Azithral 500 mg Injection

Azithral 500 mg Infusion Overview:

Azithral 500 mg Infusion is a broad-spectrum macrolide antibiotic prescribed to treat mild to moderate infections caused by certain bacteria and other microorganisms. It effectively treats infections in various body parts, including the ears, lungs, sinuses, throat, skin, and reproductive organs. It is also used to treat certain sexually transmitted infections. Azithral 500 mg Infusion works by either killing the bacteria or stopping their growth.

Composition of Azithral 500 mg Infusion:

Each vial Azithral 500 mg Infusion contains: Azithromycin (as dihydrate) equivalent to Azithromycin Anhydrous 500 mg dilute with 4.8 ml of sterile water for injection IP to make final volume of 5 ml.

Uses and Benefits of Azithral 500 mg Infusion:

Azithral 500 mg Infusion is commonly prescribed for treating a wide range of bacterial infections, including:

• Respiratory tract infections such as bronchitis, pneumonia, sinusitis, tonsillitis, and pharyngitis, affecting the chest, throat, or nasal passages.

• Ear infections, specifically middle ear infections (otitis media).

• Skin and soft tissue infections, excluding burn infections.

• Sexually transmitted infections (STIs) like chlamydia and gonorrhea.

• Urogenital infections, including infections of the urethra and cervix.

Additionally, Azithral 500 mg Infusion is used to treat or prevent Mycobacterium avium Complex (MAC) infections, a type of lung infection that commonly occurs in individuals with HIV.

How Azithral 500 mg Infusion works:

Azithral 500 mg Infusion contains azithromycin, a macrolide antibiotic used to treat bacterial infections. It works by blocking the production of proteins essential for bacterial growth and survival. This prevents bacteria from multiplying, helping the immune system eliminate the infection. Azithromycin is mainly bacteriostatic, meaning it stops bacterial growth, but at higher doses, it can be bactericidal, directly killing the bacteria.

Dosage of Azithral 500 mg Infusion:

• Usage Direction

Azithral 500 mg Infusion is intended for intravenous use only and must be administered by a healthcare professional. Do not attempt to self-administer this medication. Your doctor will determine the appropriate dosage based on your medical condition and how you respond to treatment. Do not stop or alter the dose of Azithral 500 mg Infusion without consulting your doctor, as this may prevent you from achieving the desired result.

• Missed Dose

If you miss a dose of Azithral 500 mg Infusion, take it as soon as it is remembered. If it is time for your next dose of Azithral 500 mg Infusion, skip the missed dose and resume your regular schedule. Avoid taking double doses of Azithral 500 mg Infusion to make up for the missed one.

• Over Dose

If you accidentally take Azithral 500 mg Infusion more than your prescribed dose, seek immediate medical advice, as this may lead to serious side effects.

Contraindications of Azithral 500 mg Infusion:

Do not take Azithral 500 mg Infusion if you are allergic or hypersensitive to azithromycin or any of the ingredients of this medicine. This product should be avoided if you are allergic to any other macrolide or ketolide antibiotic such as clarithromycin, erythromycin, roxithromycin, or telithromycin.

Precautions & Warnings of Azithral 500 mg Infusion:

Before using Azithral 500 mg Infusion, tell your doctor if you have severe liver or kidney problems, heart problems, irregular heartbeat (like long QT syndrome), low blood potassium or magnesium levels, cystic fibrosis, myasthenia gravis that causes muscle weakness, or any neurological or psychiatric disorders. Also, inform your doctor if you experience diarrhea or loose stools during or after treatment with Azithral 500 mg Infusion.

Side Effects of Azithral 500 mg Infusion:

Azithral 500 mg Infusion may cause some side effects, most of which are mild and usually go away as your body adjusts to the medication. If any of these symptoms persist or worry you, it is important to consult your doctor. These side effects may include nausea, dizziness, headache, diarrhea, fatigue, skin rash, constipation, and thrush in the mouth or vagina. However, some side effects may be more serious and require immediate medical attention, such as irregular heartbeat, fainting, fever, hives, severe or bloody diarrhoea, dark urine, hearing problems or ringing in the ears, dizziness, and pancreatitis. To manage these symptoms, some simple strategies such as staying well hydrated, eating light and balanced meals and getting proper rest can be beneficial.

Safety Related Concerns of Azithral 500 mg Infusion:

• Pregnancy

If you are pregnant or planning to become pregnant, talk to your doctor to determine if Azithral 500 mg Infusion is safe for you, as it may affect your developing baby during pregnancy.

• Breastfeeding

Breastfeeding mothers are advised to avoid Azithral 500 mg Infusion as it may pass through breast milk and can cause side effects in breastfed babies. Therefore, it is important to consult your doctor before taking Azithral 500 mg Infusion while breastfeeding.

