Jitodydro 10 Tablet (10 Tab)

Jitodydro 10 Tablet Overview:

Jitodydro 10 Tablet is a hormonal medicine used to address hormonal imbalances and conditions caused by low progesterone levels (Progesterone deficiency) in the female body.

It is commonly prescribed for menstrual disorders, painful or irregular periods, endometriosis, infertility due to progesterone deficiency, threatened or recurrent miscarriage.

Jitodydro 10 Tablet contains dydrogesterone, a synthetic progestogen structurally identical to natural progesterone. It works by supplementing or replacing deficient progesterone in the bloodstream, helping to regulate the menstrual cycle and prepare the uterine lining for a healthy pregnancy.

Jitodydro 10 Tablet is also used in combination with estrogen as part of Hormone Replacement Therapy (HRT) for postmenopausal women, helping to relieve menopausal symptoms while protecting the uterine lining from overgrowth.

Composition:

Each film coated tablet contains- Dydrogesterone (Micronized): 10 mg and Excipients q.s.

Colour: Titanium Dioxide

Uses & Benefits of Jitodydro 10 Tablet:

Jitodydro 10 Tablet is prescribed for conditions associated with progesterone deficiency or hormonal imbalance:

• Dysmenorrhea (Painful Periods): Relieves severe menstrual cramps and abdominal discomfort.
• Secondary Amenorrhea & Irregular Cycles: Helps restore and regulate absent or irregular menstrual periods.
• Dysfunctional Uterine Bleeding (DUB): Prevents and stops abnormally or heavy bleeding.
• Female Infertility: Promotes the luteal phase of the menstrual cycle, supporting egg implantation for women who have luteal phase deficiency.
• Endometriosis: Reduces painful growth and inflammation of endometrial tissue outside the uterus.
• Recurrent or Habitual Miscarriage: Helps support and maintain the uterine lining during early pregnancy in women with low natural progesterone levels or a history of recurrent pregnancy loss.
• Premenstrual Syndrome (PMS): Alleviates mood swings, bloating, and physical distress before menstruation.
• Hormone Replacement Therapy (HRT): Used alongside estrogen therapy in postmenopausal women to protect the uterine lining from overgrowth (endometrial hyperplasia).

How Does Jitodydro 10 Tablet Work:

The active ingredient in Jitodydro 10 Tablet is Dydrogesterone, a synthetic form of progesterone that works by mimicking the body's natural progesterone.

After ovulation, naturally occurring progesterone prepares the inner lining of the uterus (endometrium) to receive and support a fertilized egg. By selectively binding to progesterone receptors in the uterus, Dydrogesterone transforms the uterine lining from its growth phase to a receptive phase, facilitating egg implantation, regulating the menstrual cycle, and halting abnormal uterine bleeding.

Dosage of Jitodydro 10 Tablet:

• Usage Directions

Take Jitodydro 10 Tablet strictly according to your doctor’s instructions, following the prescribed dose and timing. Jitodydro 10 Tablet should be swallowed whole with water and not chewed, cut, or crushed, preferably at the same time each day. Do not stop or alter the dose of Jitodydro 10 Tablet without consulting your doctor, as this may prevent you from achieving the desired outcome. If you are unsure about the administration procedures of Jitodydro 10, consult with your doctor or pharmacist.

• Missed Dose

If you miss a dose of Jitodydro 10 Tablet, take it as soon as you remember on the same day. But, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a forgotten tablet, as taking a extra dose can cause side effects. Please note that spotting or breakthrough bleeding may occur if a dose is missed.

If you often forget to take your medication, you can set reminders on your smartphone, keep drug organizer boxes, or use other audio-visual technologies to prevent missing a dose.

• Overdose

If you take Jitodydro 10 Tablet more than your prescribed dose, seek immediate medical advice or contact a poison control center immediately. Taking an accidental overdose may cause symptoms like severe nausea, vomiting, dizziness, or drowsiness.

