Jitoclopi 75 Tablet (10 Tab)

Jitoclopi 75 Tablet Overview:

Jitoclopi 75 mg Tablet is an antiplatelet medicine, commonly known as a blood thinner, used to prevent harmful blood clots from forming inside the blood vessels. By improving blood flow, it helps lower the risk of serious cardiovascular conditions such as heart attack and stroke.

It contains Clopidogrel as the active ingredient, which works by reducing the ability of platelets, the blood cells responsible for clotting, to stick together and form clumps in narrowed or damaged arteries. This action helps maintain smooth circulation and protects the heart and blood vessels from clot-related complications.

Jitoclopi 75 Tablet is commonly prescribed for people with peripheral vascular disease, a recent heart attack, irregular heartbeat, or those who have undergone heart procedures such as angioplasty or stent placement.

Composition:

Each film coated tablet contains- Clopidogrel Bisulfate equivalent to Clopidogrel: 75 mg and Excipients q.s.

Colour: Ferric Oxide Red & Titanium Dioxide

Uses & Benefits of Jitoclopi 75 Tablet:

Jitoclopi 75 Tablet is primarily used for the prevention of thromboembolic events (blood clots) in patients with a history of:

• Myocardial Infarction (Heart Attack): Decreases the likelihood of experiencing a recurrent heart attack.
• Ischemic Stroke: Prevents a subsequent stroke caused by a blood clot interrupting blood flow to the brain.
• Peripheral Arterial Disease (PAD): Improves blood circulation and manages complications arising from narrowed blood vessels in the limbs.
• Acute Coronary Syndrome (ACS): Helps manage unstable angina (severe chest pain) or acute heart attacks. It is often used in combination with aspirin after procedures like cardiac stent placement (percutaneous coronary intervention) to keep the stent open and clear.

How Does Jitoclopi 75 Tablet Work:

Jitoclopi 75 Tablet contains Clopidogrel, belongs to a class of medications called antiplatelet medication. It works by preventing platelets, the tiny blood cells involved in clot formation, from sticking together. It blocks specific receptors called P2Y12 receptors on the surface of platelets, which are activated by a substance known as ADP (adenosine diphosphate).

By blocking these receptors, clopidogrel reduces platelet activation and prevents the formation of harmful blood clots inside the blood vessels. This helps maintain proper blood flow and lowers the risk of serious conditions such as heart attack, stroke, and clot-related complications after procedures like angioplasty or stent placement.

This means the medicine is initially inactive and must be metabolized by liver enzymes to become active.

Dosage of Jitoclopi 75 Tablet:

• Usage Direction

Take Jitoclopi 75 Tablet strictly according to your doctor’s instructions, following the prescribed dose and timing. Do not crush, chew, or break the tablet. Jitoclopi 75 Tablet should be swallowed whole with water, preferably at the same time each day. Do not stop or alter the dose of Jitoclopi 75 Tablet without consulting your doctor, as this may prevent you from achieving the desired outcome. If you are unsure about the administration procedures of Jitoclopi 75, consult with your doctor or pharmacist.

• Missed Dose

If you miss a dose of Jitoclopi 75 Tablet, take it as soon as you remember on the same day. But, if it is almost time for your next scheduled dose, skip the one you missed and continue following your regular dosing schedule. Do not attempt to take two doses if you have forgotten one. If you often forget to take your medication, consult with your doctor to re-evaluate your dosing schedule. Frequently missing doses could lead to undesired outcomes.

You can set reminders on your smartphone, keep drug organizer boxes, or use other audio-visual technologies to prevent missing a dose.

• Overdose

An overdose of Jitoclopi 75 can lead to prolonged bleeding time and subsequent bleeding complications (both internal and external). Symptoms of an overdose may include unusual or heavy bleeding, easy bruising, or blood in the urine and stools. If an overdose is suspected, seek emergency medical attention or contact a poison control center immediately.

Contraindications of Jitoclopi 75 Tablet:

Do not take Jitoclopi 75 Tablet if you have known hypersensitivity or allergy to Clopidogrel or any other ingredients of this medicine.

