Itranext 100 mg Capsule (10 Cap)

Itranext 100 Capsule Overview:

Itranext 100 Capsule is an anti-fungal medicine, used to treat a wide range of fungal infections which can affect different parts of the body, such as the skin, nails, lungs, mouth, vagina and even internal organs. Itranext 100 Capsule not only helps to treat fungal infections but also plays a crucial role in preventing them from coming back. By targeting and inhibiting the growth of fungi, Itranext 100 Capsule ensures that infections are effectively controlled and reduced over time.

Composition of Itranext 100 Capsule:

Each hard gelatin Itranext 100 Capsule contains: Itraconazole 100 mg (as pellets) and Excipients q.s.

Approved colour used in empty capsule shells.

Uses and Benefits of Itranext 100 Capsule:

Itranext 100 Capsule is used for the treatment of fungal infections including:

• Dermatophyte Infections: such as ringworm, athlete's foot and jock itch.

• Candidiasis: fungal infections caused by Candida species (e.g., oral thrush, vaginal yeast infections).

• Systemic fungal Infections: Like histoplasmosis, blastomycosis, or aspergillosis, which affect the respiratory system as well as other internal organs such as liver, heart, brain or kidneys.

• Onychomycosis: fungal infections of the nails.

Itranext 100 Capsule also helps in preventing the recurrence of fungal infections, especially in people with weakened immune systems or those with HIV/AIDS.

How Itranext 100 Capsule Works:

Itranext 100 Capsule contains Itraconazole, a well-known antifungal medicine. It works by stopping the fungus from building a protective layer called ergosterol, which is needed for fungal cells to survive. When this layer is weakened, the fungal cells become damaged, cannot grow properly, and eventually die.

By blocking fungal growth and spreading, Itranext 100 Capsule helps clear the infection and prevents it from getting worse or coming back.

Dosage of Itranext 100 Capsule:

• Usage Direction

Take Itranext 100 Capsule exactly as prescribed by your doctor, and follow the recommended dosage and schedule. Itranext 100 Capsule should be swallowed as a whole without crushing, chewing, or breaking it. It is best to take it with food and at the same time every day so the medicine works properly.

Do not stop or alter the dose of Itranext 100 Capsule without consulting your doctor, as this may prevent you from achieving the desired outcome. Complete the full course, even if you begin to feel better. The fungus may still be present in the body, and stopping too soon can lead to the infection returning or becoming harder to treat later. Ask your doctor or pharmacist to explain any administration procedure you do not understand.

 • Missed Dose

If you miss a dose of Itranext 100 Capsule, take it as soon as it is remembered. If it is time for your next dose of Itranext 100 Capsule, skip the missed dose and resume your regular schedule. Avoid taking double doses to make up for the missed one. Never double up on doses, as this could heighten side effect risks without improving efficacy against fungal infections.

 • Overdose

Taking more than the recommended dose of Itranext 100 Capsule may lead to serious side effects that require immediate medical help. Symptoms of overdose might include severe nausea, vomiting, dizziness, or abdominal pain, potentially signaling liver strain. Contact emergency services or your local poison control center right away—do not wait for symptoms to worsen.

Contraindications of Itranext 100 Capsule:

Do not take Itranext 100 Capsule if you are hypersensitive or allergic to Itraconazole, any of the ingredients of this medicine, or other antifungal medications. Consult with your doctor during taking Itranext 100 Capsule if you have severe liver disease, or congestive heart failure.

Precautions & Warnings of Itranext 100 Capsule:

Before starting Itranext 100 Capsule, inform your doctor if you have liver or kidney disease, heart problems, weak immunity (like AIDS), or low stomach acid. Your doctor may advise regular check-ups, especially to monitor liver health, as this medicine can sometimes affect liver function. Seek help if you notice yellow skin or eyes, extreme tiredness, or dark urine.

People with heart issues should be alert to swelling, breathing difficulty, or sudden weight gain. Those with conditions like cystic fibrosis or reduced immunity may need closer monitoring, as absorption can vary. If you feel numbness or tingling in your hands or feet, report it promptly. Elderly patients or those with kidney concerns may require dose adjustments. Regular medical guidance helps ensure safe and effective treatment.

Side Effects of Itranext 100 Capsule:

Itranext 100 Capsule may cause some side effects, most of which are mild and typically go away as your body adjusts to the medication. However, if these symptoms continue, it is important to consult your doctor. These side effects include diarrhea, constipation, gas, bloating, heartburn, stomach pain, unpleasant taste, headache, and sweating. In some cases, more serious side effects may occur and require medical attention, such as ringing in the ears, difficulty controlling urination or urinating more frequently, numbness, tingling, burning, or a crawling sensation on the skin, and persistent pain starting in the stomach area that may spread to the back.

Safety Related Concerns of Itranext 100 Capsule:

 • Pregnancy

Do not take Itranext 100 Capsule if you are pregnant or planning to become pregnant unless your doctor says to take this. Animal studies have shown birth defects and although human studies are limited and mixed, there is some evidence of higher rates of miscarriage with first-trimester exposure. For routine problems such as ringworm or nail fungus, safer options (like topical treatments) are usually preferred during pregnancy.

