Jitodiclo CXPA 50/500/325 Tablet (10 Tab)

Jitodiclo CXPA 50/500/325 Tablet Overview:

Jitodiclo CXPA 50/500/325 Tablet is a combination medicine used to relieve acute musculoskeletal pain associated with muscle spasms.

Jitodiclo CXPA 50/500/325 Tablet is effective in treating a wide range of painful musculoskeletal conditions, including back pain, neck pain, shoulder pain, sprains, strains, sports injuries, soft tissue injuries with muscle spasm, tendonitis, tenosynovitis, and bursitis.

It manages pain by combining three active ingredients- Diclofenac Potassium (a non-steroidal anti-inflammatory drug or NSAID), Paracetamol (an analgesic and fever reducer), and Chlorzoxazone (a central muscle relaxant).

These active ingredients work synergistically to target pain at its source. Diclofenac and Paracetamol block the production of specific chemical messengers (prostaglandins) that trigger pain and swelling. Simultaneously, Chlorzoxazone acts on the central nervous system to relieve muscle stiffness and spasms, improving blood flow to the affected area and restoring mobility.

Composition:

Each uncoated tablet contains- Paracetamol: 325 mg, Diclofenac Potassium: 50 mg and Chlorzoxazone: 500 mg.

Colour: Red Oxide of Iron.

Uses & Benefits of Jitodiclo CXPA 50/500/325 Tablet:

Jitodiclo CXPA Tablet is indicated for the short-term treatment and management of pain and muscle spasms caused by conditions such as:

• Musculoskeletal Pain & Spasms: Effective relief from acute lower back pain, neck pain, shoulder stiffness, and generalized muscle aches accompanied by spasms.
• Soft Tissue & Sports Injuries: Relieves discomfort and aids healing in cases of acute sprains, strains, and inflamed tendons or bursae (tendonitis, tenosynovitis, bursitis).
• Arthritic & Joint Disorders: Helps manage painful flare-ups of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis by reducing swelling and improving joint mobility.
• Post-Traumatic & Post-Operative Pain: Helps manage pain, swelling, and localized inflammation caused by surgical procedures, dental work, or sudden physical trauma.

How Does Jitodiclo CXPA 50/500/325 Tablet Work:

Jitodiclo CXPA 50/500/325 Tablet combines three active ingredients that work through different pathways to target pain, inflammation, and muscle tightness simultaneously.

Diclofenac Potassium is an NSAID that works by inhibiting cyclooxygenase (COX) enzymes and blocks the synthesis of prostaglandins—the primary chemical messengers responsible for pain and swelling.

Working alongside it, Paracetamol acts centrally within the brain as an analgesic and antipyretic, elevating the body's overall pain threshold and regulating body temperature.

Completing the combination, Chlorzoxazone is a central muscle relaxant that targets the spinal cord and the brain to inhibit multisynaptic muscle reflexes, effectively easing stiffness, relieving painful spasms, and restoring movement.

Together, these three agents deliver comprehensive and synergistic relief for complex musculoskeletal discomfort.

Dosage of Jitodiclo CXPA 50/500/325 Tablet:

• Usage Direction

Take Jitodiclo CXPA Tablet strictly according to your doctor’s instructions, following the prescribed dose and timing. Jitodiclo CXPA 50/500/325 Tablet should be swallowed whole with water and not chewed, cut, or crushed, preferably at the same time each day. Do not stop or alter the dose of Jitodiclo CXPA Tablet without consulting your doctor, as this may prevent you from achieving the desired outcome. If you are unsure about the administration procedures of Jitodiclo CXPA 50/500/325, consult with your doctor or pharmacist.

• Missed Dose

If you miss a dose of Jitodiclo CXPA 50/500/325 Tablet, take it as soon as you remember on the same day. But if it is almost time for your next scheduled dose, skip the missed one and continue following your regular dosing schedule. Do not take double doses if you have forgotten one.

If you often forget to take your medication, you can set reminders on your smartphone, keep drug organizer boxes, or use other audio-visual technologies to prevent missing a dose.

• Overdose

If you take Jitodiclo CXPA 50/500/325 Tablet more than your prescribed dose, seek immediate medical advice or contact a poison control center immediately. Symptoms of accidental overdose may include nausea, vomiting, headache, dizziness, abdominal pain, liver failure, and acute kidney failure.

