Augpen I.V. 1.2 gm Injection

Augpen 1.2 g Injection Overview:

Augpen 1.2 g Injection is a combination antibiotic medication used for the short-term treatment of various bacterial infections. It is effective against infections in areas like the ears, lungs, sinuses, urinary tract, skin, and soft tissues, including dental, bones, and joints. Augpen 1.2 g Injection works by targeting and eliminating the bacteria responsible for these infections.

Composition of Augpen 1.2 g Injection:

Each Vial Contains: Amoxycillin Sodium (Sterile) equivalent to Amoxycillin 1000 mg , Potassium Clavulanate (Sterile) equivalent to Clavulanic Acid 200 mg

Uses and Benefits of Augpen 1.2 g Injection:

Augpen 1.2 g Injection is used to treat a wide range of bacterial infections following:

• Upper respiratory tract infections- Middle ear and sinus infections and inflammation of tonsils
• Lower respiratory tract infections- Chronic obstructive pulmonary disease (COPD), pneumonia
• Urinary tract infections (UTIs)- Infection of bladder and kidney as well as inflammation of urethra
• Skin and soft tissue infections- Infections caused by cuts, bites, or other wounds, also dental abscesses
• Bone and joint infections- Osteomyelitis
• Intra-abdominal Infections- Appendicitis, inflammation of the peritoneum.
• Other Infections- Uterine infection during or after abortion, miscarriage or childbirth.

 How Augpen 1.2 g Injection Works:

Augpen 1.2 g Injection contains two active ingredients, Amoxicillin and Clavulanic acid, that work together as a combination antibiotic to treat bacterial infections.

Amoxicillin is an antibiotic medicine, belongs to the  that stops the growth of infections causing bacteria by preventing them from forming their protective outer layer. While Clavulanic acid belongs to the class of medicines called ‘beta-lactamase inhibitors’ that helps amoxicillin work better. It works by blocking an enzyme called beta-lactamase, which some bacteria produce to protect themselves. Beta-lactamase can break down amoxicillin, making it ineffective, thereby allowing amoxicillin to work properly.

Dosage of Augpen 1.2 g Injection:

• Usage Direction

Augpen 1.2 g Injection is intended for intravenous use only and must be administered by a healthcare professional. Withdraw 10 ml of sterile water for injection and use to dissolve the contents. Shake well. Do not attempt to self-administer this medication. Your doctor will determine the appropriate dosage based on your medical condition and how you respond to treatment. Do not stop or alter the dose of Augpen 1.2 g Injection without consulting your doctor, as this may prevent you from achieving the desired result.Use immediately after reconstitution.

• Missed Dose

If you miss a dose of Augpen 1.2 g Injection, take it as soon as it is remembered. If it is time for your next dose of Augpen 1.2 g Injection, skip the missed dose and resume your regular schedule. Avoid taking two doses to compensate for a missed one.

• Over Dose

If you accidentally take Augpen 1.2 g Injection more than your prescribed dose, seek immediate medical advice, as this may lead to serious side effects.

Contraindications of Augpen 1.2 g Injection:

Do not take Augpen 1.2 g Injection  if you are allergic to Amoxicillin, Clavulanic acid, other penicillins or cephalosporins, or any other ingredients of this medicine. Augpen 1.2 g Injection should be avoided if you have ever had liver problems or jaundice when taking an antibiotic.

Precautions & Warnings of Augpen 1.2 g Injection:

Before starting Augpen 1.2 g Injection, inform your doctor if you have glandular fever (mononucleosis), Clostridium difficile associated diarrhea (CDAD), skin rash in patients with mononucleosis, or are being treated for liver or kidney problems.

Side Effects of Augpen 1.2 g Injection:

Augpen 1.2 g Injection may cause some side effects, most of which do not require medical attention and typically go away as your body adjusts to the medication. However, if these effects persist, consult your doctor. These may include; diarrhea, upset stomach, vomiting, vaginal itching and/or discharge. To help manage these, drink plenty of water, avoid foods that may cause gas, eat fiber-rich foods, and rest if you experience lightheadedness. Some severe side effects may also occur which need medical attention such as liver inflammation, black hairy tongue, dark urine or pale stools, severe stomach cramps, severe watery or bloody diarrhoea.

Safety Related Concerns of Augpen 1.2 g Injection:

• Pregnancy

Augpen 1.2 g Injection is generally safe during pregnancy. If you are pregnant or planning to become pregnant, consult your doctor to determine if Augpen 1.2 g Injection is safe for you to take.

• Breastfeeding

Augpen 1.2 g Injection may pass into breast milk in small amounts, which is unlikely to cause significant side effects in most breastfeeding infants. However, some babies may experience symptoms like rash or diarrhea. If you notice any of these issues, it's important to contact your doctor. Therefore, it is important to consult your doctor before taking Augpen 1.2 g Injection while breastfeeding.

