Glyree M Forte 1 mg Tablet (10 Tab)

Glyree M 1 Forte Tablet Overview:

Glyree M 1 Forte Tablet is an oral anti diabetic medicine, used to treat Type II diabetes mellitus.

It is used in patients whose body either does not produce enough insulin or the cells do not respond properly to insulin, leading to high blood sugar levels known as hyperglycemia. This medication is prescribed along with proper diet and physical exercise to improve glycemic control in patients whose diabetes is not well-controlled with a single oral anti diabetic medicine.

Composition of Glyree M 1 Forte Tablet:

Each uncoated tablet contains: Metformin Hydrochloride (As prolonged-release) 1000 mg, Glimepiride 1 mg and Excipients: q.s.

Colour: Ponceau 4R .

Uses and Benefits of Glyree M 1 Forte Tablet:

Glyree M 1 Forte Tablet is used for the treatment of Type II diabetes mellitus or non-insulin-dependent diabetes mellitus (NIDDM).

How Glyree M 1 Forte Tablet Works:

Glyree M 1 Forte Tablet is a combination of two anti diabetic medications, glimepiride and metformin. Together they help improve glycemic control in type II diabetes mellitus patients.

Glimepiride, a sulfonylurea, lowers blood sugar by stimulating the pancreas to release more insulin. Meanwhile, metformin, a biguanide, works by decreasing the liver's glucose production, slowing the absorption of glucose in the intestines, and enhancing the body's response to insulin.

Dosage of Glyree M 1 Forte Tablet:

• Usage Direction

Take Glyree M 1 Forte Tablet exactly as prescribed by your doctor, and follow the recommended dosage and schedule. Glyree M 1 Forte should be swallowed as a whole without crushing, chewing, or breaking it, and ideally at the same time each day. Do not stop or alter the dose of Glyree M 1 Forte Tablet without consulting your doctor, as this may prevent you from achieving the desired outcome. Regular monitoring of your blood and urine while taking Glyree M 1 Forte Tablet may improve your condition. Ask your doctor or pharmacist to explain any administration procedure you do not understand.

• Missed Dose

If you miss a dose of Glyree M 1 Forte Tablet, take it as soon as it is remembered. If it is time for your next dose of Glyree M 1 Forte Tablet, skip the missed dose and resume your regular schedule. Avoid taking two doses to compensate for a missed one.

• Over Dose

If you accidentally take Glyree M 1 Forte Tablet more than your prescribed dose, it may lead to severe hypoglycemia. To manage hypoglycemia in an emergency basis, take fast-acting carbohydrates like sugar, fruit juice, honey, etc and seek medical advice immediately.

Contraindications of Glyree M 1 Forte Tablet:

Do not take Glyree M 1 Forte Tablet, if you are hypersensitive or allergic to glimepiride, metformin, or any of the components of this medicine or if you have Type 1 or insulin-dependent diabetes mellitus, diabetic ketoacidosis, diabetic coma, decompensated heart failure, respiratory failure or recent myocardial infarction, severe kidney or liver disease.

Precautions & Warnings of Glyree M 1 Forte Tablet:

Before starting Glyree M 1 Forte Tablet, tell your doctor if you have an increased risk of cardiovascular-related mortality, irregular meal time, or hormone-induced disorders. It is recommended to avoid foods and drinks which are high in sugar.

Side Effects of Glyree M 1 Forte Tablet:

Glyree M 1 Forte Tablet may also cause some side effects, most of which do not require medical attention and typically go away as your body adapts to the medication. These may include nausea, diarrhea, abdominal pain, constipation, vomiting and a metallic taste in the mouth. However, if these side effects persist, consult your doctor as soon as possible. Some of the side effects may also be serious and may need medical attention such as; hypoglycaemia, lactic acidosis, feeling of being sick, diarrhoea, bloating, abdominal pain and allergic reaction.

Safety Related Concerns of Glyree M 1 Forte Tablet:

• Pregnancy

If you are planning to become pregnant or if a pregnancy is discovered, it's important to consult with your doctor to determine whether it is safe for you to continue with Glyree M 1 Forte Tablet. Gestational diabetes, which occurs during pregnancy, carries an increased risk of birth defects. Therefore, your doctor may recommend switching to insulin therapy to better control blood sugar levels. It is essential to monitor blood glucose levels closely throughout pregnancy to minimize the risk of fetal malformations.

• Breastfeeding

Breastfeeding mothers are advised to avoid Glyree M 1 Forte Tablet as it may pass through breast milk and can cause side effects in breastfed babies. Therefore, it is important to consult your doctor before taking Glyree M 1 Forte while breastfeeding.

