Jitodapa SI 10/100 Tablet (10 Tab)

Jitodapa SI 10/100 Tablet Overview:

Jitodapa SI 10/100 Tablet is an oral anti-diabetic medication used to manage blood glucose levels in adults with Type 2 Diabetes Mellitus.

It combines two active ingredients, Dapagliflozin and Sitagliptin. This dual-action approach helps the body lower glucose through multiple pathways, particularly when dietary changes, physical activity, and single-drug therapy are insufficient.

Proper management is crucial because Type 2 diabetes can lead to serious complications, including cardiovascular diseases like heart attack and stroke, as well as kidney damage, nerve damage, vision problems, and slow wound healing.

Jitodapa SI 10/100 Tablet contributes to lowering these risks by eliminating extra glucose via urine and supporting insulin activity. For optimal results, this medication should be used in combination with a healthy diet and regular exercise, as advised by your doctor.

Composition:

Each film coated tablet contains- Sitagliptin Phosphate Monohydrate eq. to Sitagliptin: 100 mg and Dapagliflozin Propanediol eq. to Dapagliflozin: 10 mg.

Colours: Ferric Oxide (Red).

Uses & Benefits of Jitodapa SI 10/100 Tablet:

Jitodapa SI 10/100 Tablet is prescribed for the treatment of Type 2 diabetes mellitus or non-insulin-dependent diabetes mellitus (NIDDM).

How Does Jitodapa SI 10/100 Tablet Work:

Jitodapa SI 10/100 Tablet comprises Dapagliflozin, a potent (SGLT2) inhibitor, and Sitagliptin (DPP-4) inhibitor, which work together through two distinct mechanisms to manage blood sugar levels.

Dapagliflozin works in the kidneys by blocking the reabsorption of glucose back into the bloodstream and removing excess glucose from the body through urine, thereby lowering blood sugar levels.

Whereas Sitagliptin works by increasing the levels of "incretin" hormones. These hormones stimulate the pancreas to release more insulin when blood sugar is high, especially after a meal, and signal the liver to stop producing excess sugar.

Dosage of Jitodapa SI 10/100 Tablet:

• Usage Direction

Jitodapa SI 10/100 Tablet should be taken strictly as per the doctor’s advice, following the prescribed dose and timing. Jitodapa SI 10/100 Tablet is to be swallowed whole, not to be chewed or crushed. Take Jitodapa SI 10/100 Tablet preferably at the same time each day. Do not stop or alter the dose of Jitodapa SI without consulting your doctor, as this may prevent you from achieving the desired outcome. If you are unsure about the administration procedures of this medication, consult with your doctor or pharmacist.

• Missed Dose

If you forget to take a dose of Jitodapa SI 10/100 Tablet and your next dose is scheduled for more than 12 hours later, take it as soon as you recall. However, if your next dose is due within 12 hours, skip the missed dose and stick to your usual dosing routine. Avoid taking two doses if you have missed one, as it might increase the risk of side effects. If you often forget to take your medication, consult with your doctor to re-evaluate your dosing schedule. Frequently missing doses could lead to undesired outcomes.

You can set reminders on your smartphone, keep drug organizer boxes, or use other audio-visual technologies to prevent missing a dose.

• Overdose

If you accidentally take Jitodapa SI 10/100 Tablet more than your prescribed dose, seek immediate medical advice or contact a poison control center.Symptoms may include severe hypoglycemia (low blood sugar) or dehydration.

Contraindications of Jitodapa SI 10/100 Tablet:

Do not take Jitodapa SI 10/100 Tablet if you are allergic to Dapagliflozin, Sitagliptin, or any of its ingredients. Symptoms of an allergic reaction may include skin rash, itching, hives, breathing difficulty, or swelling of the face, lips, tongue, or throat.

This medicine is not to be used for the treatment of type 1 diabetes mellitus, diabetic ketoacidosis, severe liver disease, or severe kidney disease, including patients with end-stage renal disease or those undergoing dialysis. Jitodapa SI 10/100 Tablet should also not be used in children and adolescents below 18 years of age.

