Damita M 10/500 mg Tablet (15 Tab)

Damita M 10/500 Tablet Overview:

Damita M 10/500 Tablet is a combination antidiabetic medication specifically designed to treat type-2 diabetes mellitus in adults. This prescription medication combines two powerful active ingredients to provide comprehensive blood sugar control when used alongside proper diet and exercise. The medication not only helps control high blood sugar levels but also reduces the risk of serious diabetic complications and helps prevent heart disease. Additionally, Dapabite M lowers the risk of heart failure in type 2 diabetic patients with existing heart conditions. This combination therapy is particularly beneficial for patients whose diabetes cannot be adequately controlled with single medications or lifestyle modifications alone.

Composition:

Each film-coated bilayered tablet contains: Dapagliflozin Propanediol Monohydrate Eqv. To Dapgliflozin 10 mg, Metformin Hydrochloride 500 mg (Extended Release) and Excipients q.s.

Colour: Titanium Dioxide & Ferric Oxide Yellow

Uses & Benefits of Damita M 10/500 Tablet:

The primary benefits of Damita M 10/500 Tablet extend beyond simple blood sugar reduction. Proper blood sugar control helps prevent serious diabetic complications, including kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. The medication provides dual-action benefits by addressing glucose control through two different mechanisms simultaneously. Patients often experience improved energy levels, reduced excessive thirst and urination, and better overall quality of life. The medication also provides cardiovascular protection by reducing the risk of heart failure in diabetic patients with heart disease. Weight management may also improve as SGLT2 inhibitors can contribute to modest weight loss through glucose excretion.

How Damita M 10/500 Tablet Works:

Damita M 10/500 Tablet works through multiple mechanisms: reducing glucose production in the liver, increasing glucose excretion in the urine, and improving insulin sensitivity in the body. Dapagliflozin blocks SGLT2 receptors in the kidneys, preventing glucose reabsorption and allowing excess sugar to be eliminated through urine. This process is insulin-independent, making it effective even in insulin-resistant conditions. Metformin primarily works by suppressing hepatic glucose production and enhancing peripheral glucose uptake by improving insulin sensitivity. The combination provides complementary actions that result in more comprehensive glucose control than either medication alone. This dual mechanism approach targets multiple pathways involved in diabetes pathophysiology.

Dosage of Damita M 10/500 Tablet:

• Usage Directions

Damita M 10/500 Tablet should be taken exactly as prescribed by your healthcare provider. The medication is typically taken once daily with or without food, preferably at the same time each day to maintain consistent blood levels. Swallow the tablet whole without crushing, chewing, or breaking it. Regular blood sugar monitoring is essential while taking this medication. Your doctor may adjust the dosage based on your blood sugar levels, kidney function, and overall health condition. Always maintain prescribed diet and exercise regimens alongside medication therapy. Stay adequately hydrated while taking this medication, as SGLT2 inhibitors can increase urination.

• Missed Dose

If you miss a dose of Damita M 10/500 Tablet, take it as soon as you remember, provided it's not close to your next scheduled dose. If it's nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Never take double doses to make up for a missed dose, as this can increase the risk of side effects and complications. If you frequently forget doses, consider setting reminders or using a pill organizer. Discuss missed dose management strategies with your healthcare provider, especially if you miss doses regularly. Consistent medication adherence is crucial for optimal diabetes management and preventing complications.

• Overdose

Overdose of Damita M 10/500 Tablet can be serious and requires immediate medical attention. Signs of overdose may include severe hypoglycemia, lactic acidosis from the metformin component, excessive urination, dehydration, and electrolyte imbalances. If overdose is suspected, contact emergency medical services immediately or go to the nearest hospital. Do not induce vomiting unless specifically instructed by medical professionals. Bring the medication container with you to help medical staff understand the extent of overdose. Treatment typically involves supportive care, blood sugar monitoring, and correction of metabolic imbalances. Prevention through proper dosing and storage away from children is essential.