• Alcohol

Although no direct interaction between Augpen 1.2 g and alcohol has been found, but it is recommended to limit alcohol intake to avoid potential side effects.

• Food or Interactions with Other Medicines

Avoid dairy based and calcium riched foods such as milk, cheese, yogurt or butter as well as citrus fruits like orange and grapefruit while taking Augpen 1.2 g Injection.

Consult your doctor if you are taking any herbal products or supplements while taking Augpen 1.2 g Injection. As always, it is a good idea to consult your doctor or healthcare provider about your specific dietary needs while on Augpen 1.2 g Injection.

• Driving

If you experience side effects such as dizziness or blurred vision, you should avoid driving or operating machinery while taking Augpen 1.2 g Injection.

Caution: After reconstitution, do not use in case any foreign particulate matter is observed inside the vial.

Storage Instructions of Augpen 1.2 g Injection:

Store below 25°C. Protected from moisture. Do not freeze.

Keep all medicines out of reach of children.

Note: Consume healthy, easily digestible food and stay hydrated to help improve your condition.

Frequently Asked Questions (FAQs) about Augpen 1.2 g Injection:

1. What are the uses of Augpen 1.2 g Injection?

Augpen 1.2 g is an antibiotic used to treat various bacterial infections. It helps with respiratory issues like pneumonia, bronchitis, and sinus infections, as well as urinary tract infections, ear infections, and skin infections. It can also be used for bone and joint infections, stomach infections, and to prevent infections in patients with weakened immune systems or before surgery. Additionally, it treats heart valve infections (endocarditis) and gallbladder infections (cholecystitis).

2. Can Augpen 1.2 g Injection be used for viral infections?

No, Augpen 1.2 g Injection is an antibiotic medicine and is effective only against bacterial infections, not viral infections. It works by inhibiting the growth of infections-causing bacteria. It will not work for the common cold, flu, or other viral infections. For viral infections, antiviral medications may be required. Always seek advice from a healthcare provider for the correct treatment based on the type of infection. Do not self-medicate.

3. How does Augpen 1.2 g Injection work to treat bacterial infections?

Augpen 1.2 g Injection contains Amoxicillin and Clavulanic acid as its active ingredients to treat bacterial infections. Amoxicillin, a penicillin-type antibiotic, works by preventing bacteria from forming their protective outer layer, stopping their growth. On the other hand, Clavulanic acid, a beta-lactamase inhibitor, enhances amoxicillin’s effectiveness by blocking the beta-lactamase enzyme that some bacteria produce to protect themselves.

4. Is Augpen 1.2 g Injection  safe to use during pregnancy?

Augpen 1.2 g Injection is usually considered as safe for use during pregnancy when prescribed by a doctor. The FDA classifies it as a Category B medication, indicating that animal studies have not shown harm to the fetus, although there are limited studies involving pregnant women. It’s important to consult your doctor before using any medication during pregnancy to ensure it is suitable for your specific situation.

5. Why it is important to complete the course of Augpen 1.2 g Injection ?

Depending on your condition, the treatment should last 7-14 days. It is essential to complete the full course of Augpen 1.2 g Injection, even if you start to feel better, for several important reasons:

Stopping the medication in between treatments may leave some bacteria alive, and those bacteria may multiply, causing the infection to return.

Incomplete courses of antibiotics ( Augpen 1.2 g Injection )can lead to bacteria becoming resistant, which are difficult to treat and can spread.

Completing the full course of Augpen 1.2 g Injection ensures all harmful bacteria are killed, preventing stronger strains from developing.

6. How many times a day I should take Augpen 1.2 g Injection?

7. The exact dose of Augpen 1.2 g Injection will depend on the severity of your infection, as prescribed by your doctor. Always follow your doctor's instructions regarding the dosage and frequency. This ensures the medication is effective in treating your infection.

7. Can I take Augpen 1.2 g Injection together with other medications?

Before taking Augpen 1.2 g Injection, it is important to consult your doctor if you are taking other medications, such as blood thinners (e.g., Warfarin), or antacids. In some cases, it can make birth control pills less effective. So informing your doctor about any other drugs you're taking is crucial.

Reference:

1. AUGMENTIN BD TABLETS. Amoxicillin trihydrate - Potassium clavulanate. Last Revised: January 18, 2013. Accessed on: 24.03.2025. Click Here

2. Mother To Baby | Fact Sheets [Internet]. Brentwood (TN): Organization of Teratology Information Specialists (OTIS); 1994-. Amoxicillin and Clavulanic acid. 2024 Mar. Click Here

Langford, B. J., & Morris, A. M. (2017). Is it time to stop counselling patients to "finish the course of antibiotics"?. Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC, 150(6), 349–350. Accessed on: 24.03.2025. Click Here