevent it from being absorbed into your bloodstream.

Q. Is it safe to take calcium or iron supplements at the same time as Jitothyro?

A. No. Calcium, iron, and even some multivitamins can significantly interfere with the absorption of thyroxine. To ensure the medication works correctly, you should wait at least 4 hours between taking your Jitothyro 25 Tablet and any supplements containing calcium or iron.

Q. Does Jitothyro 25 Tablet causes weight loss?

A. Jitothyro 25 Tablet is not a weight-loss medication, it is used to restore hormonal balance. Weight gain is a common symptom of an underactive thyroid due to a slowed metabolism. As the medicine restores your hormone levels, your metabolism improves, which can lead to weight stabilization or the loss of excess water weight.

However, if you experience significant or rapid weight loss, do not stop the medication abruptly. Instead, seek immediate medical advice, as your doctor may need to adjust your dose based on a blood test.