Amoxyclav 375 mg Tablet (10 Tab)

Amoxyclav 375 Tablet Overview:

Amoxyclav 375 Tablet is a combination antibiotic medication used for the short-term treatment of various bacterial infections. It is effective against infections in areas like the ears, lungs, sinuses, urinary tract, skin, and soft tissues, including dental, bones, and joints. Amoxyclav 375 Tablet works by targeting and eliminating the bacteria responsible for these infections.

Composition of Amoxyclav 375 Tablet:

Each film coated Amoxyclav 375 Tablet contains- Amoxicillin Trihydrate equivalent to Amoxycillin 250 mg and Potassium Clavulanate Diluted equivalent to Clavulanic Acid 125 mg.

Colour: Titanium Dioxide.

Uses and Benefits of Amoxyclav 375 Tablet:

Amoxyclav 375 Tablet is used to treat a wide range of bacterial infections following:

• Upper respiratory tract infections- Middle ear and sinus infections and inflammation of tonsils
• Lower respiratory tract infections- Chronic obstructive pulmonary disease (COPD), pneumonia
• Urinary tract infections (UTIs)- Infection of bladder and kidney as well as inflammation of urethra
• Skin and soft tissue infections- Infections caused by cuts, bites, or other wounds, also dental abscesses
• Bone and joint infections- Osteomyelitis
• Intra-abdominal Infections- Appendicitis, inflammation of the peritoneum.
• Other Infections- Uterine infection during or after abortion, miscarriage or childbirth.

 How Amoxyclav 375 Tablet Works:

Amoxyclav 375 Tablet contains two active ingredients, Amoxicillin and Clavulanic acid, that work together as a combination antibiotic to treat bacterial infections.

Amoxicillin is an antibiotic medicine, belongs to the  that stops the growth of infections causing bacteria by preventing them from forming their protective outer layer. While Clavulanic acid belongs to the class of medicines called ‘beta-lactamase inhibitors’ that helps amoxicillin work better. It works by blocking an enzyme called beta-lactamase, which some bacteria produce to protect themselves. Beta-lactamase can break down amoxicillin, making it ineffective, thereby allowing amoxicillin to work properly.

Dosage of Amoxyclav 375 Tablet:

• Usage Direction

Take Amoxyclav 375 Tablet exactly as prescribed by your doctor, and follow the recommended dosage and schedule. Amoxyclav 375 Tablet should be swallowed as whole without crushing, chewing, or breaking it, and ideally at the same time each day. Do not stop or alter the dose of Amoxyclav 375 Tablet without consulting your doctor, as this may prevent you from achieving the desired result. Ask your doctor or pharmacist to explain any administration procedures you do not understand.

• Missed Dose

If you miss a dose of Amoxyclav 375 Tablet, take it as soon as it is remembered. If it is time for your next dose of Amoxyclav 375 Tablet, skip the missed dose and resume your regular schedule. Avoid taking two doses to compensate for a missed one.

• Over Dose

If you accidentally take Amoxyclav 375 Tablet more than your prescribed dose, seek immediate medical advice, as this may lead to serious side effects.

• Contraindications of Amoxyclav 375 Tablet:

Do not take Amoxyclav 375 Tablet if you are allergic to Amoxicillin, Clavulanic acid, other penicillins or cephalosporins, or any other ingredients of this medicine. Amoxyclav 375 Tablet should be avoided if you have ever had liver problems or jaundice when taking an antibiotic.

Precautions & Warnings of Amoxyclav 375 Tablet:

Before starting Amoxyclav 375 Tablet, inform your doctor if you have glandular fever (mononucleosis), Clostridium difficile associated diarrhea (CDAD), skin rash in patients with mononucleosis, or are being treated for liver or kidney problems.

Side Effects of Amoxyclav 375 Tablet:

Amoxyclav 375 Tablet may cause some side effects, most of which do not require medical attention and typically go away as your body adjusts to the medication. However, if these effects persist, consult your doctor. These may include; diarrhea, upset stomach, vomiting, vaginal itching and/or discharge. To help manage these, drink plenty of water, avoid foods that may cause gas, eat fiber-rich foods, and rest if you experience lightheadedness. Some severe side effects may also occur which need medical attention such as liver inflammation, black hairy tongue, dark urine or pale stools, severe stomach cramps, severe watery or bloody diarrhoea.

Safety Related Concerns of Amoxyclav 375 Tablet:

• Pregnancy

Amoxyclav 375 Tablet is generally safe during pregnancy. If you are pregnant or planning to become pregnant, consult your doctor to determine if Amoxyclav 375 Tablet is safe for you to take.