Precautions & Warnings of Jitodapa SI 10/100 Tablet:

Before taking Jitodapa SI 10/100 Tablet, inform your doctor if you have a history of pancreatitis, liver disease, kidney problems, heart failure, low blood pressure, allergic reactions, or frequent urinary or genital infections.

This medication must be used with caution in patients at risk of hypoglycemia—particularly those using insulin or other glucose-lowering drugs—and it is not intended for the treatment of Type 1 diabetes.

Stay alert for signs of Diabetic Ketoacidosis (DKA), a serious condition that may occur even if blood sugar levels are not significantly elevated. If you experience nausea, vomiting, abdominal pain, excessive thirst, breathing difficulty, confusion, or unusual tiredness, seek medical attention immediately. Furthermore, if you suffer from a fever, severe infection, diarrhea, or a decrease in food and fluid intake, consult your physician promptly, as these conditions significantly increase the risk of dehydration and kidney stress while taking this medication.

Side Effects of Jitodapa SI 10/100 Tablet:

Jitodapa SI 10/100 Tablet may cause side effects, most of which are mild and temporary as the body adjusts to the medication. The most common side effect of Jitodapa SI 10/100 Tablet is a urinary tract infection (UTI), which may cause fever, chills, or a burning sensation during urination. Other common side effects include constipation, abdominal pain, back pain, dizziness, skin rash, nasopharyngitis (swelling in the nasal or throat area), frequent urination, weight loss, and fungal yeast infections in the genital area.

Some rare and serious side effects may also occur, which need immediate medical attention. These include severe allergic reactions, pancreatitis (severe stomach pain), and dehydration. Be particularly mindful of hypoglycemia (low blood sugar), especially if this medication is used alongside insulin or sulfonylureas. Rare but critical conditions such as Fournier’s gangrene (infection of the genital area) and diabetic ketoacidosis, marked by excessive thirst, dry mouth, and rapid weight loss. If you notice any persistent or unusual symptoms while taking Jitodapa SI 10/100 Tablet, contact your doctor immediately.                                                                                                          

Safety Related Concerns of Jitodapa SI 10/100 Tablet:

• Pregnancy

Jitodapa SI 10/100 Tablet is generally not recommended during pregnancy, as there is limited data on the safety of this medicine during pregnancy. If you are pregnant or planning to become pregnant while taking Jitodapa SI, consult your healthcare provider immediately. Your healthcare provider may switch to safer alternatives to maintain normal blood sugar levels.

Careful and regular blood glucose monitoring during pregnancy is essential to reduce the risk of complications and support healthy fetal development. Always follow your doctor’s advice and do not start or stop any diabetes medication without medical guidance.

• Breastfeeding

It is better to avoid the use of the Jitodapa SI 10/100 Tablet while breastfeeding, since it is unknown whether the active ingredients of this medicine could pass into the breast milk and affect the breastfed child. Therefore, consulting with your doctor before taking Jitodapa SI 10/100 Tablet is crucial.

• Alcohol

Avoid alcohol consumption while taking Jitodapa SI 10/100 Tablet, as it may increase the risk of lactic acidosis and can cause unpredictable fluctuation in blood sugar levels.

• Food Interactions

No specific food interactions have been documented for Jitodapa SI 10/100 Tablet, as it can be taken with or without a meal. However, maintaining a consistent, diabetic-friendly diet is essential for effective blood glucose management. It is recommended to avoid sugary items and limit highly processed carbohydrates, as these are the primary causes of blood sugar spikes. While there are no specific food restrictions related to the medicine itself, a balanced diet enhances the overall success of the treatment.

• Drug Interactions

Jitodapa SI 10/100 Tablet may interact with certain medicines. Inform your doctor if you are taking diuretics (water pills), as they can increase the risk of dehydration. Using it with insulin or sulfonylureas may raise the chance of low blood sugar, requiring dose adjustments.

Caution is also advised if you are taking anti-hypertensive or heart medications, such as ACE inhibitors. Additionally, certain medicines like rifampicin, carbamazepine, phenobarbital, and phenytoin may reduce the effectiveness of this tablet by decreasing the concentration of its active ingredients in the blood. The tablet might also interact with lithium by reducing its levels, potentially making it less effective.

