Jitoamlo AT 5/50 Tablet (10 Tab)

Jitoamlo AT 5/50 Tablet Overview:

Jitoamlo AT 5/50 Tablet is an antihypertensive medicine, commonly prescribed for the treatment of high blood pressure (also known as hypertension), and chest pain related to angina.

This dual-action medicine combines two active ingredients, Amlodipine and Atenolol, that work together to control blood pressure more effectively when a single medicine is not enough to control blood pressure adequately.

By addressing both blood vessel relaxation and heart workload, Jitoamlo AT 5/50 Tablet helps reduce the risk of serious complications such as heart attack, stroke, and kidney damage associated with uncontrolled hypertension.

Composition:

Each uncoated tablet contains- Amlodipine Besilate Equivalent to Amlodipine: 5 mg, Atenolol: 50 mg and Excipients q.s.

Uses & Benefits of Jitoamlo AT 5/50 Tablet:

Primary uses of Jitoamlo AT 5/50 Tablet include:

• Effectively controls high blood pressure through dual mechanisms of action
• Helps reduce the risk of cardiovascular complications such as heart attack and stroke
• Supports long-term heart health in stable angina by improving blood flow and symptom control

How Jitoamlo AT 5/50 Tablet Works:

Jitoamlo AT 5/50 Tablet works through the synergistic actions of its two components. Amlodipine belongs to the class of calcium channel blockers. It works by blocking calcium from entering the blood vessel and heart muscle cells. This causes the blood vessels to relax and widen (vasodilation), reducing resistance to blood flow and lowering blood pressure. It also slightly reduces the force of heart contractions.

Meanwhile, Atenolol is a beta-blocker that works by blocking beta-1 receptors in the heart, which lowers the effect of stress hormones like adrenaline. This slows the heart rate, reduces the strength of heartbeats, and decreases cardiac output. Atenolol also reduces renin release from the kidneys, helping further control blood pressure.

Together, Jitoamlo AT 5/50 Tablet lowers blood pressure and controls heart rate more effectively than a single medicine.

Dosage of Jitoamlo AT 5/50 Tablet:

• Usage Directions

Take Jitoamlo AT 5/50 Tablet strictly according to your doctor’s instructions, following the prescribed dose and timing. The medication can be taken with or without food, though taking it with food may help reduce potential stomach upset. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this may affect its release mechanism and efficacy. It is crucial to take the medication consistently at the same time each day to maintain stable blood levels and ensure continuous blood pressure control. Do not stop taking this medication suddenly, as abrupt discontinuation can cause a dangerous rebound increase in blood pressure and heart rate. If you need to discontinue the medication, your doctor will gradually reduce your dose over time. Regular blood pressure monitoring is essential to assess treatment effectiveness. It may take several weeks to experience the full benefits of this medication, so continue taking it even if you feel well, as high blood pressure often has no symptoms.

• Missed Dose

If you miss a dose of Jitoamlo AT 5/50 Tablet, take it as soon as you remember, provided it is not too close to your next scheduled dose. If it is almost time for your next dose (within 8-10 hours), skip the missed dose and resume your regular dosing schedule. Never take two doses at the same time or take extra medication to make up for a missed dose, as this can lead to excessive blood pressure lowering, extremely slow heart rate, and other serious complications. Taking double doses can result in symptoms such as severe dizziness, fainting, difficulty breathing, or dangerously low blood pressure. If you frequently forget doses, consider setting reminders on your phone, using a pill organizer, or taking your medication at the same time as another daily activity like brushing your teeth. Consistency in taking your blood pressure medication is crucial for maintaining stable blood pressure control and preventing cardiovascular complications. If you miss multiple doses or are unsure what to do, contact your healthcare provider for guidance rather than making dosing decisions on your own.

• Overdose

An overdose of Jitoamlo AT 5/50 Tablet can be serious and requires immediate medical attention. Symptoms of overdose may include severely low blood pressure (hypotension) manifesting as extreme dizziness, lightheadedness, or fainting, dangerously slow heart rate (severe bradycardia), irregular heartbeat, difficulty breathing or shortness of breath, extreme fatigue or weakness, cold and clammy skin, confusion or altered mental state, chest pain, and possible loss of consciousness. The calcium channel blocker component may cause excessive vasodilation leading to profound hypotension, while the beta blocker component can cause severe cardiac depression.

Contraindications of Jitoamlo AT 5/50 Tablet:

Jitoamlo AT 5/50 Tablet is contraindicated in individuals with known hypersensitivity to amlodipine, atenolol, or any excipients. It should not be used in patients with severe hypotension, cardiogenic shock, high-grade aortic stenosis, uncontrolled heart failure, sick sinus syndrome, second- or third-degree heart block, untreated pheochromocytoma, metabolic acidosis, bradycardia below 45 bpm, or severe peripheral arterial disease. Those with haemodynamically unstable heart failure post-myocardial infarction should also avoid it. Always review your medical history with your doctor to confirm if Jitoamlo AT 5/50 contraindications apply to you.

