Jitoamlo ML 5/50 Tablet (10 Tab)

Jitoamlo ML 5/50 Tablet Overview:

Jitoamlo ML 5/50 Tablet is an anti-hypertensive medication primarily used to treat hypertension (high blood pressure) and manage angina pectoris (chronic chest pain).

High blood pressure (hypertension) puts continuous pressure on the walls of the arteries. Angina happens when the heart does not get enough oxygen-rich blood because the coronary arteries are narrowed. If not controlled, both conditions can increase the risk of serious problems such as a heart attack or stroke.

Jitoamlo ML 5/50 Tablet is composed of two active salts: Amlodipine (a calcium channel blocker) and Metoprolol Succinate (a beta-1 adrenergic receptor blocker). Amlodipine relaxes blood vessels and improves blood flow, while Metoprolol reduces heart rate and cardiac workload.

Together, they act synergistically to manage elevated blood pressure and reduce the risk of serious cardiovascular events in high-risk patients.

Composition:

Each film coated tablet contains- Metoprolol Succinate (As prolonged release form): 50 mg, Amlodipine Besylate eq. to Amlodipine: 5 mg and Excipients q.s,

Colours: Titanium Dioxide.

Uses & Benefits of Jitoamlo ML 5/50 Tablet:

The therapeutic uses and benefits of Jitoamlo ML 5/50 Tablet include:

• Treatment of Hypertension: Effectively lowers elevated blood pressure when single-drug therapy is insufficient and reduces chronic strain on vital organs.
• Management of Angina Pectoris: Helps prevent recurrent chest pain episodes by improving myocardial oxygen delivery, decreasing cardiac oxygen demand, and workload.
• Prevention of Major Cardiovascular Events: Significantly decreases the long-term risk of life-threatening cardiovascular complications, including myocardial infarction (heart attack), stroke, and heart failure, particularly in high-risk patients.

How Does Jitoamlo ML 5/50 Tablet Work:

Jitoamlo ML 5/50 Tablet combines two active ingredients, Amlodipine and Metoprolol, which lower blood pressure and protect your heart through two distinct mechanisms.

Amlodipine is a long-acting dihydropyridine calcium channel blocker, which inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. This induces peripheral vasodilation, reducing total peripheral resistance and systemic blood pressure.

At the same time, Metoprolol Succinate is a cardioselective beta-1 adrenergic receptor blocker that selectively blocks beta-1 receptors in the heart, slowing the heart rate, decreasing cardiac output, and reducing strain during heart contraction, helping the heart to pump blood more efficiently.

Together, they take the heavy workload off your heart, ensure it gets plenty of oxygen-rich blood to stop chest pain, and keep your blood pressure under control.

Dosage of Jitoamlo ML 5/50 Tablet:

• Usage Directions

Take Jitoamlo ML 5/50 Tablet strictly according to your doctor’s instructions, following the prescribed dose and timing. Jitoamlo ML 5/50 Tablet should be swallowed whole with water and not chewed, cut, or crushed, preferably at the same time each day. Do not stop or alter the dose of Jitoamlo ML 5/50 Tablet without consulting your doctor, as this may prevent you from achieving the desired outcome. If you aren't sure how to take Jitoamlo ML 5/50, check with your healthcare provider or pharmacist for instructions.

• Missed Dose

If you miss a dose of Jitoamlo ML 5/50 Tablet, take it as soon as you remember on the same day. If it's almost time for your next dose, skip the missed dose and proceed with your usual routine. Do not take a double dose if you have forgotten one.

To avoid missing doses, set reminders on your smartphone, keep drug organizer boxes, or use other audio-visual technologies.

• Overdose

If you accidentally take Jitoamlo ML 5/50 Tablet more than your prescribed dose, seek immediate medical advice or contact a poison control center immediately. An overdose can cause severe hypotension, bradycardia (dangerously slow pulse), reflex tachycardia, nausea, vomiting, or cardiogenic shock.

Contraindications of Jitoamlo ML 5/50 Tablet:

Do not take Jitoamlo ML 5/50 Tablet if you have a known allergy or hypersensitivity to Amlodipine, Metoprolol, beta-blockers, dihydropyridine calcium channel blockers, or any other inactive component present in this medication. It must be avoided in patients with severe hypotension, severe bradycardia (heart rate < 45–50 bpm), cardiogenic shock, decompensated heart failure, or severe peripheral arterial circulatory disorders.