Label Warning: Taking more than daily dose of Paracetamol may cause serious liver damage or allergic reactions (e.g. swelling of the face, mouth & throat, difficulty in breathing, itching or rash).

Contraindications of Jitodiclo CXPA 50/500/325 Tablet:

Do not take Jitodiclo CXPA 50/500/325 Tablet if you have a known severe allergy or hypersensitivity to Diclofenac, Paracetamol, Chlorzoxazone, any other NSAIDs, or any of the inactive ingredients in this formulation. Individuals with active peptic ulcers, gastrointestinal bleeding, or a history of recurrent ulceration must not use it.

Additionally, this medication should be avoided by patients suffering from severe heart failure, severe liver or kidney impairment, or those with a history of asthma, hives (urticaria), or acute rhinitis triggered by NSAID use.

Precautions & Warnings of Jitodiclo CXPA 50/500/325 Tablet:

Before starting Jitodiclo CXPA 50/500/325 Tablet, consult your healthcare provider and disclose your complete medical history. Special caution is required for patients taking concurrent medications that increase the risk of gastrointestinal ulceration or bleeding. Because this formulation contains Paracetamol, exceeding the recommended daily dose or consuming alcohol while on treatment significantly elevates the risk of severe liver damage.

Furthermore, prolonged use or high doses of NSAIDs like Diclofenac can cause serious stomach ulcers, bleeding, or perforation, as well as a slightly increased risk of heart attack or stroke.

Patients with a history of hypertension, fluid retention, or edema require close monitoring, while elderly patients necessitate added caution and potential dosage adjustments due to heightened susceptibility to adverse reactions.

Side Effects of Jitodiclo CXPA 50/500/325 Tablet:

The use of Jitodiclo CXPA 50/500/325 Tablet may cause side effects, most of which are mild and temporary as the body adjusts to the medication. Common side effects may include gastrointestinal discomfort such as nausea, vomiting, stomach upset, constipation, diarrhea, and loss of appetite, along with central nervous system reactions like dizziness, lightheadedness, drowsiness, headache, or mild cutaneous symptoms such as localized itching and skin rash.

However, you should seek immediate medical attention if you experience any serious side effects. These include severe abdominal pain, prolonged bleeding time, signs of acute liver failure, gastrointestinal perforation, severe blood dyscrasias, or life-threatening hypersensitivity reactions such as anaphylaxis, angioedema, and toxic epidermal necrolysis.

Safety Related Concerns of Jitodiclo CXPA 50/500/325 Tablet:

• Pregnancy

Jitodiclo CXPA 50/500/325 Tablet is generally not recommended during pregnancy, as the NSAID component (Diclofenac) can harm the fetus or lead to complications during delivery unless strictly prescribed by an obstetrician. If you are pregnant, suspect you might be pregnant, or are planning to conceive, consult your physician immediately to discuss safe alternative treatments.

• Breastfeeding

Jitodiclo CXPA 50/500/325 Tablet should be used with extreme caution and strictly under the supervision of a healthcare provider. It is not known whether the active ingredients pass into the breast milk and affect the nursing infant. It is recommended to discontinue the medication during lactation or consult a healthcare professional.

• Alcohol

Avoid drinking alcohol while taking Jitodiclo CXPA 50/500/325 Tablet. Combining alcohol with this medication can increase the risk of severe liver damage, gastrointestinal bleeding, and can enhance the sedative effects, leading to increased drowsiness, dizziness, and impaired motor control.

• Food Interactions

There are no known major food-drug interactions associated with Jitodiclo CXPA 50/500/325 Tablet. While it can be taken with or without food, taking this medication with or immediately after a meal is advised to minimize potential gastrointestinal irritation and stomach upset caused by Diclofenac.

If you have any known food allergies, dietary restrictions, or severe digestive issues, inform your healthcare provider before starting the medication.

• Drug Interactions

Jitodiclo CXPA 50/500/325 Tablet can interact with several medications, altering their effectiveness or increasing the risk of adverse side effects.

Concurrent use with anticoagulants (e.g., Warfarin) or other NSAIDs increases the likelihood of serious gastrointestinal bleeding and ulceration. Concomitant use with antihypertensives or diuretics may reduce their blood pressure-lowering effectiveness and compromise renal function.

Combining Jitodiclo CXPA 50/500/325 with central nervous system (CNS) depressants or alcohol intensifies drowsiness and sedation.

