Glizid M Tablet (15 Tab)

Glizid M Tablet Overview:

Glizid M Tablet is an oral anti diabetic medication designed specifically for managing type 2 diabetes, where diet and exercise alone aren't enough to keep blood sugar in check. The tablet works through a dual mechanism, addressing multiple aspects of blood sugar regulation simultaneously. It is prescribed for patients whose diabetes cannot be adequately managed through lifestyle interventions or single-agent therapy, offering a convenient single-tablet approach to comprehensive glycemic control. Consistent use can help prevent or delay many complications associated with uncontrolled blood sugar. It is not meant for type 1 diabetes or urgent situations like ketoacidosis, where different care is required.

Composition:

Each uncoated tablet contains- Gliclazide: 80 mg and Metformin Hydrochloride: 500 mg.

Uses & Benefits of Glizid M Tablet:

The combined formulation of Glizid M Tablet offers several therapeutic advantages-

• Controls elevated blood glucose levels effectively in adults with type 2 diabetes mellitus

• Reduces the risk of long-term diabetic complications affecting the kidneys, nerves, and eyes

• Improves overall glycemic control when diet and exercise alone are insufficient

• Addresses both inadequate insulin secretion and insulin resistance simultaneously

How Glizid M Tablet Works:

Glizid M Tablet employs a dual-action mechanism to regulate blood glucose levels. The Gliclazide component stimulates pancreatic beta cells to release insulin by binding to specific receptors, helping restore impaired insulin secretion characteristic of type 2 diabetes. It also reduces liver glucose production and improves glucose clearance from the bloodstream. The Metformin Hydrochloride component primarily reduces glucose production in the liver, decreases glucose absorption from the intestines, and enhances insulin sensitivity in muscle tissues. This improved responsiveness allows cells to uptake glucose more effectively. Together, both components work synergistically to maintain stable blood glucose levels throughout the day, addressing multiple metabolic abnormalities present in type 2 diabetes.

Dosage of Glizid M Tablet:

• Usage Directions

Glizid M Tablet should be administered orally with meals to minimize gastrointestinal discomfort. The tablet must be swallowed whole with water and should never be crushed, chewed, or broken. Take the medication at consistent times daily to maintain steady levels. Dosage and adjustments should be determined exclusively by your healthcare provider based on blood glucose monitoring, treatment response, and overall health status. Never alter your prescribed dose without consulting your physician.

• Missed Dose

If a scheduled dose is missed, take it as soon as remembered unless it is close to the next scheduled dose. When timing is near the next dose, skip the forgotten dose entirely and resume the normal schedule. Never take double doses to compensate for a missed dose, as this significantly increases the risk of adverse effects, particularly hypoglycemia. If you frequently forget doses, discuss strategies with your healthcare provider to improve medication adherence, such as using pill organizers or setting smartphone reminders to maintain consistent treatment.

• Overdose

Overdose constitutes a medical emergency requiring immediate intervention. Excessive intake can cause severe hypoglycemia with symptoms including excessive sweating, trembling, rapid heartbeat, confusion, hunger, dizziness, and potentially loss of consciousness or seizures. The Metformin component may precipitate lactic acidosis, characterized by unusual muscle pain, difficulty breathing, severe drowsiness, stomach discomfort, feeling cold, and irregular heartbeat. Anyone suspected of overdose should seek emergency medical attention immediately. Call emergency services or visit the nearest hospital, bringing the medication container to help healthcare providers determine the amount ingested. Treatment may involve intravenous glucose and supportive care.

Contraindications of Glizid M Tablet:

Glizid M Tablet is contraindicated in several conditions where use poses significant risks. Do not use if you have hypersensitivity to Gliclazide, Metformin, or any of it’s components. It is contraindicated in type 1 diabetes, diabetic ketoacidosis, severe kidney or liver impairment. Avoid use in acute conditions with tissue hypoxia including severe heart failure, respiratory failure, recent heart attack, or sepsis. The medication is contraindicated in diabetic pre-coma, metabolic acidosis, severe infections, pregnancy, and breastfeeding. Chronic alcoholism also contraindicates use. These conditions significantly increase risks of lactic acidosis and other serious complications requiring alternative treatment approaches.

Precautions & Warnings of Glizid M Tablet:

Patients with mild to moderate kidney impairment require careful monitoring and potential dose adjustments with regular renal function assessment. Those with liver dysfunction need close supervision. Elderly patients warrant special attention due to potentially reduced kidney function and higher risks of hypoglycemia. Use cautiously in cardiovascular disease patients. Temporarily discontinue before surgery requiring general anesthesia and before radiological procedures involving iodinated contrast dyes, resuming only after confirming normal kidney function. Monitor vitamin B12 levels during prolonged therapy. Patients should recognize hypoglycemia symptoms and carry quick sugar sources. Inform your physician about severe infections, dehydration, or trauma. Avoid excessive alcohol. Women of childbearing potential should use effective contraception.

