Advastat F Tablet (10 Tab)

Advastat F Tablet Overview:

Advastat F Tablet is a medication designed specifically to help manage high levels of fats in the blood, such as cholesterol and triglycerides. This tablet combines two active ingredients to target lipid imbalances effectively, making it a popular choice for those dealing with conditions like hyperlipidemia or mixed dyslipidemia. By lowering bad cholesterol (LDL) and triglycerides while boosting good cholesterol (HDL), it plays a key role in reducing the risk of serious heart-related issues, including heart attacks and strokes. It's especially useful when lifestyle changes alone, like diet and exercise, aren't enough to control these levels. Research from studies on rosuvastatin-fenofibrate combinations highlights its efficacy in improving lipid profiles in patients with mixed dyslipidemia, showing significant reductions in triglycerides and LDL without major safety concerns in controlled trials.

Composition:

Each film coated tablet contains- Rosuvastatin Calcium equivalent to Rosuvastatin: 10 mg, Fenofibrate: 160 mg and Excipients q.s.

Colours: Lake Quinoline Yellow & Titanium Dioxide.

Uses & Benefits of Advastat F Tablet:

Advastat F Tablet offers several benefits for individuals struggling with elevated lipid levels. It effectively lowers harmful fats in the blood, which helps prevent the buildup of plaque in arteries, reducing the chances of cardiovascular events like heart attacks or strokes. Patients may experience improved overall heart health, better energy levels due to reduced strain on the circulatory system, and a lower risk of complications associated with high triglycerides, such as pancreatitis. When combined with a healthy lifestyle, it provides more comprehensive control over cholesterol than single-drug therapies, as supported by research studies showing enhanced efficacy in lipid reduction with rosuvastatin-fenofibrate combinations. Additionally, it can aid in managing diabetic dyslipidemia, helping those with diabetes maintain better blood sugar and lipid balance. Overall, this tablet supports long-term wellness by promoting healthier blood vessels and a stronger heart.

How Advastat F Tablet Works:

Advastat F Tablet operates through the combined actions of its ingredients: rosuvastatin inhibits an enzyme called HMG-CoA reductase in the liver, which slows down the production of cholesterol, leading to lower levels of bad cholesterol (LDL) and triglycerides in the bloodstream. Fenofibrate, on the other hand, activates certain receptors that increase the breakdown of fats and enhance the removal of triglycerides from the blood, while also raising good cholesterol (HDL). This dual mechanism ensures a more thorough approach to lipid regulation compared to using either drug alone. Prescribing information notes that this process improves the body's natural ability to handle fats, preventing their accumulation in arteries.

Dosage of Advastat F Tablet:

• Usage Directions

Always follow your doctor's guidance on dosage and timing. Swallowed whole with a glass of water, and it can be consumed with or without food, though taking it at a fixed time each day helps maintain consistent blood levels. The dose may vary based on your lipid levels, age, and response to treatment, so regular blood tests are advised to monitor progress. Prescribing leaflets emphasize combining the tablet with a low-fat diet, regular exercise, and weight management for best results. Avoid crushing or chewing the tablet, as this could affect its release and effectiveness.

• Missed Dose

If you forget a dose of Advastat F Tablet, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed one and resume your regular routine to prevent doubling up, which could lead to unwanted effects. Setting reminders or linking the dose to a daily habit can help avoid misses. Prescribing information advises not to compensate by taking extra tablets, as consistency is more important than perfection. If misses happen frequently, consult your doctor to adjust your plan and ensure your lipid control remains on track.

• Overdose

Seek immediate medical attention in case of overdose, as it can lead to intensified side effects like severe muscle pain or liver issues. Symptoms might include excessive nausea, dizziness, or weakness, and it's crucial to inform healthcare providers about the amount taken and when. Prescribing leaflets recommend contacting a poison control center or emergency room right away. To prevent overdose, stick strictly to the prescribed dose and store the medication out of reach of children. Research on the combination drugs suggests that while overdoses are rare, prompt treatment can mitigate risks effectively.

Contraindications of Advastat F Tablet:

Advastat F Tablet should not be used if you have a known allergy to rosuvastatin, fenofibrate, or any tablet components, as this could cause severe reactions. It's also contraindicated in cases of severe liver or kidney disease, active gallbladder issues like stones or inflammation, or unexplained persistent muscle pain. Patients with a history of pancreatitis or those taking certain immunosuppressants like cyclosporine should avoid it. Prescribing information stresses avoiding it during pregnancy or breastfeeding due to potential harm. Always discuss your medical history with your doctor to confirm it's safe for you.