Precautions & Warnings of Jitoamlo AT 5/50 Tablet:

Use Jitoamlo AT 5/50 Tablet with caution in patients with heart failure, as it may increase the risk of pulmonary edema or worsen symptoms; start with lower doses if necessary. In hepatic impairment, the half-life of amlodipine is prolonged, requiring careful dose titration and monitoring. Elderly patients may need slower dose increases due to heightened sensitivity. For individuals with renal issues, no dose adjustment is typically required; however, regular monitoring is recommended. Atenolol components warrant caution in patients with first-degree heart block, diabetes (as it may mask hypoglycemia symptoms), or thyroid issues. Abrupt withdrawal can exacerbate angina or hypertension, so taper off gradually over 7-14 days. During surgery, discuss discontinuation with your anesthesiologist at least 24 hours prior. Jitoamlo AT 5/50 precautions also include avoiding use in reversible obstructive airways disease unless absolutely necessary, and monitoring for hypersensitivity reactions.

Side Effects of Jitoamlo AT 5/50 Tablet:

Common Jitoamlo AT 5/50 side effects include headache, dizziness, fatigue, ankle swelling, flushing, palpitations, and abdominal pain, often occurring at the start of treatment and subsiding over time. Uncommon effects may involve sleep disturbances, mood changes, tremor, nausea, dry mouth, or cold extremities. Rare but serious side effects include allergic reactions, thrombocytopenia, arrhythmias, vasculitis, or hepatic enzyme elevations. Atenolol may cause bradycardia, gastrointestinal disturbances, or visual issues in some cases. If you experience severe Jitoamlo AT 5/50 side effects like chest pain, shortness of breath, or skin rashes, contact your doctor immediately. Reporting adverse events helps improve safety data for this medication.

Safety Relate Concerns of Jitoamlo AT 5/50 Tablet:

• Pregnancy

Jitoamlo AT 5/50 Tablet should be avoided during pregnancy unless the benefits outweigh the risks, as beta-blockers like atenolol are associated with fetal growth restriction and bradycardia. Amlodipine's safety in pregnancy is not fully established, with animal studies showing potential risks. If pregnancy occurs while taking Jitoamlo AT 5/50, discontinue it and consult your doctor for alternative therapies. Women planning pregnancy should discuss switching to safer options beforehand.

• Breastfeeding

Jitoamlo AT 5/50 Tablet is not recommended during breastfeeding, as both amlodipine and atenolol are excreted in breast milk and may cause bradycardia or hypotension in the infant. If use is essential, monitor the baby closely for adverse effects, or consider discontinuing breastfeeding. Always seek medical advice regarding Jitoamlo AT 5/50 breastfeeding compatibility to prioritize infant safety.

• Alcohol

Consuming alcohol while taking Jitoamlo AT 5/50 Tablet may enhance its blood pressure-lowering effects, leading to increased dizziness, hypotension, or fainting. Limit alcohol intake and avoid excessive drinking to prevent these interactions. Discuss your alcohol habits with your doctor when starting Jitoamlo AT 5/50 alcohol precautions.

• Using Machinery & Driving

Jitoamlo AT 5/50 Tablet has minimal impact on driving or operating machinery, but some individuals may experience dizziness, fatigue, or somnolence, especially initially. If these occur, refrain from such activities until you know how the medication affects you. Jitoamlo AT 5/50 driving safety should be assessed personally, and caution is advised for those with jobs requiring alertness.

• Food Interactions

Avoid grapefruit or grapefruit juice while on Jitoamlo AT 5/50 Tablet, as it can increase amlodipine levels, leading to exaggerated blood pressure drops. No other major food interactions are noted, but a balanced diet low in salt supports its efficacy. Consult your doctor about any dietary concerns related to Jitoamlo AT 5/50 food interactions.

• Drug Interactions

Jitoamlo AT 5/50 Tablet may interact with CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) increasing amlodipine exposure, or inducers (e.g., rifampicin) decreasing it; dose adjustments may be needed. It adds to the effects of other antihypertensives, potentially causing excessive lowering. With dantrolene, there's a risk of hyperkalemia. Atenolol may interact with anesthetics, alpha-blockers for pheochromocytoma, or bronchodilators in asthmatics. Monitor tacrolimus or cyclosporine levels if co-administered. Always inform your doctor of all medications to manage Jitoamlo AT 5/50 drug interactions effectively.