It is also strictly contraindicated for patient currently experiencing active pathological bleeding, such as an active stomach ulcer or bleeding inside the brain. Furthermore, individuals with severe liver impairment must avoid this medication.

Additionally, Jitoclopi 75 is not recommended for children as its safety and effectiveness have not been established for pediatric patients.

Precautions & Warnings of Jitoclopi 75 Tablet:

Before starting Jitoclopi 75 Tablet, it is essential to consult your healthcare provider, particularly if you have a medical history involving recent serious injuries, kidney or liver disease, stomach ulcers, or bleeding in the brain.

You must also inform your surgeon or dentist that you are taking this medication well in advance of planning any surgical or dental procedures, as it may need to be temporarily stopped to prevent excessive bleeding.

While on this medicine, it may take longer than usual for bleeding to stop if you accidentally cut or injure yourself.

Contact your doctor immediately if you experience heavy, uncontrollable bleeding or if you develop symptoms of a rare but serious blood disorder called Thrombotic Thrombocytopenic Purpura (TTP), which can cause fever, extreme fatigue, purple skin spots, or yellowing of the skin and eyes.

Side Effects of Jitoclopi 75 Tablet:

Jitoclopi 75 Tablet may cause side effects, although not everyone will experience them. Bleeding is the most common side effect, and in some cases, it becomes serious or life-threatening. Common, symptoms often include easy bruising, frequent nosebleeds, prolonged bleeding from minor wound sites, diarrhea, abdominal pain, indigestion, or heartburn.

Patients may also occasionally experience uncommon symptoms such as a decreased blood platelet count (thrombocytopenia), headaches, dizziness, nausea, vomiting, constipation, skin itching, or mild rashes.

However, some serious side effects can occur that require immediate medical attention. You should contact an emergency healthcare provider right away if you notice signs of internal gastrointestinal bleeding (such as coughing up blood or dark, tarry stools), symptoms of an intracranial hemorrhage (like a sudden, severe headache or confusion), or severe allergic reactions (angioedema) causing swelling of the face, lips, or throat.

Safety Related Concerns of Jitoclopi 75 Tablet

• Pregnancy

The use of Jitoclopi 75 Tablet is generally not recommended during pregnancy because there are no adequate and well-controlled studies evaluating its safety in pregnant women. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, and it must be strictly prescribed and monitored by a doctor.

• Breastfeeding

It is better to avoid the use of the Jitoclopi 75 Tablet while breastfeeding, since it is unknown whether Clopidogrel is excreted in human breast milk. Therefore, consulting with your doctor before taking Jitoclopi 75 Tablet is crucial.

• Alcohol

It is advised to avoid or significantly limit alcohol consumption while taking Jitoclopi 75 Tablet. Heavy alcohol use increases the risk of stomach ulcers and gastrointestinal bleeding while taking blood thinners.

• Food Interactions

Jitoclopi 75 Tablet can be taken with or without food, and there is no known food-drug interaction. You should be cautious with spices like ginger, garlic, or ginkgo, as these can increase your risk of bleeding or reduce the effectiveness of medication. For the best results, maintain a steady, balanced diet and always check with your healthcare provider before starting any new herbal products or concentrated supplements.

• Drug Interactions

Jitoclopi 75 Tablet can interact with several other medications, which may either reduce its ability to prevent clots or significantly increase your risk of bleeding. It is vital to inform your doctor if you are taking nonsteroidal anti-inflammatory drugs (NSAIDs) commonly used for pain relief (such as ibuprofen or diclofenac), other oral anticoagulants (such as warfarin), injectable blood thinners (such as heparin), or selective serotonin reuptake inhibitors (SSRIs) used for depression, as all of these can drastically increase your susceptibility to serious bleeding.

Conversely, certain medications can reduce the effectiveness of clopidogrel. This includes proton pump inhibitors (PPIs) (such as omeprazole and esomeprazole), antifungals (such as fluconazole and voriconazole), anti-HIV drugs (such as efavirenz), anticonvulsants (such as carbamazepine), antidepressants (such as moclobemide), diabetes medications (such as repaglinide), and chemotherapy agents (such as paclitaxel).