Contraindications of Damita M 10/500 Tablet:

Damita M 10/500 Tablet is contraindicated in patients with acute renal failure or history of lactic acidosis. The medication should not be used in patients with type 1 diabetes, diabetic ketoacidosis, or severe kidney disease. Patients with active liver disease or alcoholism should avoid this medication due to the increased risk of lactic acidosis. The medication is not recommended during pregnancy or breastfeeding. Patients with severe heart failure requiring hospitalization should not use this medication. Hypersensitivity to dapagliflozin, metformin, or any component of the formulation is also a contraindication. Patients scheduled for surgery or imaging procedures requiring contrast agents may need temporary discontinuation.

Precautions & Warnings of Damita M 10/500 Tablet:

Several important precautions must be observed while using Damita M 10/500 Tablet. Elderly patients require special caution as they are more likely to have kidney, liver, or heart problems, which may require dose adjustments. Regular monitoring of kidney function is essential, as both components can affect renal function. Patients should be alert for signs of urinary tract infections and genital infections, which are more common with SGLT2 inhibitors. Dehydration risk is increased, particularly in elderly patients or those taking diuretics. Blood sugar can go too low when combined with other diabetes medications, including insulin or sulfonylureas. Alcohol consumption should be limited or avoided as it can alter glycemic control and increase toxicity. Patients should be educated about recognizing signs of lactic acidosis.

Side Effects of Damita M 10/500 Tablet:

Common side effects of Damita M 10/500 Tablet include urinary tract infections, genital yeast infections, increased urination, and mild gastrointestinal symptoms such as nausea, vomiting, or diarrhea. Hypoglycemia (low blood sugar) can occur, especially when used with other diabetes medications. Some patients may experience dizziness, headache, or fatigue during initial treatment. Serious but rare side effects include lactic acidosis, which presents with muscle pain, breathing difficulties, stomach pain, and weakness. Diabetic ketoacidosis, though uncommon, can occur and requires immediate medical attention. Dehydration and electrolyte imbalances may occur due to increased urination. Any persistent or severe side effects should be reported to healthcare providers immediately for proper evaluation and management.

Safety Related Advices of Damita M 10/500 Tablet:

• Pregnancy

Damita M 10/500 Tablet should be avoided during pregnancy. There are no adequate studies in women for determining infant risk when using this medication during pregnancy. The medication crosses the placental barrier and may affect fetal development. Women of childbearing age should use effective contraception while taking this medication and discuss pregnancy planning with their healthcare provider. If pregnancy occurs during treatment, the medication should be discontinued immediately and alternative diabetes management strategies implemented. Insulin is typically the preferred treatment for diabetes during pregnancy. Blood sugar control remains important during pregnancy, but safer alternatives should be used under medical supervision.

• Breastfeeding

The use of Damita M 10/500 Tablet during breastfeeding requires careful consideration, as there are no adequate studies determining infant risk. Metformin should be used with caution while nursing newborn and premature infants and those with renal impairment, while dapagliflozin should be avoided during the first two years of life. Healthcare providers must weigh potential benefits against potential risks before prescribing this medication to breastfeeding mothers. If breastfeeding must continue while taking the medication, close monitoring of the infant is essential. Alternative diabetes medications with better safety profiles during lactation should be considered whenever possible.

• Alcohol

Alcohol consumption should be limited or avoided while taking Damita M 10/500 Tablet, as excessive alcohol consumption can alter glycemic control and increase the risk of side effects. Alcohol can increase the risk of lactic acidosis, particularly due to the metformin component. It can also cause unpredictable changes in blood sugar levels, leading to either hypoglycemia or hyperglycemia. Patients who consume alcohol should monitor blood sugar levels more frequently and be aware of symptoms of lactic acidosis. If alcohol consumption is unavoidable, it should be done in moderation and with food. Healthcare providers should be informed about alcohol consumption patterns to adjust treatment accordingly.

• Using Machinery & Driving

Damita M 10/500 Tablet may affect the ability to drive or operate machinery, particularly during initial treatment or dose adjustments. The risk of hypoglycemia, especially when combined with other diabetes medications, can cause dizziness, confusion, or weakness that impairs judgment and reaction time. Patients should be cautious when driving until they understand how the medication affects them individually. Blood sugar should be well-controlled before engaging in activities requiring alertness and coordination. If experiencing symptoms of low blood sugar, patients should stop driving immediately and treat the hypoglycemia. Regular blood sugar monitoring before driving is recommended, particularly for patients on multiple diabetes medications.