• Alcohol

Although no direct interaction between Azithral 500 mg Infusion and alcohol has been found, it is advisable to limit or avoid alcohol consumption. This helps reduce the risk of potential side effects and ensures Azithral 500 mg Infusion works effectively without interference.

• Food or Interactions with Other Medicines

It is advisable to avoid any foods that you may be allergic to while taking Azithral 500 mg Infusion. Additionally, inform your doctor if you are using any herbal products, dietary supplements, antacids or other medications, as they may interact with the Azithral 500 mg Infusion. Always follow your healthcare provider’s guidance regarding your diet and medication use to ensure the treatment is safe and effective.

• Driving

If you experience side effects such as dizziness or blurred vision, you should avoid driving or operating machinery while taking Azithral 500 mg Infusion.

Storage of Azithral 500 mg Infusion:

Store protected from light and moisture at a temperature not exceeding 30°C.

Keep Azithral 500 mg Infusion out of reach of children.

Note: The reconstitute solution should be used within 24 hours of preparation.

Frequently Asked Questions (FAQs) about Azithral 500 mg Infusion:

1. What are the uses of Azithral 500 mg Infusion?

Azithral 500 mg Infusion is a macrolide antibiotic prescribed for the treatment of mild to moderate infections caused by bacteria. It helps fight infections in different parts of the body such as the ears, lungs, throat, sinuses, skin, and reproductive organs. It is also used to treat some sexually transmitted infections. Azithral 500 mg Infusion works by stopping the growth of bacteria or killing them, helping the body recover from the infection.

2. Can Azithral 500 mg Infusion be used for viral infections?

No, Azithral 500 mg Infusion is an antibiotic medicine and is effective only against bacterial infections, not viral infections. It works by inhibiting the growth of infection-causing bacteria. It will not work for the common cold, flu, or other viral infections. For viral infections, antiviral medications should be required. Always seek advice from a healthcare provider for the correct treatment based on the type of infection. Do not self-medicate.

3. Why is it important to complete the course of the antibiotic Azithral 500 mg Infusion?

Depending on your condition, the treatment should last 3-10 days. It is essential to complete the full course of Azithral 500 mg Infusion, even if you start to feel better, for several important reasons:

Stopping the medication in between treatments may leave some bacteria alive, and those bacteria may multiply, causing the infection to return.

Incomplete courses of Azithral 500 mg Infusion prematurely can lead to the development of bacterial-resistant infections, which are harder to treat and can spread easily.

Completing the full course of Azithral 500 mg Infusion ensures all harmful bacteria are killed, preventing stronger strains from developing.

4. How does Azithral 500 mg Infusion work to treat bacterial infections?

Azithral 500 mg Infusion has azithromycin, a macrolide antibiotic that treats bacterial infections. It works by stopping bacteria from making the proteins they need to grow and survive. This helps stop the infection from spreading and allows the immune system to clear it. Azithromycin usually stops bacteria from growing (bacteriostatic), but in higher doses, it can kill the bacteria directly (bactericidal).

5. Is Azithral 500 mg Infusion safe to use during pregnancy?

Azithral 500 mg Infusion is usually considered safe for use during pregnancy when prescribed by a doctor. The FDA classifies it as a Category B medication, indicating that animal studies have not shown harm to the fetus, although there are limited studies involving pregnant women. It is important to consult your doctor before using any medication during pregnancy to ensure it is suitable for your specific situation.

6. Can I take Azithral 500 mg Infusion together with other medications?

Before taking Azithral 500 mg Infusion, it is important to consult your doctor if you are taking other medications, such as antacids containing aluminium hydroxide or magnesium hydroxide, cholesterol-lowering medicine (e.g., Statins), blood thinners (e.g., Warfarin), etc. Be sure to inform your doctor about all the medications you are taking to ensure safety and avoid potential interactions.

7. What is the recommended daily dosage for Azithral 500 mg Infusion?

The dose of Azithral 500 mg Infusion depends on how serious your infection is and should be taken exactly as your doctor prescribes. Always follow your doctor’s directions to make sure the medicine works properly to treat your infection.

References:

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2. Azithromycin. NHS. Last Revised: 20 January 2022. Accessed on: 12.05.2025. Click Here

3. Azithromycin. MedlinePlus. Last Revised: 15 January 2024. Accessed on: 12.05.2025. Click Here

4. Package leaflet: Information for the user. Azithromycin 250 mg film-coated tablets Azithromycin 500 mg film-coated tablets. Last Revised: January 2025. Accessed on: 12.05.2025. Click Here

5. Azithromycin Sandoz. azithromycin dehydrate. Consumer Medicine Information. Last Revised: October 2024. Accessed on: 12.05.2025. Click Here