 • Breastfeeding

Breastfeeding mothers are advised to avoid Itranext 100 Capsule as it may pass through breast milk and can cause side effects in breastfed babies. Therefore, it is important to consult your doctor before taking Itranext 100 Capsule while breastfeeding.

• Alcohol Interaction

It is recommended to avoid drinking alcohol while taking Itranext 100 Capsule. If you are being treated for fungal infections, drinking regularly can weaken the body’s immune response and may slow down recovery.

 • Food Interactions

It is recommended to avoid drinking grape fruit juice while taking Itranext 100 Capsule.

Consult your doctor if you are taking any herbal products or supplements while taking Itranext 100 Capsule. If found any other complications, please consult with your physician immediately.

• Drug Interactions

Itranext 100 Capsule can interact with several medicines, so always inform your doctor about everything you take.

Some medicines like simvastatin (for cholesterol), calcium channel blockers such as verapamil (for heart conditions), and strong pain medicines like methadone can become too strong and cause side effects when taken with Itranext 100 Capsule. Warfarin may increase bleeding risk and needs close monitoring.

Medicines that reduce stomach acid, such as antacids, omeprazole, or pantoprazole, can lower the absorption of this Itraconazole capsule, so your doctor may advise different timing. Drugs like rifampicin (TB treatment) or phenytoin (for seizures) may reduce its effectiveness.

Always share your full medication list to ensure safe and effective treatment with this antifungal medicine.

Label Caution- Terfenadine or Astemizole should not be taken simultaneously when the patient is on this medication.

• Driving

If you experience side effects such as dizziness or blurred vision, you should avoid driving or operating machinery while taking Itranext 100 Capsule.

Storage of Itranext 100 Capsule:

Itranext 100 Capsule should be stored in a cool, dry & dark place.

Do not use Itranext 100 Capsule past its expiration date printed on the package. Dispose of expired or unused medications properly according to local guidelines or take them to a pharmacy take-back program. Keep Itranext 100 Capsule out of reach of children.

Frequently Asked Questions (FAQs):

Q1. Is Itranext 100 and Itraconazole are same?

A: Yes, Itranext 100 and Itraconazole are the same in terms of their active ingredient, which are an antifungal drug used to treat various fungal infections. Itranext 100 is a specific brand name or formulation of Itraconazole. Always check with your doctor or pharmacist to ensure you are using the right medication for your condition.

Q2. Is Itranext 100 Capsule a steroid?

A: No, Itranext 100 Capsule is not a steroid. It is an antifungal medication that contains Itraconazole, which is used to treat fungal infections. Steroids, on the other hand, are a class of drugs that typically reduce inflammation or suppress the immune system.

Q3. What foods should you avoid when taking Itranext 100 Capsule?

A: Itranext 100 Capsule contain Itraconazole, which may interact with certain foods and substances, potentially causing side effects. These include grapefruit and grapefruit juice, alcohol, caffeine, and antacids. Always follow your doctor's guidance regarding food and drink while taking this medication.

Q4. Is Itranext 100 Capsule safe during pregnancy?

A: Itranext 100 Capsules may not be safe during pregnancy, particularly in the first trimester, as they could harm the unborn baby. Inform your healthcare provider immediately if you are pregnant or become pregnant while taking Itraconazole Capsules.

Q5. How long does Itranext 100 Capsule take for antifungal treatment to work?

A: The time it takes for Itranext 100 Capsule to work depends on the severity and location of the infection. For mild infections, you may start to see improvement within a few days, while more severe infections may take several weeks to fully resolve. If you don't see any improvement after taking the medication, consult your doctor right away.

Q6. Can Itranext 100 Capsule be taken with other medications?

A: Itranext 100 Capsule can interact with other medications, as this may cause side effects or reducing the effectiveness of treatment. These include other antifungal drugs (such as fluconazole, ketoconazole, posaconazole, voriconazole, isavuconazonium), antacids, calcium channel blockers (like dihydropyridines and verapamil), anticoagulants, HIV protease inhibitors (such as ritonavir, indinavir, and saquinavir), as well as vitamins, supplements, or herbal products. Always inform your doctor about any other medications you are taking with Itranext 100 Capsule.

Q7: Are there foods, drinks or other medicines I should avoid while using Itranext 100 Capsule?

A: Yes, avoid grapefruit/grapefruit juice, limit alcohol, and avoid or space out antacids or acid-reducing medications, as these may interfere with Itraconazole absorption or increase risk of side effects. Always inform your doctor about any other medications or supplements you take.

References:

1. Itraconazole. MedlinePlus. Last Revised: April 15, 2023. Accessed on 01.03.2025. Click Here

2. Patient Information: Itraconazole. Accessed on 01.03.2025. Click Here

3. Kurn H, Wadhwa R. Itraconazole. [Updated 2023 Apr 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Click Here

4. ITRACLAR SB. Last Revised: Jun 21. Accessed on 01.03.2025. Click Here