Jitoros CG 10/75 Capsule (10 Cap)

Jitoros CG 10/75 Capsule Overview:

Jitoros CG 10/75 Capsule is a combination medication primarily used for the prevention of heart attack, stroke, and chest pain, especially in people with narrowed or blocked arteries (atherosclerosis) or a high risk of blood clot formation.

High cholesterol and blood clots can block blood flow to vital organs and lead to serious problems, particularly in people with a history of heart attack, stroke, unstable angina, or other heart conditions.

Jitoros CG contains two active ingredients: Rosuvastatin and Clopidogrel. Rosuvastatin lowers ‘bad’ cholesterol (LDL) and helps reduce fatty plaque buildup in the arteries, while Clopidogrel prevents platelets from sticking together, thereby reducing the risk of harmful blood clots.

By improving blood flow and keeping arteries clear, Jitoros CG 10/75 Capsule helps lower the risk of future cardiovascular events and supports long-term heart and brain health when used along with a healthy diet and regular exercise.

Composition:

Each hard gelatin capsule contains- Rosuvastatin Calcium Eq. to Rosuvastatin (as light orange coloured film coated tablet): 10 mg, Clopidogrel Bisulphate eq. To Clopidogrel (as two light brown coloured film coated tablets each containing Clopidogrel Tablets 37.5 mg): 75 mg.

Rosuvastatin Colours: Sunset Yellow & Titanium Dioxide.

Clopidogrel Colours: Ferric Oxide Red & Titanium Dioxide.

Approved colours used in capsule shells.

Uses & Benefits of Jitoros CG 10/75 Capsule:

Jitoros CG 10/75 Capsule is primarily used for:

• Prevention of Major Cardiovascular Events: Reduces the risk of heart attack, stroke, or atherosclerotic arterial disease in patients with established conditions like Coronary Artery Disease (CAD) or Peripheral Artery Disease (PAD).
• Management of High Cholesterol (Hyperlipidemia): Effectively lowers "bad" cholesterol and triglycerides when used alongside lifestyle modifications.
• Reduction of Blood Clot Formation: Prevents dangerous clots in the arteries, particularly following procedures like stent placement and angioplasty, or after an episode of ACS.
• Secondary Stroke Prevention: Lowers the risk of a repeated stroke, specifically in patients with a history of cerebral ischemia (reduced blood flow to the brain).

How Does Jitoros CG 10/75 Capsule Work:

Jitoros CG 10/75 Capsule protects the heart and blood vessels through a dual-action mechanism by combining Rosuvastatin and Clopidogrel in a single formulation.

Rosuvastatin: Rosuvastatin belongs to the ‘statin’ class of drugs that help reduce cholesterol. It works by inhibiting an enzyme in the liver called HMG-CoA reductase, which is responsible for cholesterol production. As a result, it lowers "bad" LDL cholesterol and triglycerides levels, reduces the risk of plaque buildup in the arteries (atherosclerosis), and helps prevent heart-related issues like heart attacks and strokes.

Clopidogrel: Clopidogrel acts as an antiplatelet agent that works by blocking P2Y12 (ADP) receptors on platelet cell membranes. By preventing platelets from sticking together, it ensures blood flows smoothly through narrowed arteries and prevents the formation of life-threatening blood clots.

The synergistic combination provides robust cardiovascular protection by simultaneously preventing clot formation and maintaining healthy cholesterol levels.

Dosage of Jitoros CG 10/75 Capsule:

• Usage Direction

Take Jitoros CG 10/75 Capsule strictly according to your doctor’s advice, following the prescribed dose and timing. Jitoros CG 10/75 Capsule should be swallowed whole with water without crushing, chewing, or breaking, preferably at the same time each day. Do not stop or alter the dose of Jitoros CG 10/75 Capsule without consulting your doctor, as this may prevent you from achieving the desired outcome. If you are unsure about the administration procedures of Jitoros CG 10/75, consult with your doctor or pharmacist.

• Missed Dose

If you miss a dose of Jitoros CG 10/75 Capsule, take it as soon as you remember on the same day. But, if it is almost time for your next scheduled dose, skip the one you missed and continue following your regular dosing schedule. Do not attempt to take two doses if you have forgotten one. If you often forget to take your medication, consult with your doctor to re-evaluate your dosing schedule. Frequently missing doses could lead to undesired outcomes.

You can set reminders on your smartphone, keep drug organizer boxes, or use other audio-visual technologies to prevent missing a dose.

