Jitopru 2 Tablet (10 Tab)

Jitopru 2 Tablet Overview:

Jitopru 2 Tablet is a prescription medicine used to treat chronic idiopathic constipation (CIC), a long-term constipation condition in adults who do not get enough relief from regular laxative treatment.

The active ingredient in Jitopru 2 is Prucalopride, which belongs to a class of medicines known as gastrointestinal prokinetics. It works by targeting the muscle walls of the gut to stimulate natural bowel movements and restore normal digestive motility, and making stools much easier to pass.

Composition:

Each film coated tablet contains- Prucalopride Succinate Equivalent to Prucalopride: 2 mg.

Colours: Titanium Dioxide.

Uses & Benefits of Jitopru 2 Tablet:

The uses of Jitopru 2 Tablet includes:

Treats chronic idiopathic constipation (CIC) in adults when standard fiber or laxatives fail to work.

Promotes regular and complete bowel movements by naturally stimulating the digestive tract.

How Does Jitopru 2 Tablet Work:

Jitopru 2 Tablet contains Prucalopride, a selective 5-HT4 (serotonin) receptor agonist. Serotonin functions as a natural chemical messenger in the digestive system, playing a vital role in promoting digestive movement.

By binding to these specific receptors, the medication stimulates nerves in the intestinal walls, thereby enhancing gut motility and promoting coordinated muscle contractions (peristalsis). This process significantly speeds up the transit of stool through the colon, making bowel movements more frequent, natural, and much easier to pass.

Dosage of Jitopru 2 Tablet:

• Usage Direction

Take Jitopru 2 Tablet strictly according to your doctor’s instructions, following the prescribed dose and timing. Do not crush, chew, or break the tablet. Jitopru 2 Tablet should be swallowed whole with water, preferably at the same time each day. Do not stop or alter the dose of Jitopru 2 Tablet without consulting your doctor, as this may prevent you from achieving the desired outcome. If you are unsure about the administration procedures of Jitopru 2, consult with your doctor or pharmacist.

• Missed Dose

If you miss a dose of Jitopru 2 Tablet, take it as soon as you remember on the same day. But, if it is almost time for your next scheduled dose, skip the one you missed and continue following your regular dosing schedule. Do not attempt to take two doses if you have forgotten one. If you often forget to take your medication, consult with your doctor to re-evaluate your dosing schedule. Frequently missing doses could lead to undesired outcomes.

You can set reminders on your smartphone, keep drug organizer boxes, or use other audio-visual technologies to prevent missing a dose.

• Overdose

In case of an accidental or intentional overdose of Jitopru 2 Tablet, seek immediate medical attention or contact a poison control center right away. An overdose may cause severe diarrhea, headache, nausea, or abdominal cramps.

Because treatment is generally symptomatic and supportive, it is crucial to drink enough water if severe diarrhea occurs to prevent dangerous fluid loss and electrolyte imbalances.

Contraindications of Jitopru 2 Tablet:

Do not take Jitopru 2 Tablet if you have a known hypersensitivity or allergy to Prucalopride or any of the other ingredients in this medicine. Allergic symptoms may include breathing difficulties, hives or a skin rash, severe itching, and swelling of your face, lips, tongue, or throat.

Furthermore, this medication must not be used by individuals suffering from intestinal perforation or a mechanical bowel obstruction due to structural disorders of the gut wall. It is also strictly contraindicated for patients with severe inflammatory conditions of the intestinal tract, such as Crohn's disease, ulcerative colitis, toxic megacolon, or megarectum.

Additionally, because the safety and effectiveness of Jitopru 2 Tablet are not known in children, it should not be administered to pediatric patients unless recommended by a healthcare professional.

Precautions & Warnings of Jitopru 2 Tablet:

Before starting treatment with Jitopru 2 Tablet, it is essential to consult your healthcare provider, particularly if you have a medical history involving severe renal or kidney impairment.

You should also inform your doctor if you have other serious medical conditions, such as lung or heart disease, nervous system disorders, cancer, AIDS, or hormonal imbalances.

Although rare, it is important to monitor for any psychological changes, such as worsening depression or suicidal thoughts; if any unusual mood disturbances occur, contact your healthcare provider immediately.

Additionally, be aware that if you experience severe diarrhea while taking this medication, oral contraceptives may not be fully absorbed and could fail to work. In such cases, contact your physician to discuss an alternative and effective method of contraception.

Side Effects of Jitopru 2 Tablet:

Like all medicines, Jitopru 2 Tablet can cause side effects, although not everyone will experience them. The most common side effects typically occur within the initial days of starting treatment and usually subside as the body adjusts to the medication. These frequent symptoms include headaches, nausea, diarrhea, abdominal pain or cramps, dizziness, flatulence (gas), fatigue, and dyspepsia (disturbed digestion).

On the other hand, some uncommon but serious side effects may also occur. These include tremors, a pounding or irregular heartbeat, rectal bleeding, a significant increase in the frequency of urination (pollakiuria), and migraines.

Additionally, psychological changes such as sudden mood disturbances, worsening depression, or suicidal thoughts require immediate clinical evaluation. If any mild symptoms persist or worsen, or if you experience any of the serious side effects listed above, it is critical to stop the medication and consult your healthcare provider or seek emergency medical attention right away.