Furthermore, the medication should be avoided in individuals diagnosed with second- or third-degree atrioventricular (AV) block or sick sinus syndrome in the absence of a functioning pacemaker—as well as those with advanced peripheral arterial circulatory disorders, active bronchospasm, a history of bronchial asthma, severe chronic obstructive pulmonary disease (COPD), or diabetes prone to recurrent hypoglycemic episodes.

Precautions & Warnings of Jitoamlo ML 5/50 Tablet:

Before starting Jitoamlo ML 5/50 Tablet, inform your healthcare provider about your complete medical history. Close monitoring and dose adjustments are essential for patients with liver or kidney impairment, as well as elderly patients.

Patients with heart failure require vigilant observation to avoid precipitating acute decompensation, marked hypotension, or arrhythmias.

Additionally, diabetic individuals must exercise caution because the Metoprolol component can mask the early warning signs of acute hypoglycemia, such as tachycardia, palpitations, and tremors.

Never stop taking this medication abruptly; sudden withdrawal of beta-blockers can lead to rebound hypertension, angina exacerbation, or myocardial infarction. Any reduction or cessation of this medication must be carried out through a gradual, physician-supervised tapering schedule.

Side Effects of Jitoamlo ML 5/50 Tablet:

Jitoamlo ML 5/50 Tablet can cause side effects, although not everyone will experience them. Common symptoms include low blood pressure, tiredness, swollen ankles or feet, dizziness, bradycardia, headache, flushing, nausea, stomach pain, visual disturbance, and muscle cramps.

However, seek immediate medical attention if you experience any serious side effects, such as abnormal heart beat, heart attack, breathing difficulty due to swollen tongue and throat, swelling of face, lips, or eyelids, chest pain, sudden wheezing, pancreatitis, and severe allergic reactions (skin rash, hives, reddening of the skin over your whole body, severe itching, blistering, peeling and swelling of the skin).

Safety Related Concerns of Jitoamlo ML 5/50 Tablet:

• Pregnancy

Jitoamlo ML 5/50 Tablet is not recommended during pregnancy, as limited data exist regarding the safety of this medication in pregnant women. If you are pregnant, suspect you might be pregnant, or are planning to conceive, consult your physician to weigh the clinical benefits against any potential risks to the developing baby.

• Breastfeeding

It is best to avoid using Jitoamlo ML 5/50 Tablet while breastfeeding, since one of its active ingredients Metoprolol passes into breast milk in small quantities and potentially affect the nursing infant. Therefore, consult with your doctor before taking the medicine.

• Alcohol

Avoid consuming alcohol while taking Jitoamlo ML 5/50 Tablet, as it may enhance blood-pressure-lowering effects, leading to severe dizziness, lightheadedness, or fainting.

• Food Interactions

Take Jitoamlo ML 5/50 Tablet with or without food, as advised by the physician. However, avoid consuming grapefruit or drinking grapefruit juice, as it can inhibit drug metabolism and substantially increase Amlodipine concentrations in the bloodstream, elevating the risk of severe hypotension (dangerously low blood pressure) and related side effects.

• Drug Interactions

Jitoamlo ML 5/50 Tablet may interact with other medicines, either by compromising their effectiveness or increasing the risk of toxicity. Concurrent administration with other antihypertensive agents, monoamine oxidase inhibitors (MAOIs), or class I/III antiarrhythmics (such as quinidine, disopyramide, amiodarone, diltiazem, and verapamil) can induce severe bradycardia, conduction disturbances, or excessive hypotension.

Co-administration with strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin) or CYP2D6 inhibitors (e.g., fluoxetine, paroxetine) significantly elevates systemic drug exposure, raising the likelihood of toxicity.

Additionally, nonsteroidal anti-inflammatory drugs (NSAIDs) and systemic corticosteroids may attenuate the blood-pressure-lowering effects of this medication. Other clinical interactions occur with barbiturates, cimetidine, phenothiazines, general anesthetics, and diphenhydramine.

Therefore, always provide your doctor with a complete list of all prescription medications, over-the-counter products, and supplements before starting treatment.

• Using Machinery & Driving

Jitoamlo ML 5/50 Tablet may cause dizziness, drowsiness, or visual disturbances due to lowered blood pressure. Patients should avoid driving or operating machinery until they are sure the medication does not affect their alertness.

