Jitodef 6 Tablet (10 Tab)

Jitodef 6 Tablet Overview:

Jitodef 6 Tablet is an oral corticosteroid medicine, contains Deflazacort, used to treat inflammatory and autoimmune conditions where the immune system damages healthy tissues. It is commonly prescribed for Duchenne muscular dystrophy (DMD) in patients aged 2 years and older, as well as for other inflammatory disorders such as asthma, rheumatoid arthritis, severe allergies, and certain rheumatic conditions when glucocorticoid therapy is warranted.

It works by suppressing immune overactivity and reducing inflammation, helping relieve symptoms and prevent tissue damage. In DMD, it helps slow muscle weakness progression. Because it is a steroid medicine, it must be used carefully, following the exact dose and duration recommended by a healthcare provider.

Composition:

Each uncoated tablet contains- Deflazacort: 6 mg and Excipients q.s.

Uses & Benefits of Jitodef 6 Tablet:

Jitodef 6 Tablet is highly effective for several conditions -

• Arthritis: Reduces joint pain and swelling associated with rheumatoid arthritis and other rheumatic disorders.
• Duchenne Muscular Dystrophy (DMD): Helps slow the progression of muscle weakness in Duchenne muscular dystrophy (DMD), supporting better mobility and daily function in affected children and young adults.
• Autoimmune Disorders: Offers immunosuppressive action that can help manage certain autoimmune conditions.
• Asthma & Allergies: Provides effective relief from inflammation in conditions like bronchial asthma and severe allergic reactions.

How Jitodef 6 Tablet Works:

Jitodef 6 Tablet contains Deflazacort, is a corticosteroid that reduces inflammation and controls an overactive immune system. It is converted in the body into an active form that binds to glucocorticoid receptors, blocking chemicals that cause swelling and tissue damage. It also prevents the immune system from attacking healthy tissues. In Duchenne muscular dystrophy, it helps protect muscles and slow disease progression when taken regularly as prescribed.

Dosage of Jitodef 6 Tablet:

• Usage Direction

Take Jitodef 6 Tablet strictly according to your doctor’s instructions, following the prescribed dose and timing. Jitodef 6 Tablet should be swallowed whole without crushing, chewing, or breaking it, preferably at the same time each day. Do not stop or alter the dose of Jitodef 6 Tablet without consulting your doctor, as this may prevent you from achieving the desired outcome. If you are unsure about the administration procedures of Jitodef 6, consult with your doctor or pharmacist.

• Missed Dose

If you miss a dose of Jitodef 6 Tablet, take it as soon as you remember on the same day. But, if it is almost time for your next scheduled dose, skip the one you missed and continue following your regular dosing schedule. Do not attempt to take two doses if you have forgotten one.

• Overdose

If you accidentally take Jitodef 6 Tablet more than your prescribed dose, seek immediate medical advice, as this may lead to serious side effects.

Contraindications of Jitodef 6 Tablet:

Do not take Jitodef 6 Tablet if you are hypersensitive or allergic to deflazacort or any of the components of this medicine. Some of the symptoms of allergic reactions are difficulties in breathing and swallowing, rashes, and swelling of the face, lips, tongue, or throat.

Avoid using this medicine if you have a systemic (whole-body) fungal infection or if you have recently received a live vaccine immunisation, as it may weaken your immune response.

Precautions & Warnings of Jitodef 6 Tablet:

Before starting Jitodef 6 Tablet (Deflazacort), inform your doctor if you have conditions such as epilepsy, diabetes, high blood pressure, or any kidney, liver, or heart problems. Also mention osteoporosis, an underactive thyroid, tuberculosis, oesophagitis, ulcerative colitis, diverticulitis, or stomach/peptic ulcers.

Use with caution alongside antibiotics like Ciprofloxacin, as it may increase the risk of tendon inflammation. Some people may also experience irregular periods. Your doctor may adjust treatment or monitor you more closely if needed.

Side Effects Of Jitodef 6 Tablet:

Jitodef 6 Tablet may cause some side effects, but they may not occur in all individuals and can vary from person to person. However, if these symptoms continue, it is necessary to consult your doctor. Using corticosteroids for an extended period can result in Cushing’s syndrome (high cortisol), allergic reactions, increased appetite, weight gain, stomach discomfort, improper heart, liver, and kidney functions, mood disturbances, muscle weakness, myopathy, immune suppression, and others.

There are side effects that can be more severe and require quick medical attention, like altered hormone functions, hyperglycemia, psychotic disorders, joint and bone pain, melena (blood in stool), or other digestive issues, Kaposi’s Sarcoma, serious skin rashes, chronic fever, or infections.

Safety Related Concerns of Jitodef 6 Tablet:

• Pregnancy

If you are pregnant or planning to become pregnant, talk to your doctor to determine if Jitodef 6 Tablet is safe for you, as studies on animal reproduction have shown that when corticosteroids are administered, abnormalities of foetal development including cleft palate, intra-uterine growth retardation and effects on brain growth and development.