• Alcohol

It is recommended to avoid drinking alcohol while taking Glyree M 1 Forte Tablet, as it can increase the risk of low blood sugar (hypoglycemia) and may also cause lactic acidosis.

• Food or Interactions with Other Medicines

Carbohydrate-rich foods (such as sugary foods) and high-fat foods should be avoided while taking Glyree M 1 Forte Tablet.

Consult your doctor if you are taking any herbal products or supplements while taking Glyree M 1 Forte Tablet. As always, it is a good idea to consult your doctor or healthcare provider about your specific dietary needs while on Glyree M 1 Forte Tablet.

• Driving

If you experience side effects such as dizziness or blurred vision, you should avoid driving or operating machinery while taking Glyree M 1 Forte Tablet.

Storage of Glyree M 1 Forte Tablet:

Glyree M 1 Forte Tablet,should be protected from light & moisture, at a temperature not exceeding 30ºC.

Keep Glyree M 1 Forte Tablet out of reach of children.

Note: Regular exercise and a healthy diet may improve your condition.

Frequently Asked Questions (FAQs) about Glyree M 1 Forte Tablet:

1. What is Glyree M 1 Forte Tablet used for?

Glyree M 1 Forte Tablet is used for the treatment of Type II diabetes mellitus.

Glyree M 1 Forte Tablet is used along with proper diet and physical exercise to improve glycemic control in patients, especially for whose diabetes is not adequately controlled with single oral anti diabetic medicine.

2. Does Glyree M 1 Forte Tablet lead to hypoglycemia?

Glyree M 1 Forte Tablet is usually recommended for managing Type II diabetes mellitus. However, taking more than the prescribed dose or using it alongside other anti diabetic medications can lead to dangerously low blood sugar levels, a condition known as hypoglycemia.

3. Is Glyree M 1 Forte Tablet an insulin?

No, Glyree M 1 Forte Tablet is not an insulin. While insulin is a hormone, Glyree M 1 Forte Tablet is a combination of two oral anti diabetic drugs: Glimepiride and Metformin. It is commonly prescribed to individuals with type 2 diabetes to help regulate blood sugar levels.

4. What is the difference between Glycomet Tablet and Glyree M 1 Forte Tablet?

The primary difference between Glycomet Tablet and Glyree M 1 Forte Tablet lies in their composition, both of which are used to treat Type II diabetes mellitus. Glyree M 1 Forte Tablet combines Glimepiride and Metformin, while Glycomet Tablet contains only Metformin. It is essential to take only the medication prescribed by your doctor according to your physical condition and avoid self-medication.

5. What happens if blood sugar drops too quickly?

When blood sugar levels drop too quickly, it can result in hypoglycemia. Symptoms may include shaking or trembling, dizziness, weakness, a rapid heart rate, sweating, and chills. In severe cases, it can cause confusion, seizures, or even coma, which can be life-threatening. To manage hypoglycemia in an emergency basis by consuming fast-acting carbohydrates such as glucose tablets, sugary products, or regular soda to restore blood sugar to normal levels.

6. Which food should avoid during this medication?

While using Glyree M 1 Forte Tablet, it is advisable to avoid foods and drinks high in natural or added sugars, such as fruit juice, soda, candy, desserts, white bread, rice, chips, sugary cereals, ice cream, and sweetened milk. Additionally, alcohol should be avoided during this treatment as it can lower blood sugar levels, increasing the risk of hypoglycemia, and may also raise the likelihood of developing lactic acidosis.

7. Can Glyree M 1 Forte Tablet cause weight gain?

Yes, Glyree M 1 Forte Tablet may cause weight gain due to its ingredient Glimepiride, which belongs to the Sulfonylureas class of medications. Sulfonylureas work by stimulating the pancreas to produce more insulin, which helps lower blood sugar levels. However, insulin also promotes fat storage in the body. As a result, increased insulin levels can lead to the storage of more fat, potentially causing weight gain. If you're concerned about weight gain while taking Glyree M 1 Forte  Tablet, it is important to discuss it with your healthcare provider. They can adjust your treatment plan to help manage both your blood sugar and weight.

References:

1. METFORMIN + GLIMEPIRIDE. Contents. Glimepiride 2 mg, metformin HCl 500 mg. Accessed on 05.02.2025. Click Here

2. PATIENT INFORMATION LEAFLET. ILET B. Accessed on 05.02.2025. Click Here

3. AZULIX MF (Glimepiride and Metformin Hydrochloride Sustained Release Tablets). Last Revised - January 2016. Accessed on 05.02.2025. Click Here

4. Metformin. Last Revised - 02/15/2024. Accessed on 05.02.2025. Click Here