Side Effects of Glizid M Tablet:

Common side effects include gastrointestinal effects like nausea, vomiting, diarrhea, abdominal pain, stomach upset, metallic taste, loss of appetite, and constipation. These often occur when starting therapy and can be minimized by taking medication with food. Hypoglycemia symptoms include shakiness, sweating, rapid heartbeat, hunger, confusion, and dizziness, particularly if meals are skipped. Headache, upper respiratory infections, and weakness may also occur. Serious side effects requiring immediate medical attention include lactic acidosis symptoms such as unusual muscle pain, severe tiredness, difficulty breathing, stomach pain with nausea, feeling cold, or slow heart rate. Skin reactions, blood disorders, liver problems, and visual disturbances also warrant urgent evaluation.

Safety Relate Concerns of Glizid M Tablet:

• Pregnancy

Glizid M Tablet is not recommended during pregnancy due to insufficient safety data and potential fetal risks. Uncontrolled diabetes during pregnancy carries significant risks, including congenital abnormalities and maternal-fetal complications. However, this combination medication safety profile during pregnancy remains inadequately established. When planning pregnancy or discovering pregnancy, immediately consult your healthcare provider. The standard recommendation involves transitioning to insulin therapy before conception or upon pregnancy confirmation. Insulin remains the preferred option for managing diabetes during pregnancy, as it provides optimal blood glucose control without crossing the placental barrier. Close monitoring and strict glycemic control throughout pregnancy are crucial. Never discontinue or modify diabetes medication without medical guidance.

• Breastfeeding

Breastfeeding moms face choices that balance nourishment and health, and Glizid M Tablet requires caution, as its components may enter breast milk in small amounts, possibly affecting the baby's blood sugar levels. Though quantities are low, monitoring for infant drowsiness or feeding issues is wise if use continues briefly. Insulin or metformin alone might suit better, per your doctor's call.

• Alcohol

Alcohol consumption is strongly discouraged during therapy due to multiple serious interaction risks. The combination significantly increases lactic acidosis risk, a potentially fatal condition where lactic acid accumulates dangerously. Alcohol itself raises lactic acid levels, compounded when combined with Metformin. Additionally, alcohol causes unpredictable blood glucose fluctuations. The Gliclazide component combined with alcohol can precipitate severe hypoglycemia, with alcohol-related symptoms masking low blood sugar warning signs. Chronic heavy alcohol use increases liver damage risk, impairing medication metabolism and further elevating lactic acidosis risk. Strictly limit or completely avoid alcoholic beverages.

• Using Machinery & Driving

Glizid M Tablet may affect the ability to safely operate vehicles or machinery, requiring appropriate caution. While it doesn't directly impair cognitive or motor function when blood glucose is well-controlled, the primary concern relates to potential hypoglycemia, which significantly compromises alertness, concentration, coordination, and reaction time.

• Food Interactions

Maintain a consistent, balanced diabetes-appropriate diet limiting simple sugars and refined carbohydrates while emphasizing whole grains, vegetables, lean proteins, and healthy fats. Regular meal timing prevents hypoglycemia; avoid skipping meals or significantly delaying eating times. Excessive high-sugar foods can overwhelm medication's glucose-controlling capacity, while very low-carbohydrate diets may increase hypoglycemia risk. Discuss all dietary choices with your healthcare provider.

Storage Instructions:

Store at a temperature not more than 30°C. Protect from light and moisture.

Other Notes:

Regular blood glucose monitoring is essential to assess medication effectiveness. Maintaining a balanced diet and engaging in regular physical activity remain crucial components of comprehensive diabetes management alongside medication therapy.

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Frequently Asked Questions (FAQs):

Q: What is Glizid M Tablet used for?

A: Glizid M Tablet helps manage type 2 diabetes by lowering blood sugar, often when diet and exercise need a boost, or alongside other treatments like insulin.

Q: How do I take Glizid M Tablet safely?

A: Swallow the tablet with a meal as prescribed, with water—your doctor tailors the schedule to fit your routine smoothly.

Q: Does Glizid M Tablet lead to weight changes?

A: It tends to keep weight steady, thanks to metformin's neutral effect, making it a steady pick for balanced management.

Q: Can Glizid M Tablet cause stomach issues?

A: Yes, some feel nausea or diarrhea at first, but taking with food often eases it; tell your doctor if it sticks around.

Q: Is Glizid M Tablet okay with other diabetes meds?

A: It works well with many, but combos like insulin raise low sugar watches—your provider will guide adjustments.

Q: What if I forget a Glizid M Tablet dose?

A: Take it soon if remembered early, but skip and resume normally if near the next—never double to stay safe.

Q: How does Glizid M Tablet affect daily energy?

A: By stabilizing sugars, it often brings more even energy, cutting fatigue from highs and lows over time.