Contraindications of Jitodydro 10 Tablet:

Do not take Jitodydro 10 Tablet if you have a known allergy or hypersensitivity to Dydrogesterone or any of the inactive components of this medication. It is strictly contraindicated in patients with severe liver disease, liver tumors, or active liver dysfunction, as well as those presenting with undiagnosed or unexplained abnormal vaginal bleeding.

Furthermore, this medicine must be avoided if you have a known, suspected, or history of progestin-dependent tumors, such as meningioma, breast cancer, or uterine cancer.

Additionally, if Jitodydro 10 Tablet is taken in combination with an estrogen for Hormone Replacement Therapy (HRT) to manage menopausal symptoms, all contraindications associated with estrogen therapy must also be evaluated and followed.

Precautions & Warnings of Jitodydro 10 Tablet:

Before starting Jitodydro 10 Tablet, it is essential to inform your healthcare provider of your complete medical history. Exercise caution if you have a history of blood clots, heart disease, stroke, porphyria, major depression, or mood disorders.

Headaches or migraines may develop during treatment, and light bleeding or spotting between menstrual cycles can occur initially; inform your doctor if this persists. Additionally, blood pressure may rise at the beginning of therapy, and rare conditions known to be influenced by sex hormones—such as severe itching (pruritus) or jaundice may be triggered.

Furthermore, when Jitodydro 10 is used to manage high-risk pregnancies or prevent miscarriage, routine clinical monitoring of both maternal and fetal health is essential.

Side Effects of Jitodydro 10 Tablet:

While taking Jitodydro 10 Tablet, you may experience side effects as your body adapts to the medication; these are typically mild and temporary. The most common side effects include nausea, vomiting, abdominal discomfort, headaches, migraines, breast tenderness, pain, or swelling, as well as changes in menstrual flow, such as unusually heavy or irregular periods, and breakthrough spotting.

However, seek immediate medical attention if you experience severe reactions such as allergic swelling or breathing difficulty, jaundice (yellowing of skin or eyes), or signs of a blood clot, such as sudden chest pain, breathlessness, or leg swelling.

Safety Related Concerns of Jitodydro 10 Tablet:

• Pregnancy

Jitodydro 10 Tablet is frequently prescribed during early pregnancy to provide luteal support or prevent recurrent miscarriages, but it must strictly be used under direct medical supervision. If you are pregnant, suspect you might be pregnant, or are planning to conceive, consult your physician to ensure the clinical benefits outweigh any potential fetal risks.

• Breastfeeding

It is recommended to avoid using Jitodydro 10 Tablet while breastfeeding. Small amounts of dydrogesterone may pass into breast milk, which could potentially affect the nursing infant.

• Alcohol

Alcohol consumption should be avoided while taking Jitodydro 10 Tablet. Alcohol can interfere with hormonal stability, strain liver function, and worsen side effects such as dizziness, drowsiness, or nausea.

• Food Interactions

There are no significant interactions between Jitodydro 10 Tablet and food. It can be taken with or without food, as directed by your physician, but taking it at consistent times with or after meals can minimize stomach discomfort.

If you have any known food allergies or dietary restrictions, inform your healthcare provider before starting the medication.

• Drug Interactions

Jitodydro 10 Tablet can interact with various medications, which may reduce its therapeutic effectiveness or alter drug clearance in the body.

Concomitant use of hepatic enzyme inducers—such as anticonvulsants (e.g., carbamazepine, phenobarbital, phenytoin), antibiotics and antifungals (e.g., rifampicin, rifabutin), antiretrovirals (e.g., nevirapine, efavirenz), and herbal supplements (e.g., St. John’s Wort)—can accelerate the metabolism of dydrogesterone, thereby decreasing its efficacy.

Always inform your healthcare provider of all prescription medications, over-the-counter drugs, and herbal supplements you are taking before starting treatment.

• Using Machinery & Driving

Jitodydro 10 Tablet may occasionally cause sleepiness or dizziness. Avoid driving or operating machinery until you know how the medication affects you.