Always inform your healthcare provider and pharmacist about all medications you are taking, including prescription drugs, over-the-counter medications, vitamins, minerals, and herbal supplements, to avoid potential interactions.

• Using Machinery & Driving

Using Jitodapa SI 10/100 Tablet may affect your ability to drive or operate machinery, especially when taken with other anti-diabetic medicines such as insulin or sulphonylureas. These combinations can cause low blood sugar (hypoglycemia), which may lead to symptoms like blurred vision, dizziness, shaking, or sweating. If you feel unwell or dizzy, then avoid driving or such activities.

Always carry a quick source of glucose, such as fruit juice or candies, in case of an emergency.

Storage of Jitodapa SI 10/100 Tablet:

Store protected from light and moisture, at a temperature not exceeding 30°C. Keep out of reach of children. Avoid using it after the expiry date, printed on the packaging. Dispose of expired or unused medication properly; do not throw it away casually.

Additional Notes:

• Maintain a healthy lifestyle, including a balanced diet, regular physical activity, weight management, and stress reduction.
• Maintain all scheduled appointments for blood tests and check-ups to monitor kidney function, liver function, and other parameters.
• Diabetics should check their feet daily for sores or infections.
• Do not share your medicine with other persons, even if they also have similar symptoms.
• Carry quick sugar sources in case of low blood sugar.

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Frequently Asked Questions (FAQs)-

Q. What is Jitodapa SI 10/100 Tablet used for and how it works?

A: Jitodapa SI 10/100 Tablet is used to treat Type 2 Diabetes Mellitus in adult patients. It helps to decrease glucose production in the liver, reduce sugar reabsorption in the kidneys, and increase insulin production in the pancreas. Through these combined actions, it effectively manages and stabilizes elevated blood sugar levels.

Q. Can Jitodapa SI 10/100 Tablet be used for long-term?

A: Yes, it is typically prescribed for long-term management of type 2 diabetes under medical supervision.

Q. Can I stop taking Jitodapa SI 10/100 Tablet once my blood sugar is normal?

A: No, Jitodapa SI 10/100 Tablet is a preventive medicine to manage elevated blood sugar, and diabetes is a chronic condition. Stopping medication without a doctor's advice can lead to a dangerous spike in blood sugar.

Q. Can Jitodapa SI cause weight loss?

A: Yes, many patients experience modest weight loss while taking Jitodapa SI 10/100 Tablet. This is primarily due to the active ingredient Dapagliflozin, which causes the body to lose calories as excess glucose is excreted through the urine. While Sitagliptin is generally weight-neutral, the combination often leads to a reduction in body weight. However, if you experience sudden or significant weight loss, it is essential to consult your doctor right away to ensure it is not a sign of a more serious condition like dehydration or ketoacidosis.

Q. What should I do if I feel sweaty and shaky?

A: These are signs of low blood sugar (hypoglycemia). Consume a quick source of sugar (like fruit juice or glucose tablets) and consult your doctor.

Q. Who should not take Jitodapa SI 10/100 Tablet?

A: Jitodapa SI 10/100 Tablet should be avoided if you are under 18 years of age, pregnant, or breastfeeding. Do not take this medicine if you have severe kidney disease, are on dialysis, or have type 1 diabetes. It is also not suitable for patients with a history of pancreatitis, liver problems, heart complications, or known allergy to any of its ingredients.

References:

1. Package leaflet: Information for the patient. Zensita-D (50 mg + 5 mg) & (100 mg + 10 mg) film-coated tablets. sitagliptin/dapagliflozin. Last Revised: June 2023. Accessed on: 19th March 2026. Click Here

2. Package leaflet: Information for the patient. Sitagliptin/Dapagliflozin Teva 100 mg/10 mg film-coated tablets. sitagliptin/dapagliflozin. Last Revised: 19 Nov 2025. Accessed on: 19th March 2026. Click Here

3. AUSTRALIAN PRODUCT INFORMATION. SIDAPVIA™ 10/100 (dapagliflozin/sitagliptin) tablets. Accessed on: 19th March 2026. Click Here

4. SIDAPVIA™ 10/100. Consumer Medicine Information (CMI) summary. Last Revised: June 2024. Accessed on: 19th March 2026. Click Here