• Overdose

If you accidentally take Jitoros CG 10/75 Capsule more than your prescribed dose, seek immediate medical advice, as this may lead to serious side effects. Management of overdose could be through supportive care, such as monitoring liver enzymes or creatine kinase (CK) levels. Overdose prevention can be done by storing the medicine in a safe place and strictly following the prescribed doses.

Contraindications of Jitoros CG 10/75 Capsule:

Patients should avoid taking Jitoros CG 10/75 Capsule if they have a known allergy or hypersensitivity to rosuvastatin, clopidogrel, aspirin, other salicylates, other NSAIDs, or any of the inactive ingredients in the medication. Patients with active pathological bleeding conditions such as peptic ulcer disease, active gastrointestinal bleeding, or intracranial hemorrhage should not take this medication. Jitoros CG 10/75 Capsule is contraindicated in patients with haemophilia or other clotting disorders, gout, asthma, urticaria, rhinitis, active liver disease, unexplained persistent elevations in liver enzymes, or severe kidney issues.

The product is not to be used in children below 12 years of age except under medical supervision.

Precautions & Warnings of Jitoros CG 10/75 Capsule:

Before starting Jitoros CG 10/75 Capsule, it is crucial to consult your doctor if you have a history of liver or renal impairment, hypothyroidism, genetic muscular disorders, or alcohol abuse, as these conditions may require specific dose adjustments. While on this medication, regular monitoring of liver and kidney function, cholesterol levels, and Creatine Kinase (CK) levels is highly advisable. Because the medication contains Clopidogrel, you must inform your healthcare provider before any scheduled surgery or dental procedure, as the treatment may need to be temporarily suspended to manage bleeding risks. Additionally, seek immediate medical advice if you experience unexplained muscle pain, tenderness, or weakness, as these could be signs of a rare but serious muscle condition.

Side Effects of Jitoros CG 10/75 Capsule:

Jitoros CG 10/75 Capsule may cause side effects, though many are mild and temporary and improve as the body adjusts. Common side effects include headache, dizziness, nausea, stomach pain, indigestion, diarrhea or constipation, weakness, and fatigue. Some patients may notice mild muscle pain or cramps, easy bruising, or frequent nosebleeds due to its blood-thinning effect.

Serious side effects are uncommon but require immediate medical attention. These include severe or unexplained muscle pain, weakness, fever, or dark urine, which may indicate rhabdomyolysis. Signs of liver problems, such as yellowing of the skin or eyes, dark urine, persistent vomiting, or severe abdominal pain, should be reported promptly. Because Clopidogrel increases bleeding risk, seek urgent care for blood in stools or urine, vomiting blood, black stools, or bleeding that does not stop. Allergic reactions are rare but possible.

Safety Related Concerns of Jitoros CG 10/75 Capsule:

• Pregnancy

Jitoros CG 10/75 Capsule is generally not recommended during pregnancy. Rosuvastatin may harm the developing fetus by interfering with cholesterol synthesis, which is essential for fetal growth. If you discover you are pregnant while taking Jitoros CG, discontinue the medication immediately and contact your healthcare provider to discuss alternative treatment options.

• Breastfeeding

Taking Jitoros CG 10/75 Capsule while breastfeeding is not advisable, since the active ingredients of this medicine might be transmitted through breast milk and can cause side effects in breastfed babies. Hence, it is best to stop using Jitoros CG 10/75 Capsule during lactation and consult a healthcare professional if you are nursing to learn about any potential side effects of the drug during this period.

• Alcohol

Alcohol consumption should be limited or avoided while taking Jitoros CG 10/75 Capsule, as it can increase the risk of liver damage when combined with Rosuvastatin and may also raise the risk of bleeding due to Clopidogrel. Excessive or regular alcohol intake can worsen liver function, irritate the stomach lining, and increase the chance of gastrointestinal bleeding.

• Food Interactions

Jitoros CG 10/75 Capsule can be taken with or without food, as meals do not significantly affect the absorption of Rosuvastatin or Clopidogrel. Grapefruit and grapefruit juice should be avoided, as they can increase Rosuvastatin levels in the body and raise the risk of muscle-related side effects. For better cardiovascular health, patients should follow a heart-healthy diet that is low in saturated fats, trans fats, and cholesterol, and rich in fruits, vegetables, whole grains, lean proteins, and healthy fats. Limiting salt, fried foods, and sugary drinks further supports blood pressure and cholesterol control.

