Azifine+ 500 mg Tablet (5 Tab)

Azifine+ 500 Tablet Overview:

Azifine+ 500 Tablet is a broad-spectrum macrolide antibiotic prescribed to treat mild to moderate infections caused by certain bacteria and other microorganisms. It effectively treats infections in various body parts, including the ears, lungs, sinuses, throat, skin, and reproductive organs. It is also used to treat certain sexually transmitted infections. Azifine+ 500 Tablet works by either killing the bacteria or stopping their growth.

Composition of Azifine+ 500 Tablet:

Each film coated Azifine+ 500 Tablet contains: Azithromycin (as dehydrate) equivalent to Azithromycin Anhydrous 500 mg and Excipients q.s.

Colours: Titanium Dioxide IP.

Uses and Benefits of Azifine+ 500 Tablet:

Azifine+ 500 Tablet is commonly prescribed for treating a wide range of bacterial infections, including:

• Respiratory tract infections such as bronchitis, pneumonia, sinusitis, tonsillitis, and pharyngitis, affecting the chest, throat, or nasal passages.

• Ear infections, specifically middle ear infections (otitis media).

• Skin and soft tissue infections, excluding burn infections.

• Sexually transmitted infections (STIs) like chlamydia and gonorrhea.

• Urogenital infections, including infections of the urethra and cervix.

Additionally, Azifine+ 500 Tablet is used to treat or prevent Mycobacterium avium Complex (MAC) infections, a type of lung infection that commonly occurs in individuals with HIV.

How Azifine+ 500 Tablet works:

Azifine+ 500 Tablet contains azithromycin, a macrolide antibiotic used to treat bacterial infections. It works by blocking the production of proteins essential for bacterial growth and survival. This prevents bacteria from multiplying, helping the immune system eliminate the infection. Azithromycin is mainly bacteriostatic, meaning it stops bacterial growth, but at higher doses, it can be bactericidal, directly killing the bacteria.

Dosage of Azifine+ 500 Tablet:

• Usage Direction

Take Azifine+ 500 Tablet exactly as prescribed by your doctor, and follow the recommended dosage and schedule. Azifine+ 500 Tablet should be swallowed as a whole without crushing, chewing, or breaking it, and ideally at the same time each day. Do not stop or alter the dose of Azifine+ 500 Tablet without consulting your doctor, as this may prevent you from achieving the desired outcome. Ask your doctor or pharmacist to explain any administration procedures you do not understand.

• Missed Dose

If you miss a dose of Azifine+ 500 Tablet, take it as soon as it is remembered. If it is time for your next dose of Azifine+ 500 Tablet, skip the missed dose and resume your regular schedule. Avoid taking double doses of Azifine+ 500 Tablet to make up for the missed one.

• Over Dose

If you accidentally take Azifine+ 500 Tablet more than your prescribed dose, seek immediate medical advice, as this may lead to serious side effects.

Contraindications of Azifine+ 500 Tablet:

Do not take Azifine+ 500 Tablet if you are allergic or hypersensitive to azithromycin or any of the ingredients of this medicine. This product should be avoided if you are allergic to any other macrolide or ketolide antibiotic such as clarithromycin, erythromycin, roxithromycin, or telithromycin.

Precautions & Warnings of Azifine+ 500 Tablet:

Before using Azifine+ 500 Tablet, tell your doctor if you have severe liver or kidney problems, heart problems, irregular heartbeat (like long QT syndrome), low blood potassium or magnesium levels, cystic fibrosis, myasthenia gravis that causes muscle weakness, or any neurological or psychiatric disorders. Also, inform your doctor if you experience diarrhea or loose stools during or after treatment with Azifine+ 500 Tablet.

Side Effects of Azifine+ 500 Tablet:

Azifine+ 500 Tablet may cause some side effects, most of which are mild and usually go away as your body adjusts to the medication. If any of these symptoms persist or worry you, it is important to consult your doctor. These side effects may include nausea, dizziness, headache, diarrhea, fatigue, skin rash, constipation, and thrush in the mouth or vagina. However, some side effects may be more serious and require immediate medical attention, such as irregular heartbeat, fainting, fever, hives, severe or bloody diarrhoea, dark urine, hearing problems or ringing in the ears, dizziness, and pancreatitis. To manage these symptoms, some simple strategies such as staying well hydrated, eating light and balanced meals and getting proper rest can be beneficial.

Safety Related Concerns of Azifine+ 500 Tablet:

• Pregnancy

If you are pregnant or planning to become pregnant, talk to your doctor to determine if Azifine+ 500 Tablet is safe for you, as it may affect your developing baby during pregnancy.

• Breastfeeding

Breastfeeding mothers are advised to avoid Azifine+ 500 Tablet as it may pass through breast milk and can cause side effects in breastfed babies. Therefore, it is important to consult your doctor before taking Azifine+ 500 Tablet while breastfeeding.