Safety Related Concerns of Jitopru 2 Tablet

• Pregnancy

Jitopru 2 Tablet is generally not recommended during pregnancy. Women of childbearing potential should use effective contraception while taking this medication. Consult your doctor to determine that the benefits clearly outweigh the potential risks.

• Breastfeeding

It is advisable to avoid the use of Jitopru 2 Tablet while breastfeeding, as the active ingredient, Prucalopride, is excreted in human breast milk. Breastfeeding mothers should consult with their healthcare provider before starting this medication; it should only be used if the physician determines that the potential benefits clearly outweigh the risks to the infant.

• Alcohol

While there is no direct, severe interaction between Jitopru 2 Tablet and alcohol. Though alcohol may overlap with the side effects of Prucalopride, leading to headache, dizziness, and gastrointestinal symptoms like nausea or dehydration. It is advisable to limit or avoid alcohol while taking Jitopru.

• Food Interactions

Jitopru 2 Tablet can be taken with or without food, as there are no known significant food-drug interactions that affect its absorption. However, to better manage your condition and enhance digestive health, it is beneficial to incorporate probiotic foods (like yogurt or fermented vegetables) and fiber-rich foodstuffs into your regular diet. Maintaining a consistent intake of these nutrients can support the medication's effectiveness in restoring natural bowel regularity.

• Drug Interactions

There are no known interactions between Jitopru 2 Tablet or other medicines. However, Ketoconazole, erythromycin, or cyclosporine may slightly increase Prucalopride levels in the body, though dose adjustments are rarely needed.

Always inform your healthcare provider and pharmacist about all medications you are taking, including prescription drugs, over-the-counter medications, vitamins, minerals, and herbal supplements, to avoid potential interactions.

• Using Machinery & Driving

Jitopru 2 Tablet may cause dizziness or fatigue, especially during the first few days of treatment. Do not drive or operate heavy machinery until you know how this medicine affects you.

Storage of Jitopru 2 Tablet:

Store in a dry place, at a temperature not exceeding 25°C. Protected from light.

Avoid using it after the expiry date, printed on the packaging. Dispose of expired or unused medication properly; do not throw it away casually. Keep out of reach of children.

Additional Information:

• To enhance the effectiveness of Jitopru 2 Tablet increase dietary fiber. Gradually add more fiber-rich foods to your diet, such as whole grains, fruits (like prunes and apples), vegetables, and legumes.
• Drink plenty of fluids to help soften stools, unless restricted by a medical condition.
• Engage in daily physical activity to help stimulate intestinal contractions naturally.
• Dedicate a specific, unhurried time each day for bowel movements, preferably after a meal when the colon is most active. Do not ignore the urge to pass stool.
• Do not suddenly stop your medication unless your doctor specifically tells you to.
• Do not share your medicine with someone else having the same symptoms as you.

Frequently Asked Questions (FAQs):

Q. Why take Jitopru 2 Tablet?

A. Jitopru 2 Tablet is primarily prescribed to treat and manage Chronic Idiopathic Constipation (CIC) in adults. It is used when other treatments, such as lifestyle changes or standard laxatives, have not provided sufficient relief for long-term, persistent constipation.

Q. How long does it take for Jitopru 2 Tablet to start working?

A. The onset of action can vary from person to person. Your physician will monitor your progress and determine the appropriate duration of treatment; however, if your symptoms do not show significant improvement after four weeks, you should consult your healthcare provider for a clinical re-evaluation.

Q. Can I take Jitopru 2 Tablet every day?

A. You should take Jitopru 2 Tablet exactly as directed by your physician. The frequency and duration of your treatment are determined by your healthcare provider based on your individual medical profile. It is essential to strictly follow the dosing schedule they have prescribed for you and to consult them before making any changes to how you take the medication.

Q. What should I do if I get severe diarrhea while taking this medicine?

A. While mild and temporary diarrhea is a common side effect during the initial days of treatment, any progression to severe or persistent symptoms requires professional medical attention. If the diarrhea becomes intense, does not subside, or is accompanied by signs of dehydration, you should stop taking the medication and contact your doctor immediately. Your physician will provide specific guidance on managing fluid levels and determine whether the treatment remains appropriate for you.

Q. Can children take Jitopru 2 Tablet?

A. Jitopru 2 Tablet is primarily indicated for use in adults and is not recommended for children unless specifically evaluated and prescribed by a healthcare professional. Because its safety and efficacy have not been established in pediatric populations, the medication should always be stored securely and kept out of the reach of children.

Reference:

1. Prucalopride 1 mg & 2 mg film-coated tablets. Package Leaflet: Information for the User. Last Revised: November 2023. Accessed on: 29th May 2026. Click Here

2. Information for Patients prescribed Prucalopride (Resolor). Accessed on: 29th May 2026. Click Here

3. Prescribing Information. MOTEGRITY (prucalopride) tablets. Last Revised: December 2018. Accessed on: 29th May 2026. Click Here

4. Summary of Product Characteristics. Resolor 1 mg film-coated tablets (prucalopride). Last Revised: 6th June 2014. Accessed on: 29th May 2026. Click Here