• Breastfeeding

Amoxyclav 375 Tablet may pass into breast milk in small amounts, which is unlikely to cause significant side effects in most breastfeeding infants. However, some babies may experience symptoms like rash or diarrhea. If you notice any of these issues, it's important to contact your doctor. Therefore, it is important to consult your doctor before taking Amoxyclav 375 Tablet while breastfeeding.

• Alcohol

Although no direct interaction between Amoxyclav 375 and alcohol has been found, but it is recommended to limit alcohol intake to avoid potential side effects.

• Food or Interactions with Other Medicines

Avoid dairy based and calcium riched foods such as milk, cheese, yogurt or butter as well as citrus fruits like orange and grapefruit while taking Amoxyclav 375 Tablet.

Consult your doctor if you are taking any herbal products or supplements while taking Amoxyclav 375 Tablet. As always, it is a good idea to consult your doctor or healthcare provider about your specific dietary needs while on Amoxyclav 375 Tablet.

• Driving

If you experience side effects such as dizziness or blurred vision, you should avoid driving or operating machinery while taking Amoxyclav 375 Tablet.

Storage Instructions of Amoxyclav 375 Tablet:

Store protected from moisture, at a temperature not exceeding 25ºC.

Keep out of reach of children.

Note: Consume healthy, easily digestible food and stay hydrated to help improve your condition.

Frequently Asked Questions (FAQs) about Amoxyclav 375 Tablet:

1. What are the uses of Amoxyclav 375 Tablet?

Amoxyclav 375 is an antibiotic used to treat various bacterial infections. It helps with respiratory issues like pneumonia, bronchitis, and sinus infections, as well as urinary tract infections, ear infections, and skin infections. It can also be used for bone and joint infections, stomach infections, and to prevent infections in patients with weakened immune systems or before surgery. Additionally, it treats heart valve infections (endocarditis) and gallbladder infections (cholecystitis).

2. Can Amoxyclav 375 Tablet be used for viral infections?

No, Amoxyclav 375 is an antibiotic medicine and is effective only against bacterial infections, not viral infections. It works by inhibiting the growth of infections-causing bacteria. It will not work for the common cold, flu, or other viral infections. For viral infections, antiviral medications may be required. Always seek advice from a healthcare provider for the correct treatment based on the type of infection. Do not self-medicate.

3. How does Amoxyclav 375 Tablet work to treat bacterial infections?

Amoxyclav 375 Tablet contains Amoxicillin and Clavulanic acid as its active ingredients to treat bacterial infections. Amoxicillin, a penicillin-type antibiotic, works by preventing bacteria from forming their protective outer layer, stopping their growth. On the other hand, Clavulanic acid, a beta-lactamase inhibitor, enhances amoxicillin’s effectiveness by blocking the beta-lactamase enzyme that some bacteria produce to protect themselves.

4. Is Amoxyclav 375 Tablet safe to use during pregnancy?

Amoxyclav 375 Tablet is usually considered as safe for use during pregnancy when prescribed by a doctor. The FDA classifies it as a Category B medication, indicating that animal studies have not shown harm to the fetus, although there are limited studies involving pregnant women. It’s important to consult your doctor before using any medication during pregnancy to ensure it is suitable for your specific situation.

5. Why it is important to complete the course of Amoxyclav 375 Tablet?

Depending on your condition, the treatment should last 7-14 days. It is essential to complete the full course of Amoxyclav 375 Tablet, even if you start to feel better, for several important reasons:

Stopping the medication in between treatments may leave some bacteria alive, and those bacteria may multiply, causing the infection to return.

Incomplete courses of antibiotics (Amoxyclav 375 Tablet) can lead to bacteria becoming resistant, which are difficult to treat and can spread.

Completing the full course of Amoxyclav 375 Tablet ensures all harmful bacteria are killed, preventing stronger strains from developing.

6. How many times a day I should take Amoxyclav 375 Tablet?

The exact dose of Amoxyclav 375 Tablet will depend on the severity of your infection, as prescribed by your doctor. Typically, it is taken every 8 hours (3 times a day) or every 12 hours (2 times a day). Always follow your doctor's instructions regarding the dosage and frequency. This ensures the medication is effective in treating your infection.

7. Can I take Amoxyclav 375 Tablet together with other medications?

Before taking Amoxyclav 375 Tablet, it is important to consult your doctor if you are taking other medications, such as blood thinners (e.g., Warfarin), or antacids. In some cases, it can make birth control pills less effective. So informing your doctor about any other drugs you're taking is crucial.

Reference:

1. AUGMENTIN BD TABLETS. Amoxicillin trihydrate - Potassium clavulanate. Last Revised: January 18, 2013. Accessed on: 24.03.2025. Click Here

2. Mother To Baby | Fact Sheets [Internet]. Brentwood (TN): Organization of Teratology Information Specialists (OTIS); 1994-. Amoxicillin and Clavulanic acid. 2024 Mar. Click Here