Storage of Jitodydro 10 Tablet:

Store at a temperature not exceeding 25°C. Protect from light. Keep all medicines out of reach of children.

Do not use it once the expiration date on the packaging has been reached. Dispose of expired or unused medication properly; do not throw it away casually.

Helpful Tips:

• Eat a balanced diet rich in whole foods, fiber, lean protein, and healthy omega-3 fatty acids (nuts, seeds, olive oil) to support liver metabolism and hormonal balance.
• Moderate physical activity (e.g., walking, yoga, cycling) helps regulate endocrine function and improves insulin sensitivity, aiding conditions like PMS and menstrual irregularities.
• High stress elevates cortisol, which can disrupt reproductive hormones; prioritize adequate sleep and relaxation techniques.
• Take the medicine continuously for the exact number of days prescribed by your doctor.
• Do not stop taking your medication suddenly unless your doctor specifically instructs you.
• Do not share your medicine with someone else who has the same symptoms, as it is a prescription medication.

Frequently Asked Questions (FAQs):

Q: What is Jitodydro 10 Tablet used for?

A: Jitodydro 10 Tablet is a prescription medication containing dydrogesterone, a synthetic form of progesterone. It is used to treat conditions caused by progesterone deficiency in women, such as menstrual disorders, painful menstruation (dysmenorrhea), endometriosis, and female infertility, as well as to support early pregnancy and prevent recurrent miscarriages.

Q: Is Jitodydro 10 Tablet a contraceptive or birth control pill?

A: No, Jitodydro 10 Tablet is not a birth control pill and does not prevent pregnancy. Unlike many traditional contraceptives, dydrogesterone does not inhibit ovulation at therapeutic doses. In fact, it is frequently prescribed to support ovulation, improve the uterine lining, and help sustain early pregnancy in women with progesterone deficiencies.

Q: Does Jitodydro 10 Tablet cause weight gain?

A: Significant weight gain is uncommon with Jitodydro 10 Tablet. However, mild fluid retention, temporary bloating, or slight weight fluctuation can occasionally occur in some individuals due to normal hormonal changes during treatment. If you notice sudden or significant weight changes, consult your doctor.

Q: Can I stop taking Jitodydro 10 Tablet once my period starts?

A: No, do not stop taking the medication abruptly or alter your dosing schedule without consulting your gynecologist. Stopping early can trigger withdrawal bleeding, disrupt your menstrual cycle, or reduce the overall effectiveness of your treatment. Always follow your doctor's instructions on when to start and stop the medicine during each cycle.

Q: Is Dydrogesterone the same as natural Progesterone?

A: No, dydrogesterone is not identical to natural progesterone, but it is a synthetic progestogen that behaves very similarly in uterine tissue. It is designed to selectively bind to progesterone receptors, making it highly effective at lower oral doses while minimizing unwanted androgenic or estrogenic side effects.

Q: What should I do if I experience spotting while taking Jitodydro 10 Tablet?

A: Light spotting or breakthrough bleeding between cycles is a common side effect when starting hormonal therapy as your body adjusts. Continue taking the medication as prescribed, but inform your doctor if the bleeding becomes heavy or persists for an extended period.

References:

1. DUPHASTON. Film Coated Tablets. Prescribing Information. Last Revised: July 2014. Accessed on: 30th July 2026. Click Here

2. DYDROPREG. Dydrogesterone Tablets I.P. 10 mg. Last Revised: January 2022. Accessed on: 30th July 2026. Click Here

3. Duphaston 10mg film-coated tablets. Dydrogesterone. Package Leaflet: Information for the user. Last Revised: September 2025. Accessed on: 30th July 2026. Click Here

4. Dydrogesteron Lotus 10 mg filmomhulde tabletten. Dydrogesteron. Package Leaflet: Information for the user. Last Revised: December 2024. Accessed on: 30th July 2026. Click Here