Precautions & Warnings of Advastat F Tablet:

It is essential to monitor liver and kidney function regularly through blood tests, as the medication can affect these organs. Diabetic patients should watch their blood sugar levels, as it might cause slight increases. Elderly individuals or those with thyroid issues may need dose adjustments. Prescribing leaflets warn against sudden stops, as this could raise lipid levels and heart risks. Lifestyle precautions include quitting smoking and limiting alcohol.

Statin Warning: Patients should notify to their healthcare professional immediately if they following symptoms; liver problems, unusual fatigue or weakness, loss of appetite, upper belly pain, dark colored urine, yellowing of skin or eyes, memory loss confusion and increase in blood sugar levels.

Side Effects of Advastat F Tablet:

Common Advastat F Tablet side effects include headache, muscle pain, constipation, nausea, abdominal discomfort, and weakness, which often resolve as your body adjusts. Less frequent issues might involve abnormal liver function tests, joint pain, or elevated blood sugar. In rare cases, severe muscle breakdown (rhabdomyolysis) or liver damage can occur, signaled by dark urine, yellowing eyes, or unexplained fatigue—seek help immediately if noticed. Prescribing information notes that most effects are mild, but inform your doctor if they persist.

Safety Related Concerns of Advastat F Tablet:

• Pregnancy

Advastat F Tablet is highly unsafe during pregnancy, as it can cause serious harm to the developing baby. Women planning pregnancy or already pregnant should avoid it and use effective contraception while on treatment. Prescribing leaflets strongly advise consulting a doctor for alternatives if conception is possible.

• Breastfeeding

It is generally not recommended during breastfeeding, as components may pass into breast milk and affect the infant. Limited data suggests potential harm, so nursing mothers should discuss safer options with their doctor. Prescribing information recommends pausing breastfeeding or switching medications.

• Alcohol

Consuming Advastat F Tablet with alcohol is unsafe, as it can heighten risks of liver damage and amplify side effects like dizziness or nausea. Prescribing leaflets advise complete avoidance of alcohol, including wine or beer, during treatment. Alcohol can interfere with lipid-lowering efficacy, making moderation crucial for heart health.

• Using Machinery & Driving

Advastat F Tablet is usually safe for "Advastat F Tablet driving" or operating machinery, as it doesn't typically impair alertness. However, if you experience dizziness or daytime drowsiness, avoid such activities until resolved.

• Food Interactions

Avoid high-fat foods, as they can counteract the tablet's benefits by raising lipid levels. A low-fat diet with fruits, vegetables, and whole grains is ideal. Prescribing leaflets suggest no specific restrictions beyond fat moderation, but grapefruit juice might interact mildly with rosuvastatin—limit intake if advised.

• Drug Interactions

Advastat F Tablet can interact with blood thinners like warfarin (increasing bleeding risk), immunosuppressants like cyclosporine (raising kidney damage chances), or other cholesterol drugs like gemfibrozil (heightening muscle issues). Antacids may reduce absorption, and antivirals like ritonavir can elevate blood levels. Always list all medications, including supplements, to your doctor.

Storage Instructions:

Store protected from light & moisture at a temperature not exceeding 30°C. Store it in its original packaging and out of reach of children. Dispose of any expired or unused pills safely, following local guidelines to avoid environmental harm.

Other Notes:

Adopting heart-healthy habits like regular exercise, weight control, and stress reduction for enhanced results. Periodic lipid profile checks are vital.

Frequently Asked Questions (FAQs):

Q. What are the main uses of Advastat F Tablet?

A. Advastat F Tablet is primarily used to lower high cholesterol and triglyceride levels in the blood, helping to prevent heart attacks and strokes when combined with diet and exercise. It provides better lipid control for conditions like hyperlipidemia.

Q. Can Advastat F Tablet cause muscle pain?

A. Yes, muscle pain is a possible side effect of Advastat F Tablet, though it doesn't affect everyone; if you experience persistent pain or weakness, especially with fever, contact your doctor promptly as it could indicate a rare muscle issue.

Q. Is Advastat F Tablet safe during pregnancy?

A. No, Advastat F Tablet is not safe during pregnancy and should be avoided, as it can harm the unborn baby; women of childbearing age should use contraception and consult their doctor for alternatives.

Q. What lifestyle changes should I make while taking Advastat F Tablet?

A. While on Advastat F Tablet, follow a low-fat diet, engage in regular physical activity, avoid smoking, and limit alcohol to maximize its benefits and support overall heart health.