• Drug Interactions

Jitoros CG 10/75 Capsule can interact with various medications, either by compromising their effectiveness or increasing the risk of toxicity. Rosuvastatin is highly sensitive to certain HIV protease inhibitors, azole antifungals (e.g., itraconazole), and antibiotics like clarithromycin; these can cause the statin to reach dangerously high levels in the blood, significantly raising the risk of muscle damage (myopathy). Concomitant use with fibrates or niacin also necessitates dose adjustments to manage muscle-related risks. Additionally, antacids should be taken at least two hours apart to avoid lowering Rosuvastatin absorption. Regarding Clopidogrel, caution is required with medications that increase bleeding risks, such as Warfarin, NSAIDs (e.g., Ibuprofen), and SSRI/SNRI antidepressants. Notably, certain Proton Pump Inhibitors (PPIs) like omeprazole or esomeprazole can reduce Clopidogrel's antiplatelet activity, making it less effective at preventing clots. To ensure safety.

Always inform your healthcare provider and pharmacist about all medications you are taking, including prescription drugs, over-the-counter medications, vitamins, minerals, and herbal supplements, to avoid potential interactions.

• Using Machinery & Driving

Jitoros CG 10/75 Capsule generally has no significant impact on your ability to drive or operate machinery. However, individual reactions to medication can vary. If you experience side effects such as dizziness or fatigue, you should exercise caution and avoid these activities until you are sure about performing them safely.

Storage Instruction of Jitoros CG 10/75 Capsule:

Store protected from light and moisture, at a temperature not exceeding 25°C.

Keep Jitoros CG 10/75 Capsule out of reach of children.

Do not use Jitoros CG past its expiration date printed on the package. Dispose of expired or unused medications properly according to local guidelines or take them to a pharmacy take-back program.

Additional Information:

• Follow a heart-healthy diet rich in fruits, vegetables, whole grains, legumes, nuts, and fish.
• Limit salt, sugar, saturated fats, trans fats, and dietary cholesterol.
• Stay physically active.
• Maintain a healthy body weight.
• Quit smoking and avoid alcohol to improve treatment effectiveness.
• Monitor cholesterol levels regularly.
• Do not stop the medication without consulting your doctor, and never share your medicine with others, even if they have similar symptoms.

Frequently Asked Questions (FAQs)

Q. What is Jitoros CG 10/75 Capsule used for?

A: The Jitoros CG 10/75 Capsule offers a dual therapy approach with Rosuvastatin and Clopidogrel. This combination is effective in lowering bad cholesterol and triglyceride levels while also preventing blood clots in the arteries, ultimately reducing the risk of heart attacks and strokes.

Q. Can I stop taking Jitoros CG 10/75 Capsule if I feel better?

A: It is not advisable to stop taking Jitoros CG 10/75 Capsule suddenly, unless your healthcare provider suggests you do. Stopping the medication without direction could lead to an increased risk of harmful cardiac events.

Q. How long should I take Jitoros CG 10/75 Capsule?

A: Jitoros CG 10/75 Capsule can be suggested for long-term use to manage cholesterol level and prevent chronic cardiac conditions. Your doctor will evaluate whether to continue treatment for an extended period, considering your health status and any potential side effects from long-term use.

Q. Does Jitoros CG 10/75 Capsule cause weight gain?

A: Weight gain is a rare side effect of this medicine. However, consult your doctor if you notice sudden changes in your weight.

Q. What should I do if I notice blood in my urine or stool?

A: Immediately seek medical care if you observe blood in urine or stool because this may indicate the signs of internal bleeding. Stop taking Jitoros CG 10/75 Capsule, as it contains a blood thinner; it is crucial to be examined by a healthcare professional if any unusual internal or prolonged external symptoms occur without delay.

Q. Is Jitoros CG 10/75 Capsule safe for diabetic patients?
A: Yes, Jitoros CG 10/75 Capsule is safe for diabetic patients. However, it is essential to check your blood sugar levels closely. Rosuvastatin can occasionally cause a slight increase in blood glucose levels. Your doctor will weigh the benefit of heart protection against the need for potential adjustments to your diabetes medication.

Q. Can I take Jitoros CG 10/75 Capsule while I am on my period?

A: Yes, Jitoros CG 10/75 Capsule can usually be taken during your menstrual period. However, because this medicine contains Clopidogrel, which increases the risk of bleeding, some women may notice heavier or longer menstrual bleeding than usual. If you experience excessive bleeding, prolonged periods, or symptoms such as dizziness or weakness, you should contact your doctor. Do not stop the medicine on your own, especially if it has been prescribed to prevent heart attack or stroke.

Remarks:

1. Fixed Dose Combination (FDC) of Rosuvastatin 10 mg & Clopidogrel 75 mg Capsules. ROSUKEM CV 10. Last Revised: 13th June 2016. Accessed on: 22nd January 2026. Click Here

2. Rosugrel. Clopidogrel + Rosuvastatin. Accessed on: 22nd January 2026. Click Here