Always inform your healthcare provider and pharmacist about all medications you are taking, including prescription drugs, over-the-counter medications, vitamins, minerals, and herbal supplements, to avoid potential interactions.

• Using Machinery & Driving

Jitoclopi 75 Tablet generally does not affect your ability to drive or operate machinery. However, use caution when driving or operating heavy machinery until you know how Jitoclopi 75 Tablet affects you.

However, if you experience dizziness or headaches as a side effect, avoid these activities until you feel stable.

Storage of Jitoclopi 75 Tablet:

Store protected from moisture, at a temperature not exceeding 30°C. Keep the medicine out of reach of children.

Avoid using it after the expiry date, printed on the packaging. Dispose of expired or unused medication properly; do not throw it away casually.

Additional Information:

• Focus on a diet rich in whole grains, lean proteins, vegetables, and fruits. Reduce your intake of saturated fats, trans fats, and sodium to manage cholesterol and blood pressure.
• Engage in moderate aerobic exercise (like brisk walking) for at least 150 minutes per week, as approved by your cardiologist.
• Maintaining a healthy body mass index (BMI) reduces stress on your cardiovascular system.
• Smoking significantly accelerates the hardening of arteries and increases blood clotting risks. Quitting smoking is one of the most impactful steps to maximize the benefits of this therapy.
• Use caution when handling knives, razors, or nail clippers. Consider using an electric shaver and a soft-bristled toothbrush to prevent bleeding gums.
• Do not suddenly stop your medication unless your doctor specifically tells you to.
• Do not share your medicine with someone else having the same symptoms as you.

Frequently Asked Questions (FAQs):

Q. Is Jitoclopi 75 Tablet a blood thinner?

A. Yes, Jitoclopi 75 Tablet belongs to a class of medicines called antiplatelet medications, which are commonly referred to as "blood thinners." It does not literally change the thickness or viscosity of your blood; instead, it works by making your platelets less sticky, preventing them from clumping together to form dangerous, obstructive blood clots.

Q. Can I stop taking Jitoclopi 75 if I feel better?

A. No, you should never stop taking this medication on your own, even if you feel completely healthy. Feeling better simply means the medicine is working effectively. Stopping Jitoclopi 75 without advice, especially if you have recently had a heart attack, a stroke, or a cardiac stent placement, dramatically increases your risk of a recurrent, potentially fatal cardiovascular event.

Q. What should I do if I notice unusual bruising or a prolonged nosebleed?

A. You should contact your healthcare provider promptly. While minor bruising or occasional small nosebleeds can be a common side effect of antiplatelet therapy, large unexplained bruises, bleeding that happens without an injury, or a nosebleed that does not stop within few minutes require immediate medical evaluation. Your doctor may need to check your bleeding parameters to ensure you are safely managing the medication.

Q. Can I take pain relievers like ibuprofen with Jitoclopi 75 Tablet?

A. Generally, no. Pain relievers classified as Nonsteroidal Anti-inflammatory Drugs (NSAIDs) such as ibuprofen, naproxen, and diclofenac can irritate your stomach lining and interfere with blood clotting. Combining them with Jitoclopi 75 Tablet significantly multiplies your risk of developing severe internal or gastrointestinal bleeding. Your doctor may suggest you some safer alternatives for mild pain or fever relief.

Q. Do I have to stop taking Jitoclopi 75 Tablet before surgery?

A. Yes, you will likely need to temporarily stop taking this medication before any scheduled surgery or major dental work because it increases the risk of excessive bleeding during and after the procedure. However, you should never stop taking this medicine on your own; always discuss your upcoming procedure with both your surgeon and your cardiologist so they can provide a safe, coordinated plan for your treatment.

Reference:

1. Package leaflet: Information for the patient. Clopidogrel 75 mg Film-coated Tablets (clopidogrel). Last Revised: October 2017. Accessed on: 20th May 2026. Click Here

2. Clopidogrel Krka 75 mg film-coated tablets. Summary of Product Characteristics. Accessed on: 20th May 2026. Click Here

3. PLAVIX. Prescribing Information. Last Revised: September 2016. Accessed on: 20th May 2026. Click Here