Additionally, notable interactions occur with immunosuppressants (ciclosporin, tacrolimus) due to heightened nephrotoxicity, as well as with lithium, digoxin, methotrexate, and cholestyramine, which may require careful therapeutic monitoring or dosage adjustments.

Always inform your healthcare provider of all prescription medications, over-the-counter drugs, and herbal supplements you are taking before starting treatment.

• Using Machinery & Driving

Jitodiclo CXPA 50/500/325 Tablet can cause drowsiness, dizziness, lightheadedness, or blurred vision. Avoid driving, operating heavy machinery, or performing tasks that require full mental alertness until you understand how the medication affects you.

Storage of Jitodiclo CXPA 50/500/325 Tablet:

Store protected from light and moisture, at a temperature not exceeding 30°C. Keep all medicines out of reach of children.

Do not use it once the expiration date on the packaging has been reached. It is important to dispose of expired or unused medications properly; do not throw it away casually.

Helpful Tips:

• Combine medication with adequate physical rest for muscle injuries.
• Apply ice packs for acute swelling and heat pads to relax stiff muscles.
• Start light stretching or physical therapy once acute pain subsides to rebuild strength and flexibility.
• Maintain adequate hydration, consume an anti-inflammatory diet rich in omega-3 fatty acids, antioxidants, and adequate protein to support muscle and tissue recovery.
• Avoid alcohol and high-sodium foods to reduce swelling and organ strain.
• Do not stop taking your medication suddenly unless your doctor specifically instructs you.
• Do not share your medicine with someone else who has the same symptoms, as it is a prescription medication.

Frequently Asked Questions (FAQs):

Q: Can I take Jitodiclo CXPA 50/500/325 Tablet for a simple headache?

A: No. Jitodiclo CXPA 50/500/325 Tablet is formulated with a muscle relaxant (Chlorzoxazone) alongside pain relievers to treat musculoskeletal pain and muscle spasms. Simple headaches should be treated with basic analgesics unless a physician specifically prescribes Jitodiclo CXPA for a tension-type or muscle-related headache.

Q: Is Jitodiclo CXPA 50/500/325 Tablet safe for long-term use?

A: No. Jitodiclo CXPA 50/500/325 Tablet is intended for short-term use only. Prolonged or unmonitored use significantly increases the risk of severe side effects, including liver toxicity (due to Paracetamol), stomach ulcers and gastrointestinal bleeding (due to Diclofenac), and kidney impairment. Always follow your doctor's prescribed duration and do not extend treatment without medical supervision.

Q: Can I take other Paracetamol-containing medicines along with Jitodiclo CXPA 50/500/325 Tablet?

A: No, Jitodiclo CXPA 50/500/325 Tablet already contains Paracetamol, taking it alongside other Paracetamol-containing products can easily result in an accidental overdose, leading to severe liver damage and allergic reactions (e.g. swelling of face, mouth and throat, difficulty in breathing, itching or rashes). Always check the active ingredients of any additional medication or consult your pharmacist before combining treatments.

Q: Does Jitodiclo CXPA 50/500/325 Tablet cause dependency?

A: Jitodiclo CXPA 50/500/325 Tablet is generally considered non-addictive and does not cause dependency. None of its active components, Diclofenac Potassium, Paracetamol, or Chlorzoxazone are controlled substances or opioids. However, it should be taken under strict medical supervision. If taken for a long period without medical guidance, patients may develop a psychological reliance on the medication for continuous pain relief. Physicians carefully monitor therapy to ensure the drug is used strictly for its intended short-term duration and that underlying causes of pain are appropriately managed.

Q: Is Jitodiclo CXPA 50/500/325 Tablet safe for children?

A: Jitodiclo CXPA 50/500/325 Tablet is generally not recommended for pediatric use without explicit medical evaluation. Because pediatric dosing for pain relievers and muscle relaxants depends strictly on a child's age, weight, and specific medical condition, you should never administer Jitodiclo CXPA 50/500/325 Tablet to a child unless a pediatrician specifically prescribes it and provides precise dosing instructions.

References:

1. Central Drugs Standard Control Organization (FDC Division). Chlorzoxazone + Paracetamol + Diclofenac. Accessed on: 6th August 2026. Click Here

2. Vivian MR. Chlorzoxazone, Diclofenac Sodium & Paracetamol Tablets. Accessed on: 6th August 2026. Click Here