Storage of Jitoamlo ML 5/50 Tablet:

Store in a cool, dry & dark place. Keep the medicine out of reach of children.

Discard and do not take this medication after the expiration date printed on the package. It is important to dispose of expired or unused medications properly; do not throw them away casually.

Helpful Tips:

• Adopt the DASH (Dietary Approaches to Stop Hypertension) diet—reduce sodium intake (< 2,300 mg/day), limit saturated fats, and increase potassium-rich fruits and vegetables.
• Engage in at least 150 minutes of moderate aerobic exercise (e.g., brisk walking, cycling) per week to help naturally lower resting arterial pressure.
• Incorporate yoga, deep-breathing exercises, or meditation to minimize adrenergic stress responses.
• Keep a daily home blood pressure and pulse log to help your healthcare provider assess the treatment's ongoing efficacy.
• Do not stop taking your medication suddenly unless your doctor specifically instructs you.
• Never share your medicine with others, even if they have similar symptoms, because this is a prescription drug tailored specifically for you.

Related Blood Pressure Monitoring Device:

To help you stay healthy, explore our range of easy-to-use Blood Pressure Monitors, which are perfect for home use. Check Out

Frequently Asked Questions (FAQs):

Q: What is Jitoamlo ML 5/50 Tablet indicated for?

A: Jitoamlo ML 5/50 Tablet is primarily indicated for the management of hypertension (high blood pressure) and angina pectoris (chronic chest pain). By effectively lowering blood pressure and improving blood flow to the heart, it also helps reduce the long-term risk of major cardiovascular events such as heart attacks and strokes.

Q: Can I stop taking Jitoamlo ML 5/50 once my blood pressure normalizes?

A: No. Normal blood pressure means the medicine is working effectively. Stopping it on your own can trigger a sudden, dangerous spike in blood pressure (rebound hypertension) and increase the risk of chest pain or a heart attack. Never stop or change your dose without consulting your doctor.

Q: Why are my ankles swelling after starting this medicine?

A: Ankle and foot swelling (peripheral edema) is a common side effect caused by Amlodipine, which widens blood vessels and can cause mild fluid accumulation in the lower limbs. Elevating your legs while sitting or resting can often help reduce the swelling. If the swelling becomes uncomfortable, progressively worsens, or is accompanied by shortness of breath, contact your doctor for advice or dosage adjustment.

Q: Is it safe for long-term treatment?

A: Yes, Jitoamlo ML 5/50 Tablet is generally safe and intended for long-term use, as hypertension and chronic stable angina typically require continuous, long-term management to prevent complications like heart attacks and strokes. However, it should be taken under regular medical supervision, with routine monitoring of your blood pressure, heart rate, kidney function, and liver health to ensure it remains safe and effective for you.

Q: Does Jitoamlo ML 5/50 affect blood sugar levels in diabetic patients?

A: While it does not directly spike blood sugar, the Metoprolol component can mask early warning signs of low blood sugar (hypoglycemia), especially rapid heartbeat (tachycardia) and hand tremors. Other signs like sweating or dizziness may still be present. If you have diabetes, check your blood glucose levels more frequently.

Q: Why do I feel dizzy when standing up quickly?

A: This is a mild drop in blood pressure known as orthostatic hypotension, which is common when starting anti-hypertensive therapy. To manage it, transition slowly from lying down or sitting to standing. If severe lightheadedness persists, inform your doctor.

Q: Can I take painkillers like Ibuprofen or Paracetamol with Jitoamlo ML 5/50?

A: Paracetamol is generally safe to take for mild pain or fever. However, you should avoid nonsteroidal anti-inflammatory drugs (NSAIDs) such as Ibuprofen, Naproxen, or Diclofenac without your doctor’s approval. Regular use of NSAIDs can counteract the blood-pressure-lowering effect of Jitoamlo ML 5/50 and increase the strain on your kidneys. Always inform your doctor about any over-the-counter pain relievers or supplements you are taking.

References:

1. METOCARD AM. Metoprolol Succinate Prolonged release and Amlodipine Tablets. Last Revised: January 2020. Accessed on: 4th September 2026. Click Here

2. METOLAR AM Tablet. Metoprolol + Amlodipine. Prescribing information. Last Revised: October 2013. Accessed on: 4th September 2026. Click Here