• Alcohol

Although no direct interaction between Azifine+ 500 Tablet and alcohol has been found, it is advisable to limit or avoid alcohol consumption. This helps reduce the risk of potential side effects and ensures Azifine+ 500 Tablet works effectively without interference.

• Food or Interactions with Other Medicines

It is advisable to avoid any foods that you may be allergic to while taking Azifine+ 500 Tablet. Additionally, inform your doctor if you are using any herbal products, dietary supplements, antacids or other medications, as they may interact with the Azifine+ 500 Tablet. Always follow your healthcare provider’s guidance regarding your diet and medication use to ensure the treatment is safe and effective.

• Driving

If you experience side effects such as dizziness or blurred vision, you should avoid driving or operating machinery while taking Azifine+ 500 Tablet.

Storage of Azifine+ 500 Tablet:

Store at a temperature not exceeding 30°C. Protect from light & moisture.

Keep Azifine+ 500 Tablet out of reach of children.

Note: Take Azifine+ 500 Tablet at least 1 to 2 hours before eating; staying hydrated, consuming light, balanced meals, and getting enough rest can improve your condition.

Frequently Asked Questions (FAQs) about Azifine+ 500 Tablet:

1. What are the uses of Azifine+ 500 Tablet?

Azifine+ 500 Tablet is a macrolide antibiotic prescribed for the treatment of mild to moderate infections caused by bacteria. It helps fight infections in different parts of the body such as the ears, lungs, throat, sinuses, skin, and reproductive organs. It is also used to treat some sexually transmitted infections. Azifine+ 500 Tablet works by stopping the growth of bacteria or killing them, helping the body recover from the infection.

2. Can Azifine+ 500 Tablet be used for viral infections?

No, Azifine+ 500 Tablet is an antibiotic medicine and is effective only against bacterial infections, not viral infections. It works by inhibiting the growth of infection-causing bacteria. It will not work for the common cold, flu, or other viral infections. For viral infections, antiviral medications should be required. Always seek advice from a healthcare provider for the correct treatment based on the type of infection. Do not self-medicate.

3. Why is it important to complete the course of the antibiotic Azifine+ 500 Tablet?

Depending on your condition, the treatment should last 3-10 days. It is essential to complete the full course of Azifine+ 500 Tablet, even if you start to feel better, for several important reasons:

Stopping the medication in between treatments may leave some bacteria alive, and those bacteria may multiply, causing the infection to return.

Incomplete courses of Azifine+ 500 Tablet prematurely can lead to the development of bacterial-resistant infections, which are harder to treat and can spread easily.

Completing the full course of Azifine+ 500 Tablet ensures all harmful bacteria are killed, preventing stronger strains from developing.

4. How does Azifine+ 500 Tablet work to treat bacterial infections?

Azifine+ 500 Tablet has azithromycin, a macrolide antibiotic that treats bacterial infections. It works by stopping bacteria from making the proteins they need to grow and survive. This helps stop the infection from spreading and allows the immune system to clear it. Azithromycin usually stops bacteria from growing (bacteriostatic), but in higher doses, it can kill the bacteria directly (bactericidal).

5. Is Azifine+ 500 Tablet safe to use during pregnancy?

Azifine+ 500 Tablet is usually considered safe for use during pregnancy when prescribed by a doctor. The FDA classifies it as a Category B medication, indicating that animal studies have not shown harm to the fetus, although there are limited studies involving pregnant women. It is important to consult your doctor before using any medication during pregnancy to ensure it is suitable for your specific situation.

6. Can I take Azifine+ 500 Tablet together with other medications?

Before taking Azifine+ 500 Tablet, it is important to consult your doctor if you are taking other medications, such as antacids containing aluminium hydroxide or magnesium hydroxide, cholesterol-lowering medicine (e.g., Statins), blood thinners (e.g., Warfarin), etc. Be sure to inform your doctor about all the medications you are taking to ensure safety and avoid potential interactions.

7. What is the recommended daily dosage for Azifine+ 500 Tablet?

The dose of Azifine+ 500 Tablet depends on how serious your infection is and should be taken exactly as your doctor prescribes. Always follow your doctor’s directions to make sure the medicine works properly to treat your infection.

References:

1. Patient Information. ZITHROMAX. (azithromycin) Tablets. ZITHROMAX (azithromycin) Oral Suspension. Last Revised: July, 2016. Accessed on: 12.05.2025. Click Here

2. Azithromycin. NHS. Last Revised: 20 January 2022. Accessed on: 12.05.2025. Click Here

3. Azithromycin. MedlinePlus. Last Revised: 15 January 2024. Accessed on: 12.05.2025. Click Here

4. Package leaflet: Information for the user. Azithromycin 250 mg film-coated tablets Azithromycin 500 mg film-coated tablets. Last Revised: January 2025. Accessed on: 12.05.2025. Click Here

5. Azithromycin Sandoz. azithromycin dehydrate. Consumer Medicine Information. Last Revised: October 2024. Accessed on: 12.05.2025. Click Here