Storage Instructions:

Store in a dry place at a temperature not exceeding 25°C. Protect from light. Do not use beyond the expiry date, and dispose of unused medication properly. Keep out of reach of children.

Additional Notes:

• Jitoamlo AT 5/50 Tablet is not intended for self-medication.
• Regular follow-ups with your doctor are crucial to monitor progress and adjust treatment.
• Lifestyle modifications, such as weight management and stress reduction, enhance its effects.
• If symptoms persist or worsen, seek immediate advice.
• Consult healthcare professionals for personalized guidance on Jitoamlo AT 5/50 Tablet other notes.

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Frequently Asked Questions (FAQ):

Q1. What is Jitoamlo AT 5/50 Tablet used for?

A: Jitoamlo AT 5/50 Tablet is primarily used for the treatment of hypertension (high blood pressure). This dual-action combination medication helps lower elevated blood pressure levels and maintain them within a healthy range. By combining a calcium channel blocker and a beta blocker, it addresses high blood pressure through multiple mechanisms, making it particularly effective for patients who do not achieve adequate control with single-drug therapy. The medication reduces the risk of serious cardiovascular complications associated with uncontrolled hypertension, including heart attacks, strokes, kidney damage, and heart failure. Some doctors may also prescribe it for angina (chest pain) management, though this is not its primary indication. The medication provides comprehensive cardiovascular protection by controlling both blood pressure and heart rate simultaneously.

Q2. Can Jitoamlo AT 5/50 Tablet be taken daily for long-term use?

A: Yes, Jitoamlo AT 5/50 Tablet can be taken daily and is specifically designed for long-term use in managing chronic hypertension. Hypertension is a lifelong condition that requires continuous management to prevent complications. This medication provides stable, 24-hour blood pressure control when taken once daily, making it convenient for long-term adherence. Most patients take this medication indefinitely as part of their ongoing cardiovascular health management. Regular monitoring by your healthcare provider ensures the medication remains effective and safe for you over time. Never discontinue the medication without medical supervision, even if your blood pressure readings are normal, as this indicates the medication is working effectively. Stopping suddenly can cause dangerous rebound hypertension. Long-term use is safe under proper medical supervision, with periodic evaluation of blood pressure, heart rate, kidney function, and liver function to ensure continued appropriate use.

Q3. What should I do if I experience dizziness or lightheadedness while taking this medication?

A: Dizziness and lightheadedness are common side effects when starting Jitoamlo AT 5/50 Tablet or after dose increases, as your body adjusts to lower blood pressure levels. To manage these symptoms, always rise slowly from sitting or lying positions, giving your cardiovascular system time to adjust to position changes. Sit on the edge of the bed for a moment before standing up in the morning. Stay well-hydrated by drinking adequate fluids throughout the day. Avoid sudden movements, hot environments, and prolonged standing, which can exacerbate symptoms. If you feel dizzy, sit or lie down immediately until the feeling passes. Avoid driving or operating machinery until you know how the medication affects you. Most patients find these symptoms improve within 1-2 weeks as their body adapts. However, if dizziness is severe, persistent, associated with fainting episodes, or interferes with daily activities, contact your healthcare provider. Your doctor may need to adjust your dose, check for underlying causes, or rule out excessive blood pressure lowering. Never stop the medication abruptly without medical guidance, as this can cause rebound hypertension.

Q4. Can I take Jitoamlo AT 5/50 Tablet if I have diabetes?

A: Patients with diabetes can take Jitoamlo AT 5/50 Tablet, but extra caution and monitoring are necessary. Beta blockers like Atenolol can affect blood sugar regulation and mask the warning signs of hypoglycemia (low blood sugar), such as rapid heartbeat, trembling, and anxiety. The only symptoms that may remain noticeable are sweating and dizziness, so you must be vigilant about monitoring blood glucose levels more frequently, especially when starting the medication or adjusting doses. Check your blood sugar as recommended by your healthcare provider and be prepared to treat low blood sugar promptly if it occurs. Inform your doctor about your diabetes so they can coordinate your blood pressure and diabetes management. Your diabetes medication doses may need adjustment.

Q5. What is the difference between Jitoamlo AT 5/50 Tablet and taking Amlodipine and Atenolol separately?

A: Jitoamlo AT 5/50 Tablet combines Amlodipine and Atenolol in one pill, while taking them separately means using two tablets. The main benefit of the combination tablet is convenience—one pill instead of two—making it easier to take medicines regularly. Better adherence helps maintain stable blood pressure and lowers heart-related risks. It also reduces pill burden and may be more cost-effective in some cases. The fixed-dose combination provides both medicines in consistent, approved proportions. However, separate tablets offer more flexibility, as doctors can adjust each drug dose individually and manage side effects more easily. Your doctor will choose the best option based on your health needs and response to treatment.