• Breastfeeding

Deflazacort can pass into breast milk in small quantities. If you are breastfeeding, inform your doctor before taking Jitodef 6 Tablet.

• Alcohol

Avoid drinking alcohol while taking Jitodef 6 Tablet.

• Using Machinery & Driving

Jitodef 6 Tablet may cause dizziness or a spinning sensation (vertigo), which can reduce alertness and impact on your ability to drive or operate machinery safely. Avoid such activities until you know how the medicine affects you, and inform your doctor if these symptoms occur.

• Food Interactions

During the use of Jitodef 6 Tablet, it is recommended not consume grapefruit or grapefruit juice, as this could raise the levels of deflazacort in your bloodstream, thereby increasing the risk of side effects.

• Drug Interactions

Jitodef 6 Tablet can interact with some medicines, so always inform your doctor about everything you take, including prescription drugs, over-the-counter medications, vitamins, minerals, and herbal supplements, to avoid potential interactions. Drugs affecting liver enzymes (CYP3A4) may alter its action; inhibitors like Ketoconazole and Clarithromycin can increase its effects, while inducers like rifampicin, carbamazepine, and Phenytoin may reduce them.

It may also interact with Warfarin, insulin, diuretics, NSAIDs, muscle relaxants, oral contraceptives, and HIV medicines like ritonavir. Corticosteroids can reduce the effect of antidiabetic and antihypertensive drugs and increase potassium loss. Keep a 2-hour gap with antacids, and avoid live vaccines. Regular monitoring and dose adjustment may be needed.

Storage of Jitodef 6 Tablet:

Store at a temperature not exceeding 30°C. Protect from light and moisture.

Keep out of the reach of children.

Avoid using this medicine after the expiry date, printed on the packaging. Dispose of expired or unused medication properly; do not throw it away casually.

Additional Information:

• Jitodef 6 Tablet is a potent corticosteroid that should only be used under medical supervision.
• Regular follow-ups are essential to monitor its effectiveness and detect any side effects early.
• Patients should not share this medication with others, even if symptoms appear similar.
• Lifestyle modifications, including a healthy diet and regular exercise, can enhance treatment outcomes.
• Always follow your doctor’s instructions carefully for safe and effective use.
• If used for more than 3 weeks, carry your steroid card at all times and show it during medical emergencies.

Frequently Asked Questions (FAQs):

Q. Is Jitodef 6 Tablet a steroid medicine?

A: Yes, Jitodef 6 Tablet is a corticosteroid medicine contains deflazacort. It is indicated for inflammatory disorders, autoimmune diseases, severe allergic reactions, nephrotic syndrome, and Duchenne muscular dystrophy (DMD). It works by reducing inflammation and calming an overactive immune response.

Q. Can I stop taking Jitodef 6 Tablet on my own?

A: No, you should never stop taking Jitodef 6 Tablet abruptly without your doctor's guidance. Sudden discontinuation after prolonged use can trigger adrenal insufficiency, causing symptoms like persistent fatigue, dizziness, nausea, and low blood pressure. Your doctor will taper the dose gradually and safely.

Q. Does taking Jitodef 6 Tablet increase by blood sugar level?

A: Yes, taking Jitodef 6 Tablet can lead to an increase in your blood sugar levels (diabetes), which is one of its potential side effects. Your doctor may need to monitor your blood glucose levels periodically to ensure the medication is working effectively and to avoid any possible side effects.

Q. Does Jitodef 6 Tablet cause weight gain?

A: Some patients may experience mild weight gain and an increase in appetite while on Jitodef 6 Tablet. Compared to other commonly used corticosteroids like prednisolone, Deflazacort is generally associated with less weight gain and fluid retention, which is why it is often preferred for conditions requiring long-term steroid therapy.

Q. Is Jitodef 6 Tablet safe to take during pregnancy?

A: Jitodef 6 Tablet should only be used during pregnancy when the doctor has determined that the clinical benefit clearly outweighs the potential risk to the baby. Deflazacort crosses the placenta and has been linked to certain developmental risks including orofacial clefts and low birth weight. Always discuss this with your treating physician before use.

Q. How long should Jitodef 6 Tablet be taken safely?

A: The duration of your treatment is based on its nature and any other health conditions or medications you are currently using. Your doctor will determine the shortest effective treatment plan and make modifications if necessary.

Reference:

1. Package Leaflet: Information For The User. Calcort 6mg Tablets (deflazacort). Last Revised: 21st June 2017. Accessed on: 9th May 2026. Click Here

2. ELDOCORTTM – 6 (DEFLAZACORT TABLETS 6 mg). Last Revised: January 2019. Accessed on: 9th May 2026. Click Here

3. HIGHLIGHTS OF PRESCRIBING INFORMATION. EMFLAZA (deflazacort). Last Revised: February, 2019. Accessed on: 9th May 2026. Click Here

4. New Drugs Approved by CDSCO (Central Drugs Standard Control Organisation). Accessed on: 9th May 2026. Click Here