• Food Interactions

Damita M 10/500 Tablet can be taken with or without food, as food does not significantly affect its absorption. However, taking the medication with meals may help reduce gastrointestinal side effects associated with metformin. Patients should maintain consistent dietary habits and follow their prescribed diabetic diet plan. High-fiber foods may slow the absorption of metformin but do not significantly impact its effectiveness. Avoiding excessive simple carbohydrates helps optimize the medication's glucose-lowering effects. Adequate hydration is important, especially since SGLT2 inhibitors increase urination. Patients should discuss any significant dietary changes with their healthcare provider to ensure optimal medication effectiveness.

• Drug Interactions

Several important drug interactions exist with Damita M 10/500 Tablet. When combined with insulin or sulfonylureas like gliclazide, the risk of hypoglycemia increases significantly. Diuretics may increase the risk of dehydration and kidney problems. Contrast agents used in imaging studies can cause acute renal failure, requiring temporary discontinuation of the medication 48 hours before and after the procedure. Blood pressure medications may require monitoring as SGLT2 inhibitors can cause modest blood pressure reduction. Certain antibiotics and antifungal medications may interact with metformin. Patients should inform all healthcare providers about this medication before starting any new treatments. Over-the-counter medications and supplements should also be discussed with healthcare providers.

Storage Instructions:

Store below 30°C.

Keep out of reach of children.

Keep the medication in its original container with the lid tightly closed to protect from humidity. Keep the medication away from children. Do not use tablets that appear damaged, discolored, or past their expiration date.

Other Notes:

Regular follow-up appointments with healthcare providers are essential while taking Damita M 10/500 Tablet. Blood tests to monitor kidney function, blood sugar levels, and overall health should be performed as recommended by your healthcare provider. Patients should maintain a blood sugar diary to track patterns and medication effectiveness. Emergency medical identification should be carried, indicating diabetes and current medications. Foot care becomes crucial as diabetes can affect circulation and healing. Patients should report any signs of infection, particularly urinary tract or genital infections, promptly. Maintaining recommended vaccinations, particularly flu and pneumonia vaccines, is important for diabetic patients. Stress management and regular sleep patterns can also impact blood sugar control.

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Frequently Asked Questions (FAQ)

Q: How long does it take for Damita M 10/500 Tablet to show effects?

A: Most patients begin to see blood sugar improvements within 1-2 weeks of starting treatment, with maximum effects typically achieved after 8-12 weeks of consistent use. Regular blood sugar monitoring will help track your progress and allow your doctor to make necessary adjustments to optimize your treatment plan.

Q: Can I stop taking Damita M 10/500 Tablet if my blood sugar levels normalize?

A: No, you should never stop taking Damita M 10/500 Tablet without consulting your healthcare provider, even if your blood sugar levels improve significantly. Diabetes is a chronic condition requiring ongoing management, and stopping medication abruptly can cause dangerous spikes in blood sugar levels that may lead to serious complications.

Q: What should I do if I experience frequent urination after starting this medication?

A: Increased urination is a common and expected effect of dapagliflozin, as it works by removing excess glucose through urine, but if it becomes severe or is accompanied by signs of dehydration, dizziness, or persistent thirst, contact your healthcare provider. Staying adequately hydrated and monitoring for signs of urinary tract infections is important during treatment.

Q: Is it safe to take Damita M 10/500 Tablet with my blood pressure medications?

A: Many patients safely take Damita M 10/500 Tablet with blood pressure medications, but close monitoring is necessary as the combination may enhance blood pressure-lowering effects and require dose adjustments. Always inform all your healthcare providers about every medication you're taking, including over-the-counter drugs and supplements, to prevent potentially dangerous interactions.

Q: What are the warning signs that I should seek immediate medical attention while taking this medication?

A: Seek immediate medical help if you experience symptoms of lactic acidosis (unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or slow heart rate), severe dehydration, signs of diabetic ketoacidosis (nausea, vomiting, stomach pain, confusion, unusual drowsiness), or severe hypoglycemia (extreme weakness, confusion, trembling, or loss of consciousness). These conditions require emergency treatment and can be life-threatening if left untreated.